Breast Cancer Cell Density: Imaging assay of the density- and context-dependence of small molecule perturbagen response in breast cancer cell lines. Dataset 2 of 3: Mean cell count and mean normalized growth rate inhibition values across all replicates. - Dataset (ID:20257)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | Replicate | Seeding Density | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Linsitinib | 0.01 | uM | 8 | 2500.00 | 1235.42 | 12320.00 | 11579.92 | 1.0639 | 1.0387 |
| MCF 10A | Linsitinib | 0.01 | uM | 8 | 5000.00 | 1432.23 | 12203.00 | 11761.58 | 1.0376 | 1.0245 |
| MCF 10A | Lapatinib | 0.01 | uM | 8 | 5000.00 | 1432.23 | 12081.00 | 11761.58 | 1.0273 | 1.0178 |
| MCF 10A | 17-AAG | 0.0001 | uM | 8 | 5000.00 | 1432.23 | 12030.33 | 11761.58 | 1.0229 | 1.0149 |
| MCF 10A | 17-AAG | 0.001 | uM | 8 | 5000.00 | 1432.23 | 11992.67 | 11761.58 | 1.0197 | 1.0129 |
| MCF 10A | Linsitinib | 0.0033113 | uM | 8 | 5000.00 | 1432.23 | 11984.67 | 11761.58 | 1.0189 | 1.0123 |
| MCF 10A | 17-AAG | 0.000066069 | uM | 8 | 5000.00 | 1432.23 | 11968.33 | 11761.58 | 1.0176 | 1.0115 |
| MCF 10A | Lapatinib | 0.1 | uM | 8 | 2500.00 | 1235.42 | 11924.00 | 11579.92 | 1.0297 | 1.0182 |
| MCF 10A | 17-AAG | 0.000066069 | uM | 8 | 2500.00 | 1235.42 | 11920.67 | 11579.92 | 1.0294 | 1.0179 |
| MCF 10A | Linsitinib | 0.0033113 | uM | 8 | 2500.00 | 1235.42 | 11918.00 | 11579.92 | 1.0292 | 1.0179 |
| MCF 10A | Lapatinib | 0.031623 | uM | 8 | 5000.00 | 1432.23 | 11909.33 | 11761.58 | 1.0126 | 1.0083 |
| MCF 10A | Erlotinib | 0.1 | uM | 8 | 2500.00 | 1235.42 | 11902.67 | 11579.92 | 1.0279 | 1.0171 |
| MCF 10A | Lapatinib | 0.0033113 | uM | 8 | 5000.00 | 1432.23 | 11888.67 | 11761.58 | 1.0108 | 1.0069 |
| MCF 10A | Lapatinib | 0.0016596 | uM | 8 | 5000.00 | 1432.23 | 11870.00 | 11761.58 | 1.0091 | 1.0059 |
| MCF 10A | 17-AAG | 0.0001 | uM | 8 | 2500.00 | 1235.42 | 11855.33 | 11579.92 | 1.0238 | 1.0146 |
| MCF 10A | Linsitinib | 0.031623 | uM | 8 | 5000.00 | 1432.23 | 11847.33 | 11761.58 | 1.0074 | 1.0047 |
| MCF 10A | PLX-4720 | 10 | uM | 5 | 5000.00 | 2329.88 | 11847.00 | 9532.67 | 1.2428 | 1.2257 |
| MCF 10A | 17-AAG | 0.0031623 | uM | 8 | 5000.00 | 1432.23 | 11844.67 | 11761.58 | 1.0071 | 1.0046 |
| MCF 10A | PLX-4720 | 3.1623 | uM | 5 | 2500.00 | 2253.88 | 11835.00 | 10295.92 | 1.1497 | 1.1312 |
| MCF 10A | Lapatinib | 0.31623 | uM | 8 | 2500.00 | 1235.42 | 11828.33 | 11579.92 | 1.0215 | 1.0132 |
| MCF 10A | Linsitinib | 0.1 | uM | 8 | 5000.00 | 1432.23 | 11821.67 | 11761.58 | 1.0052 | 1.0034 |
| MCF 10A | PLX-4720 | 10 | uM | 5 | 2500.00 | 2253.88 | 11770.67 | 10295.92 | 1.1431 | 1.1255 |
| MCF 10A | Lapatinib | 0.0033113 | uM | 8 | 2500.00 | 1235.42 | 11755.00 | 11579.92 | 1.0151 | 1.0093 |
| MCF 10A | Lapatinib | 0.01 | uM | 8 | 2500.00 | 1235.42 | 11730.33 | 11579.92 | 1.0130 | 1.0079 |
| MCF 10A | 17-AAG | 0.000302 | uM | 8 | 5000.00 | 1432.23 | 11723.00 | 11761.58 | 0.9966 | 0.9977 |