LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 88.39 | 11.8 | Inf | Inf | -0.9411 | -0.9411 | 0.0000 | 0.4784 |
| MCF 10A-H2B-mCherry | Etoposide | 14.50 | 11.8 | 1.8736 | 7.8032 | 0.0786 | -0.4739 | 1.6271 | 0.2461 |
| MCF 10A-H2B-mCherry | Etoposide | 16.47 | 11.8 | 1.6068 | 6.9325 | 0.0415 | -0.5219 | 0.9526 | 0.2668 |
| MCF 10A-H2B-mCherry | Etoposide | 18.43 | 11.8 | 1.5522 | 7.8666 | 0.0158 | -0.6134 | 0.7772 | 0.2740 |
| MCF 10A-H2B-mCherry | Etoposide | 20.40 | 11.8 | 1.2916 | 6.3768 | -0.0004 | -0.5932 | 0.7629 | 0.2949 |
| MCF 10A-H2B-mCherry | Etoposide | 22.37 | 11.8 | 1.1454 | 4.6858 | -0.0123 | -0.5864 | 0.7803 | 0.3018 |
| MCF 10A-H2B-mCherry | Etoposide | 24.34 | 11.8 | 0.8442 | 5.271 | 0.0105 | -0.5578 | 0.8577 | 0.3466 |
| MCF 10A-H2B-mCherry | Etoposide | 26.31 | 11.8 | 0.487 | 1.8458 | -0.0111 | -0.3810 | 0.6094 | 0.3856 |
| MCF 10A-H2B-mCherry | Etoposide | 28.28 | 11.8 | 0.2715 | 0.4074 | -0.0130 | -0.1401 | 0.6673 | 0.4323 |
| MCF 10A-H2B-mCherry | Etoposide | 30.24 | 11.8 | 0.2458 | 0.2543 | 0.0105 | -0.0114 | 0.9421 | 0.4260 |
| MCF 10A-H2B-mCherry | Etoposide | 32.22 | 11.8 | 0.2117 | 0.214 | -0.0119 | 0.0160 | 1.2520 | 0.4334 |
| MCF 10A-H2B-mCherry | Etoposide | 34.19 | 11.8 | 0.2149 | 0.2129 | -0.0119 | 0.0212 | 1.4114 | 0.4279 |
| MCF 10A-H2B-mCherry | Etoposide | 36.16 | 11.8 | 0.2177 | 0.2256 | -0.0071 | -0.0152 | 1.0743 | 0.4414 |
| MCF 10A-H2B-mCherry | Etoposide | 38.13 | 11.8 | 0.2111 | 0.2347 | 0.0138 | -0.0519 | 1.0632 | 0.4553 |
| MCF 10A-H2B-mCherry | Etoposide | 40.10 | 11.8 | 0.2385 | 0.2529 | -0.0332 | -0.0349 | 1.2780 | 0.4395 |
| MCF 10A-H2B-mCherry | Etoposide | 42.07 | 11.8 | 0.2085 | 0.2556 | -0.0863 | -0.1072 | 1.1283 | 0.4606 |
| MCF 10A-H2B-mCherry | Etoposide | 44.04 | 11.8 | 0.1899 | 0.2227 | -0.0658 | -0.0709 | 1.0300 | 0.4543 |
| MCF 10A-H2B-mCherry | Etoposide | 46.00 | 11.8 | 0.1489 | 0.1733 | -0.0796 | -0.0732 | 1.1118 | 0.4814 |
| MCF 10A-H2B-mCherry | Etoposide | 47.98 | 11.8 | 0.1702 | 0.2039 | -0.1583 | -0.0914 | 2.9692 | 0.4899 |
| MCF 10A-H2B-mCherry | Etoposide | 49.95 | 11.8 | 0.148 | 0.2092 | -0.1610 | -0.1704 | 2.8308 | 0.5196 |
| MCF 10A-H2B-mCherry | Etoposide | 51.92 | 11.8 | 0.1156 | 0.1784 | -0.2132 | -0.1905 | 2.7864 | 0.5566 |
| MCF 10A-H2B-mCherry | Etoposide | 53.89 | 11.8 | 0.105 | 0.27 | -0.2088 | -0.3323 | 2.6882 | 0.5777 |
| MCF 10A-H2B-mCherry | Etoposide | 56.36 | 12.8 | 0.1038 | 0.1853 | -0.1609 | -0.2487 | 2.7472 | 0.5857 |
| MCF 10A-H2B-mCherry | Etoposide | 58.33 | 12.8 | 0.08 | 1.0748 | -0.1876 | -0.5621 | 2.6279 | 0.5816 |
| MCF 10A-H2B-mCherry | Etoposide | 60.30 | 12.8 | Inf | Inf | -0.0882 | -0.1344 | 2.5000 | 0.6136 |