LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 25.25 | 13.3 | 13.7447 | 50.8693 | 0.5662 | -0.9329 | 0.8377 | 0.0699 |
| MCF 10A-H2B-mCherry | Alpelisib | 43.03 | 13.3 | 23.3924 | 88.1783 | 0.7153 | -0.9969 | 0.8352 | 0.0518 |
| MCF 10A-H2B-mCherry | Alpelisib | 27.48 | 13.3 | 20.0615 | 109.7735 | 0.5940 | -1.0000 | 0.7179 | 0.0765 |
| MCF 10A-H2B-mCherry | Alpelisib | 45.25 | 13.3 | Inf | 19.4732 | 0.7923 | -0.0908 | 3.0690 | 0.0228 |
| MCF 10A-H2B-mCherry | Dasatinib | 63.02 | 13.3 | 2.5721 | 2.791 | -0.2366 | -0.2566 | 5.0000 | 0.2329 |
| MCF 10A-H2B-mCherry | Alpelisib | 47.47 | 13.3 | Inf | 17.0493 | 0.7926 | -0.0881 | 3.2633 | 0.0135 |
| MCF 10A-H2B-mCherry | Dasatinib | 16.73 | 13.3 | 0.2398 | 0.1356 | 0.1161 | 0.2329 | 1.0987 | 0.3477 |
| MCF 10A-H2B-mCherry | Dasatinib | 18.59 | 13.3 | 0.1649 | 0.1073 | 0.0926 | 0.2004 | 1.1913 | 0.3926 |
| MCF 10A-H2B-mCherry | Dasatinib | 20.81 | 13.3 | 0.1678 | 0.1291 | 0.0159 | 0.1178 | 1.0222 | 0.4177 |
| MCF 10A-H2B-mCherry | Dasatinib | 23.04 | 13.3 | 0.2224 | 0.205 | -0.0118 | 0.0328 | 0.8163 | 0.4098 |
| MCF 10A-H2B-mCherry | Dasatinib | 25.25 | 13.3 | 0.313 | 0.4332 | -0.0328 | -0.1134 | 0.6523 | 0.3950 |
| MCF 10A-H2B-mCherry | Dasatinib | 27.48 | 13.3 | 0.3676 | 0.6715 | -0.0294 | -0.2072 | 0.5849 | 0.3882 |
| MCF 10A-H2B-mCherry | Dasatinib | 29.70 | 13.3 | 0.4516 | 1.1873 | -0.0290 | -0.3307 | 0.5282 | 0.3756 |
| MCF 10A-H2B-mCherry | Dasatinib | 31.92 | 13.3 | 0.473 | 2.4894 | -0.0595 | -0.5851 | 0.4682 | 0.3814 |
| MCF 10A-H2B-mCherry | Dasatinib | 34.14 | 13.3 | 0.5075 | 2.7807 | -0.0344 | -0.6161 | 0.4727 | 0.3748 |
| MCF 10A-H2B-mCherry | Dasatinib | 36.36 | 13.3 | 0.5258 | 2.9059 | -0.0324 | -0.6249 | 0.4713 | 0.3740 |
| MCF 10A-H2B-mCherry | Dasatinib | 38.59 | 13.3 | 0.5386 | 3.3837 | -0.0418 | -0.7129 | 0.4750 | 0.3711 |
| MCF 10A-H2B-mCherry | Dasatinib | 40.81 | 13.3 | 0.6387 | 3.8735 | -0.0618 | -0.7504 | 0.4977 | 0.3511 |
| MCF 10A-H2B-mCherry | Dasatinib | 43.03 | 13.3 | 0.7522 | 3.8263 | -0.0651 | -0.7385 | 0.5434 | 0.3324 |
| MCF 10A-H2B-mCherry | Dasatinib | 45.25 | 13.3 | 1.0589 | 4.5149 | -0.0802 | -0.7836 | 0.6356 | 0.2946 |
| MCF 10A-H2B-mCherry | Dasatinib | 47.47 | 13.3 | 1.2344 | 5.6634 | -0.1100 | -0.9056 | 0.6840 | 0.2827 |
| MCF 10A-H2B-mCherry | Dasatinib | 49.69 | 13.3 | 1.5612 | 5.8184 | -0.1606 | -0.9355 | 0.8455 | 0.2645 |
| MCF 10A-H2B-mCherry | Dasatinib | 51.92 | 13.3 | 1.7473 | 4.2745 | -0.1576 | -0.6600 | 1.3427 | 0.2569 |
| MCF 10A-H2B-mCherry | Dasatinib | 54.14 | 13.3 | 1.8804 | 4.0904 | -0.1842 | -0.6345 | 1.9899 | 0.2646 |
| MCF 10A-H2B-mCherry | Etoposide | 18.59 | 13.3 | 0.4472 | 0.5118 | -0.0195 | -0.0809 | 1.1143 | 0.3622 |