Highly-multiplexed imaging by Cyclic Immunofluorescence (CycIF) of protein levels and protein phosphorylation states in the MCF 10A breast cell line treated with EGF or four kinase inhibitors - Dataset (ID:20267)
- Detail
- Small Molecules Studied
- Cell Lines Studied
- Proteins Studied
- Antibodies Studied
- Other Reagents Studied
- Results
Proteins Studied
Download: Excel (XLSX), Comma-separated (CSV)
LINCS ID | Name | HMS LINCS ID | UniProt ID | Alternative Names | Provider | Mutation | Phosphlorylation State | Domain | Protein Description |
---|---|---|---|---|---|---|---|---|---|
201314 | H2A.X (pS139) | 201314 | P16104 | pS139 | |||||
201316 | Beta-actin | 201316 | P60709 | Actin, cytoplasmic 1 | |||||
201335 | Rb (pS807) | 201335 | P06400 | pS807 | |||||
201336 | Rb (pS811) | 201336 | P06400 | pS811 | |||||
201337 | ERK-1 (pT202) | 201337 | P27361 | pT202 | |||||
201338 | ERK-2 (pT185) | 201338 | P28482 | pT185 | |||||
201339 | Aurora kinase A (pT288) | 201339 | O14965 | pT288 | |||||
201340 | Aurora kinase B (pT232) | 201340 | Q96GD4 | pT232 | |||||
201341 | Aurora kinase C (pT198) | 201341 | Q9UQB9 | pT198 | |||||
201342 | S6 | 201342 | P62753 | 40S ribosomal protein S6, Phosphoprotein NP33 | |||||
201343 | PARP-1 (D214-cleaved) | 201343 | P09874 | D214-cleaved | |||||
201344 | p27Kip1 | 201344 | P46527 | Cyclin-dependent kinase inhibitor 1B; Cyclin-dependent kinase inhibitor p27 | |||||
201348 | Vimentin | 201348 | P08670 | ||||||
201349 | NF-kB p65 | 201349 | Q04206 | Transcription factor p65; Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 | |||||
201350 | FOXO3a | 201350 | O43524 | Forkhead box protein O3; AF6q21 protein; Forkhead in rhabdomyosarcoma-like 1 | |||||
201351 | Cyclin-D1 | 201351 | P24385 | G1/S-specific cyclin-D1; B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogene | |||||
201352 | BAX | 201352 | Q07812 | Apoptosis regulator BAX; Bcl-2-like protein 4; Bcl2-L-4 | |||||
201353 | E-cadherin | 201353 | P12830 | CAM 120/80; Epithelial cadherin; E-cadherin; Uvomorulin; CD324 | |||||
201357 | EGF | 201357 | P01133 | Epidermal Growth Factor; Urogastrone; URG | PeproTech |