Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9035.018 | 0.1244 | -0.2396 | 2.1555 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7803.042 | 0.1324 | -0.0219 | 2.8270 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7801.018 | 0.5414 | -0.2915 | 0.5913 | |
| BT-474 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7798.018 | 0.2955 | -0.1392 | 1.4461 | |
| HCC1937 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7832.042 | 0.6277 | 0.3904 | 1.2810 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7807.042 | 0.1305 | -0.2683 | 2.0250 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7805.018 | 0.3275 | -0.2455 | 1.1451 | |
| MDA-MB-175-VII | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7886.042 | 0.5361 | -0.2378 | 0.6462 | |
| HCC1143 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7809.018 | 0.4778 | 0.2866 | 1.6742 | |
| MDA-MB-361 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7895.018 | 0.1968 | -0.4318 | 1.2916 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7808.052 | 0.0504 | -0.3990 | 2.4842 | |
| MDA-MB-415 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7897.018 | 0.5921 | 0.0755 | 0.8448 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7814.042 | 0.1310 | -0.8215 | 0.8414 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7813.018 | 0.0020 | -0.9987 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7816.042 | 0.1588 | -0.7217 | 0.9332 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7794.018 | 0.1761 | -0.2882 | 1.6812 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7820.042 | 0.5850 | -0.2846 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7821.042 | 0.5358 | -0.3539 | 0.5522 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7825.018 | 0.2233 | -0.0642 | 1.9741 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7829.042 | 0.1166 | -0.3673 | 1.8673 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7791.018 | 0.7449 | 0.4177 | 0.8558 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7793.018 | 0.1156 | -0.6105 | 1.3186 | |
| 184A1 | NM | Basal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7787.018 | 0.8848 | 0.4481 | 0.3791 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7812.042 | 0.2610 | -0.4977 | 0.9722 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7818.018 | 0.5805 | 0.1564 | 0.9928 |