Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

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Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
HCC70 Cisplatin
Chemo
Chemotherapy
1.3073
 -0.6832 0.2650 0.0820 1.3165
3.0116
0.99076
MDA-MB-157 Taxol
Chemo
Chemotherapy
0.002046
 -0.6700 0.9482 0.3487 1.9966
0.0029397
0.97064
HCC1954 Doxorubicin
Chemo
Chemotherapy
0.0071835
 -0.3378 0.7296 0.2544 1.4590
0.0086345
0.96869
MDA-MB-134-VI Taxol
Chemo
Chemotherapy
0.00012515
 -0.7183 1.3004 0.3511 0.5352
0.00075273
0.89205
HCC1954 Cisplatin
Chemo
Chemotherapy
1.2467
 -0.0741 0.2747 0.0807 1.1281
1.7233
0.97383
HCC1954 Taxol
Chemo
Chemotherapy
0.0024667
 -0.3961 0.8347 0.4142 1.6514
0.0034177
0.98666
MDA-MB-453 Taxol
Chemo
Chemotherapy
0.002374
 0.0356 0.6674 0.1683 1.2620
0.0023576
0.81734
MDA-MB-468 Doxorubicin
Chemo
Chemotherapy
0.0054214
 -0.3392 0.9121 0.3191 2.4137
0.0067542
0.99424
SK-BR-3 Taxol
Chemo
Chemotherapy
0.0019068
 -0.3401 0.8905 0.3665 2.3888
0.0023578
0.96349
PDX1258 Taxol
Chemo
Chemotherapy
0.0021522
 -0.0818 0.6797 0.2357 1.2501
0.0022935
0.98829
SK-BR-3 Doxorubicin
Chemo
Chemotherapy
0.0067336
 -0.6156 0.9421 0.3142 1.5278
0.010801
0.99572
SK-BR-3 Cisplatin
Chemo
Chemotherapy
5.1075
 0.2490 0.0978 0.0114 1.4151
5.7965
0.99044
PDX1328 Doxorubicin
Chemo
Chemotherapy
0.013267
 -0.7789 0.8023 0.1468 1.4934
0.021574
0.96338
HCC1500 Doxorubicin
Chemo
Chemotherapy
0.016258
 -0.7134 0.7518 0.1833 0.7212
0.058468
0.98572
HCC38 Cisplatin
Chemo
Chemotherapy
0.99272
 -0.1031 0.2567 0.1098 1.4350
1.1794
0.99675
Hs 578T Taxol
Chemo
Chemotherapy
0.0010154
 -0.3752 0.9535 0.4788 1.2811
0.0015458
0.95438
HCC1500 Taxol
Chemo
Chemotherapy
0.0038131
 -0.0589 0.6182 0.1433 1.8138
0.0038924
0.96247
Hs 578T Doxorubicin
Chemo
Chemotherapy
0.0041078
 -0.3466 0.8007 0.2450 1.2269
0.0052684
0.96807
HCC70 Taxol
Chemo
Chemotherapy
0.0013411
 -0.5065 0.9773 0.3742 1.1642
0.0024269
0.99734
MDA-MB-468 Cisplatin
Chemo
Chemotherapy
1.2638
 -0.2866 0.2872 0.0977 1.4057
1.9559
0.99503
HCC38 Doxorubicin
Chemo
Chemotherapy
0.0095452
 -0.4061 0.7803 0.2872 1.4810
0.01343
0.99228
MDA-MB-134-VI Cisplatin
Chemo
Chemotherapy
10.3229
 0.5019 0.0719 -0.0064 0.7594
36.1235
0.92643
Hs 578T Cisplatin
Chemo
Chemotherapy
1.5413
 0.0125 0.2347 0.0930 1.4392
1.6968
0.99339
MDA-MB-436 Doxorubicin
Chemo
Chemotherapy
0.0076138
 -0.1288 0.7061 0.0611 1.3442
0.0088093
0.99253
SUM149PT Doxorubicin
Chemo
Chemotherapy
0.0081537
 -0.3172 0.7479 0.2385 1.2885
0.010846
0.97733