Growth rate-corrected (GR) dose-response metrics across a panel of 71 breast cancer cell lines treated with a library of small molecule and antibody perturbagens. Dataset 1 of 4: Relative cell counts and normalized growth rate inhibition values across technical replicates. - Dataset (ID:20268)
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| Cell | Clinical Subtype | Transcriptional Subtype | Small Molecule | Antibody | Perturbagen Target | Perturbagen Class | Perturbagen Concentration | Perturbagen Conc Unit | Biological Replicate ID | Relative Cell Count | Normalized Growth Rate Inhibition Value | Nominal Division Rate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HCC3153 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7853.042 | 0.3806 | 0.1561 | 1.7624 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7856.018 | 0.3264 | -0.3933 | 0.9388 | |
| HCC70 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7857.042 | 0.3040 | -0.2641 | 1.1910 | |
| HMT-3522 S1 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7911.018 | 0.2602 | -0.0324 | 1.8543 | |
| Hs 578T | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7861.018 | 0.0693 | -0.9140 | 0.8485 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7807.042 | 0.1305 | -0.2683 | 2.0250 | |
| BT-483 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7801.018 | 0.5414 | -0.2915 | 0.5913 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7804.042 | 0.0707 | -0.3084 | 2.4955 | |
| HBL-100 | Unknown | Unknown | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7808.052 | 0.0504 | -0.3990 | 2.4842 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7794.018 | 0.1761 | -0.2882 | 1.6812 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7803.042 | 0.1324 | -0.0219 | 2.8270 | |
| BT-549 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9024.018 | 0.0523 | -0.2948 | 2.8306 | |
| CAMA-1 | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7805.018 | 0.3275 | -0.2455 | 1.1451 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7793.018 | 0.1156 | -0.6105 | 1.3186 | |
| HCC1187 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7811.018 | 0.2759 | -0.8713 | 0.4694 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7813.018 | 0.0020 | -0.9987 | 0.8420 | |
| HCC1395 | TNBC | Basal B | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7814.042 | 0.1310 | -0.8215 | 0.8414 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7820.042 | 0.5850 | -0.2846 | 0.5216 | |
| HCC1419 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7821.042 | 0.5358 | -0.3539 | 0.5522 | |
| HCC1569 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7825.018 | 0.2233 | -0.0642 | 1.9741 | |
| HCC1806 | TNBC | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7829.042 | 0.1166 | -0.3673 | 1.8673 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7835.018 | 0.6306 | -0.1584 | 0.5326 | |
| HCC1954 | HER2amp | Basal A | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7836.018 | 0.2673 | -0.4092 | 1.0819 | |
| AU565 | HER2amp | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 9035.018 | 0.1244 | -0.2396 | 2.1555 | |
| 600MPE | HR+ | Luminal | Vinorelbine | TUBB | TUBB | 9.27 | uM | 7791.018 | 0.7449 | 0.4177 | 0.8558 |