Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
Download: Excel (XLSX), Comma-separated (CSV)
Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | NVP-TAE684 | 10 | uM | 1 | 5000.00 | 2308.21 | 1180.33 | 2662.50 | 0.4454 | -0.9558 |
MCF 10A | Omipalisib | 1 | uM | 2 | 5000.00 | 3410.67 | 343.33 | 5991.17 | 0.0570 | -0.9387 |
MCF 10A | Omipalisib | 3.1623 | uM | 2 | 5000.00 | 3410.67 | 392.33 | 5991.17 | 0.0652 | -0.9284 |
MCF 10A | Omipalisib | 0.31623 | uM | 2 | 5000.00 | 3410.67 | 392.33 | 5991.17 | 0.0649 | -0.9264 |
Hs 578T | Nilotinib | 10 | uM | 1 | 5000.00 | 2308.21 | 1395.33 | 2662.50 | 0.5249 | -0.9120 |
Hs 578T | Nilotinib | 19.9526 | uM | 1 | 5000.00 | 2308.21 | 1443.00 | 2662.50 | 0.5430 | -0.8993 |
MCF 10A | Omipalisib | 0.1 | uM | 2 | 5000.00 | 3410.67 | 600.33 | 5991.17 | 0.1001 | -0.8813 |
Hs 578T | Etoposide | 10 | uM | 1 | 5000.00 | 2308.21 | 1539.67 | 2662.50 | 0.5792 | -0.8616 |
Hs 578T | Etoposide | 3.1623 | uM | 1 | 5000.00 | 2308.21 | 1573.33 | 2662.50 | 0.5924 | -0.8387 |
SK-BR-3 | Etoposide | 19.9526 | uM | 4 | 156.25 | 63.10 | 39.00 | 73.58 | 0.5278 | -0.8379 |
SK-BR-3 | Omipalisib | 3.1623 | uM | 3 | 5000.00 | 4101.40 | 1894.67 | 5695.67 | 0.3330 | -0.8015 |
Hs 578T | Etoposide | 19.9526 | uM | 1 | 5000.00 | 2308.21 | 1705.33 | 2662.50 | 0.6413 | -0.7700 |
SK-BR-3 | Omipalisib | 10 | uM | 3 | 5000.00 | 4101.40 | 2063.67 | 5695.67 | 0.3625 | -0.7660 |
SK-BR-3 | Taxol | 1 | uM | 3 | 5000.00 | 4101.40 | 2146.67 | 5695.67 | 0.3778 | -0.7482 |
SK-BR-3 | NVP-TAE684 | 3.1623 | uM | 4 | 156.25 | 63.10 | 44.67 | 73.58 | 0.6062 | -0.7477 |
Hs 578T | NVP-TAE684 | 3.1623 | uM | 1 | 5000.00 | 2308.21 | 1739.33 | 2662.50 | 0.6541 | -0.7473 |
SK-BR-3 | Omipalisib | 10 | uM | 4 | 156.25 | 63.10 | 38.00 | 81.08 | 0.4708 | -0.7437 |
SK-BR-3 | Taxol | 0.31623 | uM | 3 | 5000.00 | 4101.40 | 2175.67 | 5695.67 | 0.3820 | -0.7391 |
BT-20 | Omipalisib | 10 | uM | 4 | 156.25 | 44.67 | 16.00 | 75.92 | 0.2064 | -0.7336 |
SK-BR-3 | Taxol | 0.1 | uM | 3 | 5000.00 | 4101.40 | 2222.00 | 5695.67 | 0.3939 | -0.7290 |
SK-BR-3 | Omipalisib | 1 | uM | 3 | 5000.00 | 4101.40 | 2265.67 | 5695.67 | 0.3965 | -0.7103 |
SK-BR-3 | Taxol | 0.031623 | uM | 3 | 5000.00 | 4101.40 | 2315.67 | 5695.67 | 0.4096 | -0.7057 |
SK-BR-3 | NVP-TAE684 | 10 | uM | 4 | 156.25 | 63.10 | 46.67 | 73.58 | 0.6320 | -0.6945 |
BT-20 | Omipalisib | 3.1623 | uM | 4 | 156.25 | 44.67 | 20.33 | 75.92 | 0.2822 | -0.6815 |
MCF 10A | Omipalisib | 1 | uM | 2 | 2500.00 | 1446.42 | 109.67 | 7161.00 | 0.0153 | -0.6741 |