LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 64.24 | 12.8 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | -0.0006 |
| MCF 10A-H2B-mCherry | Alpelisib | 66.21 | 12.8 | Inf | Inf | 0.7208 | 0.7208 | 0.0000 | 0.0599 |
| MCF 10A-H2B-mCherry | Alpelisib | 68.68 | 11.8 | Inf | Inf | 0.5890 | 0.7519 | 2.5000 | 0.1166 |
| MCF 10A-H2B-mCherry | Alpelisib | 70.65 | 11.8 | Inf | Inf | 0.4267 | 0.6197 | 0.6734 | 0.2143 |
| MCF 10A-H2B-mCherry | Alpelisib | 72.62 | 11.8 | Inf | Inf | 0.1179 | 0.2602 | 0.5184 | 0.2709 |
| MCF 10A-H2B-mCherry | Alpelisib | 74.59 | 11.8 | Inf | Inf | -0.2722 | -0.3540 | 0.4280 | 0.3853 |
| MCF 10A-H2B-mCherry | Alpelisib | 76.56 | 11.8 | Inf | Inf | -0.3605 | -0.5430 | 0.4156 | 0.4223 |
| MCF 10A-H2B-mCherry | Alpelisib | 78.53 | 11.8 | Inf | Inf | -0.5687 | -0.7801 | 0.5348 | 0.5215 |
| MCF 10A-H2B-mCherry | Alpelisib | 80.50 | 11.8 | Inf | Inf | -0.7248 | -0.9024 | 0.5606 | 0.5652 |
| MCF 10A-H2B-mCherry | Alpelisib | 82.47 | 11.8 | Inf | Inf | -0.7155 | -0.9323 | 0.4722 | 0.5723 |
| MCF 10A-H2B-mCherry | Alpelisib | 84.44 | 11.8 | Inf | Inf | -0.6603 | -0.9436 | 0.4167 | 0.5697 |
| MCF 10A-H2B-mCherry | Alpelisib | 86.41 | 11.8 | Inf | Inf | -0.5643 | -0.9298 | 0.3611 | 0.5327 |
| MCF 10A-H2B-mCherry | Alpelisib | 88.39 | 11.8 | Inf | Inf | -0.5245 | -0.9218 | 0.3023 | 0.5225 |
| MCF 10A-H2B-mCherry | Dasatinib | 14.50 | 11.8 | 0.4949 | 9.8532 | 0.0959 | -0.7075 | 0.3145 | 0.4043 |
| MCF 10A-H2B-mCherry | Dasatinib | 16.47 | 11.8 | 0.2976 | 18.1565 | 0.0567 | -0.9754 | 0.3022 | 0.4478 |
| MCF 10A-H2B-mCherry | Dasatinib | 18.43 | 11.8 | 0.3036 | 12.6517 | 0.0458 | -0.6348 | 0.3781 | 0.4299 |
| MCF 10A-H2B-mCherry | Dasatinib | 20.40 | 11.8 | 0.3216 | 14.6959 | 0.0500 | -0.8825 | 0.3178 | 0.4415 |
| MCF 10A-H2B-mCherry | Dasatinib | 22.37 | 11.8 | 0.4115 | 15.4623 | 0.0244 | -1.0000 | 0.3218 | 0.4271 |
| MCF 10A-H2B-mCherry | Dasatinib | 24.34 | 11.8 | 0.5409 | 14.19 | -0.0125 | -1.0000 | 0.3449 | 0.4043 |
| MCF 10A-H2B-mCherry | Dasatinib | 26.31 | 11.8 | 0.6274 | 15.1152 | -0.0263 | -1.0000 | 0.3476 | 0.3868 |
| MCF 10A-H2B-mCherry | Dasatinib | 28.28 | 11.8 | 0.7954 | 18.5915 | -0.0078 | -1.0000 | 0.3491 | 0.3618 |
| MCF 10A-H2B-mCherry | Dasatinib | 30.24 | 11.8 | 1.0071 | 14.9742 | -0.0381 | -1.0000 | 0.4085 | 0.3298 |
| MCF 10A-H2B-mCherry | Dasatinib | 32.22 | 11.8 | 1.1811 | 12.756 | -0.0495 | -1.0000 | 0.4626 | 0.3081 |
| MCF 10A-H2B-mCherry | Dasatinib | 34.19 | 11.8 | 1.228 | 11.8316 | -0.0560 | -1.0000 | 0.4857 | 0.3070 |
| MCF 10A-H2B-mCherry | Dasatinib | 36.16 | 11.8 | 1.1086 | 14.38 | -0.0457 | -1.0000 | 0.4301 | 0.3274 |