Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

Data Columns

  • 11 Data Columns
Name Description Display Name Data Type Unit Precision Readout Type Replicate Comments
cell
Cell reagent
Cell cell
smallMolecule
Small molecule perturbagen
Small Molecule small_molecule
primaryTarget Primary Target Text
pathway Pathway Text
gR50
Small molecule concentration in uM at which GR(c)=0.5
GR50 Text
gRmax
Normalized growth inhibition rate at the highest tested concentration
GRmax Numeric 4
gRAOC
Integral of GR(c) over the range of concentrations tested
GR_AOC Numeric 4
deathAUC
Integral of Increased Fraction Dead under the range of concentrations tested
Death_AUC Numeric 4
gRHillCoefficient
Maximal slope of the dose-response curve
GR Hill Coefficient Numeric 4
gEC50
Small molecule concentration in uM that results in 50% efficacy
GEC50 Text
gRR2
r^2 for the sigmoidal curve fit to the dose-response data
GR r2 Text
  • 11 Data Columns