Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
Small Molecules Studied
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| HMS LINCS ID | Name | Alternative Names | LINCS ID | Structure Image | PubChem CID |
|---|---|---|---|---|---|
| 10246-1 | CPT-11 | Irinotecan | LSM-2167 |  | 60838 |
| 10252-1 | Gemcitabine | Gemzar | LSM-5333 |  | 60750 |
| 10278-1 | Topotecan | Hycamtin | LSM-5662 |  | 60700 |
| 10133-2 | Afatinib | BIBW-2992 | LSM-43226 |  | 57519523 |
| 10263-1 | LBH589 | Panobinostat | LSM-4284 |  | 57519507 |
| 10345-3 | Torkinib | PP242 | LSM-6357 |  | 57347681 |
| 10240-1 | AS-252424 | LSM-4263 |  | 56965900 | |
| 10219-2 | U-0126 | LSM-42806 |  | 5637 | |
| 10021-5 | Tozasertib | VX680; MK-0457 | LSM-1021 |  | 5494449 |
| 10275-1 | (Z)-4-Hydroxytamoxifen | LSM-43294 |  | 53770298 | |
| 10518-1 | Sulindac sulfide |  | 5352624 | ||
| 10235-2 | Everolimus | RAD001 | LSM-4258 |  | 53398658 |
| 10189-2 | Bosutinib | SKI-606 | LSM-1190 |  | 5328940 |
| 10281-1 | Vinorelbine | Navelbine | LSM-6302 |  | 5311497 |
| 10282-1 | Vorinostat | suberoylanilide hydroxamic acid (SAHA); Zolinza | LSM-3828 |  | 5311 |
| 10269-1 | Oxaliplatin | Eloxatin | LSM-44941 |  | 5310940 |
| 10023-3 | Imatinib | Gleevec; Glivec; CGP-57148B; STI-571 | LSM-1023 |  | 5291 |
| 10343-1 | Baicalein | LSM-6355 |  | 5281605 | |
| 10242-1 | Carboplatin | LSM-44959 |  | 5237030 | |
| 10515-1 | QNZ | EVP4593 |  | 509554 | |
| 10052-3 | Sirolimus | Rapamycin | LSM-1052 |  | 5040 |
| 10029-2 | GW-5074 | LSM-1029 |  | 5034 | |
| 10243-1 | CGC-11047 | PG11047 | LSM-4266 |  | 476863 |
| 10271-2 | PD 98059 | LSM-3394 |  | 4713 | |
| 10062-3 | GSK1070916 | KIN001-216 | LSM-1062 |  | 46885626 |