Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF or four kinase inhibitors - Dataset (ID:20267)

Proteins Studied

LINCS ID Name HMS LINCS ID UniProt ID Alternative Names Provider Mutation Phosphlorylation State Domain Protein Description
201314 H2A.X (pS139) 201314 P16104 pS139
201316 Beta-actin 201316 P60709
Actin, cytoplasmic 1
201348 Vimentin 201348 P08670
201335 Rb (pS807) 201335 P06400 pS807
201336 Rb (pS811) 201336 P06400 pS811
201337 ERK-1 (pT202) 201337 P27361 pT202
201338 ERK-2 (pT185) 201338 P28482 pT185
201339 Aurora kinase A (pT288) 201339 O14965 pT288
201340 Aurora kinase B (pT232) 201340 Q96GD4 pT232
201341 Aurora kinase C (pT198) 201341 Q9UQB9 pT198
201342 S6 201342 P62753
40S ribosomal protein S6, Phosphoprotein NP33
201343 PARP-1 (D214-cleaved) 201343 P09874 D214-cleaved
201344 p27Kip1 201344 P46527
Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27
201349 NF-kB p65 201349 Q04206
Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3
201350 FOXO3a 201350 O43524
Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1
201351 Cyclin-D1 201351 P24385
G1/S-specific cyclin-D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene
201352 BAX 201352 Q07812
Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4
201353 E-cadherin 201353 P12830
CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD324
201357 EGF 201357 P01133
Epidermal Growth Factor; Urogastrone; URG
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