Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Omipalisib | 1 | uM | 2 | 156.25 | 57.48 | 5.33 | 446.92 | 0.0124 | -0.5782 |
| MCF 10A | Omipalisib | 3.1623 | uM | 2 | 156.25 | 57.48 | 6.33 | 446.92 | 0.0147 | -0.5311 |
| MCF 10A | Omipalisib | 3.1623 | uM | 2 | 312.50 | 134.46 | 6.33 | 1303.25 | 0.0048 | -0.6121 |
| MCF 10A | Omipalisib | 0.31623 | uM | 2 | 156.25 | 57.48 | 9.67 | 446.92 | 0.0204 | -0.4813 |
| MCF 10A | Omipalisib | 1 | uM | 2 | 312.50 | 134.46 | 12.33 | 1303.25 | 0.0106 | -0.5535 |
| MCF 10A | Omipalisib | 10 | uM | 2 | 156.25 | 57.48 | 14.00 | 446.92 | 0.0335 | -0.3884 |
| BT-20 | Omipalisib | 10 | uM | 4 | 156.25 | 44.67 | 16.00 | 75.92 | 0.2064 | -0.7336 |
| MCF 10A | Omipalisib | 0.31623 | uM | 2 | 312.50 | 134.46 | 16.33 | 1303.25 | 0.0133 | -0.5026 |
| MCF 10A | Omipalisib | 0.1 | uM | 2 | 156.25 | 57.48 | 18.33 | 446.92 | 0.0394 | -0.3560 |
| MCF 10A | Omipalisib | 3.1623 | uM | 2 | 625.00 | 277.50 | 19.00 | 3384.25 | 0.0057 | -0.5276 |
| BT-20 | Omipalisib | 3.1623 | uM | 4 | 156.25 | 44.67 | 20.33 | 75.92 | 0.2822 | -0.6815 |
| MCF7 | Taxol | 0.31623 | uM | 1 | 156.25 | 31.46 | 21.67 | 70.42 | 0.3104 | -0.2753 |
| MCF 10A | Omipalisib | 1 | uM | 2 | 625.00 | 277.50 | 21.67 | 3384.25 | 0.0064 | -0.5083 |
| MCF7 | NVP-TAE684 | 1 | uM | 1 | 156.25 | 31.46 | 22.00 | 85.83 | 0.2617 | -0.2334 |
| BT-20 | Omipalisib | 3.1623 | uM | 3 | 156.25 | 49.48 | 22.33 | 96.33 | 0.2307 | -0.5712 |
| MCF 10A | 17-AAG | 1 | uM | 7 | 156.25 | 15.92 | 23.67 | 169.42 | 0.1346 | 0.0922 |
| MCF 10A | Lapatinib | 10 | uM | 7 | 156.25 | 15.92 | 25.33 | 169.42 | 0.1461 | 0.1273 |
| MCF7 | Palbociclib | 3.1623 | uM | 1 | 156.25 | 31.46 | 26.00 | 70.42 | 0.3832 | -0.1385 |
| MCF7 | NVP-TAE684 | 10 | uM | 1 | 156.25 | 31.46 | 26.00 | 85.83 | 0.3193 | -0.1298 |
| MCF 10A | Linsitinib | 19.9526 | uM | 7 | 156.25 | 15.92 | 26.33 | 169.42 | 0.1594 | 0.1463 |
| MCF 10A | 17-AAG | 3.1623 | uM | 7 | 156.25 | 15.92 | 26.67 | 169.42 | 0.1600 | 0.1624 |
| MCF7 | Taxol | 0.1 | uM | 1 | 156.25 | 31.46 | 27.00 | 70.42 | 0.3834 | -0.1332 |
| MCF 10A | Omipalisib | 0.1 | uM | 2 | 312.50 | 134.46 | 27.33 | 1303.25 | 0.0209 | -0.4120 |
| MCF 10A | NVP-TAE684 | 10 | uM | 2 | 156.25 | 57.48 | 27.33 | 616.00 | 0.0448 | -0.1967 |
| MCF 10A | Omipalisib | 0.031623 | uM | 2 | 156.25 | 57.48 | 28.67 | 446.92 | 0.0647 | -0.2202 |