LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 16.73 | 13.3 | 0.0047 | 0.0097 | -0.6834 | -0.7046 | 1.2187 | 0.6742 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.82 | 13.4 | 2.6268 | 3.1186 | -0.6670 | -0.6812 | 5.0000 | 0.2539 |
| MCF 10A-H2B-mCherry | Taxol | 23.04 | 13.3 | 0.002 | 0.0039 | -0.7844 | -0.6681 | 1.2967 | 0.8096 |
| MCF 10A-H2B-mCherry | Dasatinib | 51.92 | 13.3 | 1.7473 | 4.2745 | -0.1576 | -0.6600 | 1.3427 | 0.2569 |
| MCF 10A-H2B-mCherry | Taxol | 25.25 | 13.3 | 0.0019 | 0.0035 | -0.7891 | -0.6591 | 1.4064 | 0.8233 |
| MCF 10A-H2B-mCherry | Dasatinib | 76.38 | 13.4 | 2.6411 | 3.1142 | -0.6260 | -0.6410 | 5.0000 | 0.2153 |
| MCF 10A-H2B-mCherry | Taxol | 27.48 | 13.3 | 0.0019 | 0.0032 | -0.7766 | -0.6351 | 1.5305 | 0.8280 |
| MCF 10A-H2B-mCherry | Dasatinib | 54.14 | 13.3 | 1.8804 | 4.0904 | -0.1842 | -0.6345 | 1.9899 | 0.2646 |
| MCF 10A-H2B-mCherry | Alpelisib | 34.14 | 13.3 | 33.6323 | 138.7884 | 0.6705 | -0.6260 | 0.5249 | 0.0816 |
| MCF 10A-H2B-mCherry | Dasatinib | 78.60 | 13.4 | 2.6077 | 3.0672 | -0.6115 | -0.6256 | 5.0000 | 0.2331 |
| MCF 10A-H2B-mCherry | Dasatinib | 36.36 | 13.3 | 0.5258 | 2.9059 | -0.0324 | -0.6249 | 0.4713 | 0.3740 |
| MCF 10A-H2B-mCherry | Dasatinib | 34.14 | 13.3 | 0.5075 | 2.7807 | -0.0344 | -0.6161 | 0.4727 | 0.3748 |
| MCF 10A-H2B-mCherry | Taxol | 29.70 | 13.3 | 0.0018 | 0.0028 | -0.7417 | -0.6033 | 1.6514 | 0.8307 |
| MCF 10A-H2B-mCherry | Dasatinib | 31.92 | 13.3 | 0.473 | 2.4894 | -0.0595 | -0.5851 | 0.4682 | 0.3814 |
| MCF 10A-H2B-mCherry | Palbociclib | 78.60 | 13.4 | 3.8114 | 5.377 | -0.0290 | -0.5698 | 2.1381 | 0.1010 |
| MCF 10A-H2B-mCherry | Taxol | 31.92 | 13.3 | 0.0016 | 0.0025 | -0.6609 | -0.5655 | 1.5990 | 0.8378 |
| MCF 10A-H2B-mCherry | Dasatinib | 74.16 | 13.4 | 2.6047 | 3.0088 | -0.5134 | -0.5296 | 5.0000 | 0.2140 |
| MCF 10A-H2B-mCherry | Taxol | 34.14 | 13.3 | 0.0015 | 0.0022 | -0.6309 | -0.4906 | 1.7169 | 0.8190 |
| MCF 10A-H2B-mCherry | Neratinib | 76.38 | 13.4 | 1.1623 | 1.4074 | -0.3862 | -0.4851 | 3.9610 | 0.2050 |
| MCF 10A-H2B-mCherry | Dasatinib | 71.94 | 13.4 | 2.6626 | 3.0476 | -0.4700 | -0.4838 | 5.0000 | 0.1943 |
| MCF 10A-H2B-mCherry | Vorinostat | 16.73 | 13.3 | 0.6881 | 1.3581 | -0.2534 | -0.4659 | 0.9685 | 0.4010 |
| MCF 10A-H2B-mCherry | Palbociclib | 69.71 | 13.4 | 3.1977 | 5.394 | -0.0186 | -0.4657 | 1.2682 | 0.1393 |
| MCF 10A-H2B-mCherry | Taxol | 36.36 | 13.3 | 0.0014 | 0.002 | -0.5106 | -0.4415 | 1.8237 | 0.8179 |
| MCF 10A-H2B-mCherry | Palbociclib | 67.47 | 13.3 | 2.3141 | 4.1619 | 0.0014 | -0.4295 | 1.0422 | 0.1732 |
| MCF 10A-H2B-mCherry | Taxol | 80.82 | 13.4 | 0.0029 | 0.0033 | -0.4208 | -0.4210 | 5.0000 | 0.7492 |