Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

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Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
CAL-120 Cediranib
VEGFR/cKIT
RTK
1.037
 -0.1243 0.2989 0.0564 0.5757
6.9922
0.99099
MDA-MB-361 Cediranib
VEGFR/cKIT
RTK
2.2171
 -0.9803 0.2895 0.1040 2.2939
3.5791
0.96048
HCC1500 Cediranib
VEGFR/cKIT
RTK
3.8594
 -0.8084 0.1304 0.0735 3.4916
5.2864
0.99235
HCC1937 Cediranib
VEGFR/cKIT
RTK
7.9267
 0.2784 0.0440 0.0316 3.5480
8.352
0.99376
MDA-MB-134-VI Cediranib
VEGFR/cKIT
RTK
4.2103
 -0.9999 0.0977 0.0979 5.0000
5.2449
0.99321
CAL-51 Cediranib
VEGFR/cKIT
RTK
3.0488
 -0.1033 0.1710 0.0517 1.0331
8.8303
0.9776
SUM159PT Cediranib
VEGFR/cKIT
RTK
8.1187
 0.3173 0.0491 0.0085 2.1882
12.8042
0.99762
MDA-MB-453 Cediranib
VEGFR/cKIT
RTK
2.7824
 -0.6894 0.1569 0.0768 3.0858
3.7659
0.99464
MDA-MB-436 Cediranib
VEGFR/cKIT
RTK
3.6098
 -0.3824 0.1610 0.0446 1.8229
6.595
0.98039
CAL-85-1 Cediranib
VEGFR/cKIT
RTK
2.4003
 -0.2379 0.1869 0.0514 1.1002
6.5151
0.99569
T47D Cediranib
VEGFR/cKIT
RTK
4.1027
 -0.6403 0.1246 0.0754 2.9281
5.9706
0.99504
PDX1258 Cediranib
VEGFR/cKIT
RTK
4.7159
 -0.5611 0.0744 0.0681 4.9799
5.5703
0.99375
MCF7 Cediranib
VEGFR/cKIT
RTK
5.7041
 0.1149 0.0758 0.0191 1.5383
11.6508
0.98993
HCC1419 Cediranib
VEGFR/cKIT
RTK
5.0599
 -0.0329 0.0545 0.0124 4.9952
5.1984
0.99032
SUM1315MO2 Cediranib
VEGFR/cKIT
RTK
1.4839
 -0.2276 0.2430 0.0500 0.7936
5.924
0.99038