LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)

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Cell Small Molecule Time Point (hr) Time Interval (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Trametinib 20.81 13.3
0.0023
0.0021
 0.0576 0.0696 1.6693 0.6766
MCF 10A-H2B-mCherry Taxol 74.16 13.4
0.0024
0.0026
 -0.2040 -0.1914 4.6471 0.6619
MCF 10A-H2B-mCherry Taxol 20.81 13.3
0.0024
0.0055
 -0.7843 -0.7290 1.0789 0.7803
MCF 10A-H2B-mCherry Taxol 71.94 13.4
0.0024
0.0025
 -0.4059 -0.1917 5.0000 0.6660
MCF 10A-H2B-mCherry Trametinib 29.70 13.3
0.0026
0.0026
 -0.0081 0.0005 1.4257 0.7007
MCF 10A-H2B-mCherry Taxol 76.38 13.4
0.0027
0.003
 -0.3872 -0.2827 5.0000 0.7081
MCF 10A-H2B-mCherry Taxol 78.60 13.4
0.0027
0.003
 -0.4567 -0.3897 5.0000 0.7535
MCF 10A-H2B-mCherry Taxol 80.82 13.4
0.0029
0.0033
 -0.4208 -0.4210 5.0000 0.7492
MCF 10A-H2B-mCherry Trametinib 31.92 13.3
0.0029
0.003
 0.0010 -0.0067 1.2681 0.6896
MCF 10A-H2B-mCherry Trametinib 18.59 13.3
0.0031
0.0024
 0.1609 0.1780 1.5913 0.5859
MCF 10A-H2B-mCherry Taxol 18.59 13.3
0.0034
0.0077
 -0.7352 -0.7179 1.1107 0.7117
MCF 10A-H2B-mCherry Trametinib 34.14 13.3
0.0035
0.0036
 -0.0098 -0.0135 1.1220 0.6699
MCF 10A-H2B-mCherry Trametinib 36.36 13.3
0.0039
0.0039
 0.0199 0.0015 1.1076 0.6499
MCF 10A-H2B-mCherry Taxol 16.73 13.3
0.0047
0.0097
 -0.6834 -0.7046 1.2187 0.6742
MCF 10A-H2B-mCherry Trametinib 38.59 13.3
0.005
0.0052
 0.0005 -0.0200 0.9820 0.6323
MCF 10A-H2B-mCherry Trametinib 16.73 13.3
0.0054
0.0032
 0.1822 0.2568 1.3893 0.5061
MCF 10A-H2B-mCherry Taxol 15.91 13.5
0.0055
0.0121
 -0.6952 -0.7201 1.1326 0.6312
MCF 10A-H2B-mCherry Trametinib 15.91 13.5
0.0058
0.003
 0.3307 0.3502 1.7943 0.4481
MCF 10A-H2B-mCherry Trametinib 40.81 13.3
0.0061
0.0062
 0.0257 -0.0045 1.0021 0.6032
MCF 10A-H2B-mCherry Trametinib 43.03 13.3
0.0081
0.0081
 0.0108 -0.0039 1.0504 0.5720
MCF 10A-H2B-mCherry Trametinib 45.25 13.3
0.0119
0.0117
 0.0297 0.0122 1.2484 0.5302
MCF 10A-H2B-mCherry Trametinib 47.47 13.3
0.014
0.0132
 0.0446 0.0490 1.9591 0.5006
MCF 10A-H2B-mCherry Trametinib 51.92 13.3
0.0175
0.0167
 0.0376 0.0432 1.9155 0.4714
MCF 10A-H2B-mCherry Trametinib 56.36 13.3
0.0178
0.0174
 0.0306 0.0301 2.2588 0.4660
MCF 10A-H2B-mCherry Trametinib 49.69 13.3
0.0178
0.017
 0.0450 0.0418 2.0225 0.4779