Breast Cancer Profiling Project, Drug Sensitivity phase I: Fixed-cell GR measures of 35 breast cell lines to 34 small molecule perturbagens from library plate I. Dataset 2 of 2: Calculated dose response metrics - Dataset (ID:20344)

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Cell Small Molecule Primary Target Pathway GR50 GRmax GR_AOC Death_AUC GR Hill Coefficient GEC50 GR r2
MDA-MB-436 Taxol
Chemo
Chemotherapy
0.0037097
 -0.2183 0.7083 0.1530 3.2043
0.0040962
0.99739
CAMA-1 Taxol
Chemo
Chemotherapy
0.0022699
 -0.4944 0.9525 0.3547 2.4920
0.0029769
0.99478
MCF7 Taxol
Chemo
Chemotherapy
0.0013771
 -0.1059 0.7722 0.1589 1.1560
0.0016261
0.94939
BT-20 Taxol
Chemo
Chemotherapy
0.0020158
 -0.5760 0.9854 0.4456 2.0677
0.0028795
0.99355
CAL-85-1 Taxol
Chemo
Chemotherapy
0.0027273
 -0.3464 0.7931 0.3351 2.0210
0.0033785
0.95638
PDX1328 Taxol
Chemo
Chemotherapy
0.002983
 -0.5332 0.9047 0.1888 3.1886
0.0036802
0.98401
CAL-51 Taxol
Chemo
Chemotherapy
0.004167
 -0.2200 0.6694 0.1963 1.3689
0.0053072
0.99639
HCC1395 Taxol
Chemo
Chemotherapy
0.003883
 -0.4582 0.8386 0.2364 2.6973
0.0049059
0.99722
HCC1937 Taxol
Chemo
Chemotherapy
0.0024514
 0.0104 0.6576 0.2104 2.2541
0.0024561
0.99541
HCC1143 Taxol
Chemo
Chemotherapy
0.0020688
 -0.3349 0.8388 0.3074 2.5955
0.0024565
0.99279
HCC1806 Taxol
Chemo
Chemotherapy
0.0014225
 -0.2113 0.8398 0.3493 2.1569
0.0016621
0.96243
CAL-120 Taxol
Chemo
Chemotherapy
0.0028769
 -0.1987 0.7463 0.3104 2.6390
0.0032354
0.97877
HCC1419 Taxol
Chemo
Chemotherapy
0.0052608
 0.2143 0.4700 0.0981 2.1841
0.0040283
0.97754
HCC1954 Taxol
Chemo
Chemotherapy
0.0024667
 -0.3961 0.8347 0.4142 1.6514
0.0034177
0.98666
SK-BR-3 Taxol
Chemo
Chemotherapy
0.0019068
 -0.3401 0.8905 0.3665 2.3888
0.0023578
0.96349
MDA-MB-134-VI Taxol
Chemo
Chemotherapy
0.00012515
 -0.7183 1.3004 0.3511 0.5352
0.00075273
0.89205
Hs 578T Taxol
Chemo
Chemotherapy
0.0010154
 -0.3752 0.9535 0.4788 1.2811
0.0015458
0.95438
MCF 10A Taxol
Chemo
Chemotherapy
0.0026843
 -0.1256 0.7023 0.2576 1.8234
0.003018
0.9967
HCC70 Taxol
Chemo
Chemotherapy
0.0013411
 -0.5065 0.9773 0.3742 1.1642
0.0024269
0.99734
MDA-MB-157 Taxol
Chemo
Chemotherapy
0.002046
 -0.6700 0.9482 0.3487 1.9966
0.0029397
0.97064
MDA-MB-231 Taxol
Chemo
Chemotherapy
0.0023185
 -0.1204 0.7021 0.2576 1.1720
0.0026636
0.96432
SUM1315MO2 Taxol
Chemo
Chemotherapy
0.0024623
 -0.3258 0.7931 0.2940 2.0093
0.0030737
0.99498
HME1 Taxol
Chemo
Chemotherapy
0.0031675
 -0.2241 0.6794 0.2401 1.5314
0.0037399
0.98563
HCC1428 Taxol
Chemo
Chemotherapy
0.0086248
 0.0645 0.5066 0.2045 0.7260
0.0074214
0.91451
MDA-MB-453 Taxol
Chemo
Chemotherapy
0.002374
 0.0356 0.6674 0.1683 1.2620
0.0023576
0.81734