LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 38.13 | 11.8 | 1.2309 | 14.7989 | -0.0305 | -1.0000 | 0.4484 | 0.3159 |
| MCF 10A-H2B-mCherry | Dasatinib | 40.10 | 11.8 | 1.6021 | 11.394 | -0.0635 | -1.0000 | 0.6554 | 0.2648 |
| MCF 10A-H2B-mCherry | Dasatinib | 42.07 | 11.8 | 1.5059 | 10.9559 | -0.0895 | -1.0000 | 0.6771 | 0.2737 |
| MCF 10A-H2B-mCherry | Dasatinib | 44.04 | 11.8 | 1.6363 | 11.3607 | -0.0896 | -1.0000 | 0.7451 | 0.2671 |
| MCF 10A-H2B-mCherry | Dasatinib | 46.00 | 11.8 | 1.925 | 11.0714 | -0.0764 | -1.0000 | 0.7940 | 0.2467 |
| MCF 10A-H2B-mCherry | Dasatinib | 47.98 | 11.8 | 2.0992 | 7.4506 | -0.1158 | -0.5961 | 1.9728 | 0.1935 |
| MCF 10A-H2B-mCherry | Dasatinib | 49.95 | 11.8 | 2.5744 | 6.7152 | -0.1544 | -0.6110 | 2.8420 | 0.1745 |
| MCF 10A-H2B-mCherry | Dasatinib | 51.92 | 11.8 | 3.0537 | 6.5874 | -0.1653 | -0.6311 | 2.9225 | 0.1678 |
| MCF 10A-H2B-mCherry | Dasatinib | 53.89 | 11.8 | 3.6067 | 4.3874 | -0.1243 | -0.2741 | 3.3297 | 0.1500 |
| MCF 10A-H2B-mCherry | Dasatinib | 56.36 | 12.8 | 4.4755 | 5.1499 | -0.1439 | -0.2471 | 4.9992 | 0.1271 |
| MCF 10A-H2B-mCherry | Dasatinib | 58.33 | 12.8 | 4.7813 | 6.0034 | -0.2173 | -0.5391 | 5.0000 | 0.1370 |
| MCF 10A-H2B-mCherry | Dasatinib | 60.30 | 12.8 | 5.1736 | 6.2528 | -0.1534 | -0.4901 | 5.0000 | 0.1348 |
| MCF 10A-H2B-mCherry | Dasatinib | 62.27 | 12.8 | 4.3975 | 5.6665 | -0.1761 | -0.4952 | 5.0000 | 0.1176 |
| MCF 10A-H2B-mCherry | Dasatinib | 64.24 | 12.8 | 7.076 | 8.823 | -0.3039 | -1.0000 | 5.0000 | 0.1184 |
| MCF 10A-H2B-mCherry | Dasatinib | 66.21 | 12.8 | Inf | Inf | -0.3392 | -0.7266 | 2.5000 | 0.1746 |
| MCF 10A-H2B-mCherry | Dasatinib | 68.68 | 11.8 | Inf | Inf | -0.4111 | -0.4111 | 0.0000 | 0.2388 |
| MCF 10A-H2B-mCherry | Dasatinib | 70.65 | 11.8 | Inf | Inf | -0.4702 | -0.7605 | 2.5000 | 0.2422 |
| MCF 10A-H2B-mCherry | Dasatinib | 72.62 | 11.8 | Inf | Inf | -0.6968 | -0.8679 | 2.5000 | 0.2828 |
| MCF 10A-H2B-mCherry | Dasatinib | 74.59 | 11.8 | Inf | Inf | -0.7935 | -0.7935 | 0.0000 | 0.3297 |
| MCF 10A-H2B-mCherry | Dasatinib | 76.56 | 11.8 | Inf | Inf | -0.7949 | -0.9180 | 2.5000 | 0.3265 |
| MCF 10A-H2B-mCherry | Dasatinib | 78.53 | 11.8 | Inf | Inf | -0.8878 | -0.9429 | 2.5000 | 0.3438 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.50 | 11.8 | Inf | Inf | -0.9137 | -0.9137 | 0.0000 | 0.3813 |
| MCF 10A-H2B-mCherry | Dasatinib | 82.47 | 11.8 | Inf | Inf | -0.9461 | -0.9461 | 0.0000 | 0.4375 |
| MCF 10A-H2B-mCherry | Dasatinib | 84.44 | 11.8 | Inf | Inf | -0.9625 | -0.9625 | 0.0000 | 0.4367 |
| MCF 10A-H2B-mCherry | Dasatinib | 86.41 | 11.8 | Inf | Inf | -0.9407 | -0.9407 | 0.0000 | 0.4348 |