LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 13 of 15: Time-dependent dose-response metrics for biological replicate 1. - Dataset (ID:20321)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 31.92 | 13.3 | 0.473 | 2.4894 | -0.0595 | -0.5851 | 0.4682 | 0.3814 |
| MCF 10A-H2B-mCherry | Dasatinib | 34.14 | 13.3 | 0.5075 | 2.7807 | -0.0344 | -0.6161 | 0.4727 | 0.3748 |
| MCF 10A-H2B-mCherry | Dasatinib | 36.36 | 13.3 | 0.5258 | 2.9059 | -0.0324 | -0.6249 | 0.4713 | 0.3740 |
| MCF 10A-H2B-mCherry | Dasatinib | 38.59 | 13.3 | 0.5386 | 3.3837 | -0.0418 | -0.7129 | 0.4750 | 0.3711 |
| MCF 10A-H2B-mCherry | Dasatinib | 40.81 | 13.3 | 0.6387 | 3.8735 | -0.0618 | -0.7504 | 0.4977 | 0.3511 |
| MCF 10A-H2B-mCherry | Dasatinib | 43.03 | 13.3 | 0.7522 | 3.8263 | -0.0651 | -0.7385 | 0.5434 | 0.3324 |
| MCF 10A-H2B-mCherry | Dasatinib | 45.25 | 13.3 | 1.0589 | 4.5149 | -0.0802 | -0.7836 | 0.6356 | 0.2946 |
| MCF 10A-H2B-mCherry | Dasatinib | 47.47 | 13.3 | 1.2344 | 5.6634 | -0.1100 | -0.9056 | 0.6840 | 0.2827 |
| MCF 10A-H2B-mCherry | Dasatinib | 49.69 | 13.3 | 1.5612 | 5.8184 | -0.1606 | -0.9355 | 0.8455 | 0.2645 |
| MCF 10A-H2B-mCherry | Dasatinib | 51.92 | 13.3 | 1.7473 | 4.2745 | -0.1576 | -0.6600 | 1.3427 | 0.2569 |
| MCF 10A-H2B-mCherry | Dasatinib | 54.14 | 13.3 | 1.8804 | 4.0904 | -0.1842 | -0.6345 | 1.9899 | 0.2646 |
| MCF 10A-H2B-mCherry | Dasatinib | 56.36 | 13.3 | 2.0599 | 2.5902 | -0.1942 | -0.2943 | 2.4725 | 0.2544 |
| MCF 10A-H2B-mCherry | Dasatinib | 58.58 | 13.3 | 2.2428 | 2.6437 | -0.2202 | -0.2823 | 3.2537 | 0.2503 |
| MCF 10A-H2B-mCherry | Dasatinib | 60.80 | 13.3 | 2.6142 | 2.8457 | -0.2483 | -0.2665 | 5.0000 | 0.2204 |
| MCF 10A-H2B-mCherry | Dasatinib | 63.02 | 13.3 | 2.5721 | 2.791 | -0.2366 | -0.2566 | 5.0000 | 0.2329 |
| MCF 10A-H2B-mCherry | Dasatinib | 65.24 | 13.3 | 2.6262 | 2.9014 | -0.3088 | -0.3272 | 5.0000 | 0.2266 |
| MCF 10A-H2B-mCherry | Dasatinib | 67.47 | 13.3 | 2.6267 | 2.9115 | -0.3174 | -0.3370 | 5.0000 | 0.2139 |
| MCF 10A-H2B-mCherry | Etoposide | 16.73 | 13.3 | 0.56 | 0.6179 | -0.0203 | -0.0675 | 1.2871 | 0.3359 |
| MCF 10A-H2B-mCherry | Etoposide | 18.59 | 13.3 | 0.4472 | 0.5118 | -0.0195 | -0.0809 | 1.1143 | 0.3622 |
| MCF 10A-H2B-mCherry | Etoposide | 20.81 | 13.3 | 0.4019 | 0.4581 | -0.0197 | -0.0737 | 1.0552 | 0.3661 |
| MCF 10A-H2B-mCherry | Etoposide | 23.04 | 13.3 | 0.3745 | 0.3923 | 0.0069 | -0.0274 | 1.1560 | 0.3700 |
| MCF 10A-H2B-mCherry | Etoposide | 25.25 | 13.3 | 0.3754 | 0.3873 | -0.0229 | -0.0209 | 1.3191 | 0.3639 |
| MCF 10A-H2B-mCherry | Etoposide | 27.48 | 13.3 | 0.3413 | 0.3499 | -0.0200 | -0.0171 | 1.3558 | 0.3726 |