LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SK-BR-3 | HG-6-64-01 | 0.04 | uM | LJP6 | 1 | M06 | 72 | hr | 2543 | 6251 | 5258 | 1.1887 | 1.3586 |
| MCF7 | HG-6-64-01 | 0.04 | uM | LJP6 | 1 | M06 | 72 | hr | 1389 | 6820 | 5147 | 1.3250 | 1.3212 |
| SK-BR-3 | Withaferin A | 0.04 | uM | LJP6 | 1 | G18 | 72 | hr | 2543 | 6093 | 5258 | 1.1586 | 1.3017 |
| SK-BR-3 | LJP6 | 1 | F11 | 72 | hr | 2543 | 6013 | 5258 | 1.1434 | 1.2728 | |||
| BT-20 | PD173074 | 3.33 | uM | LJP6 | 1 | I08 | 72 | hr | 1334 | 4823 | 3955 | 1.2192 | 1.2696 |
| SK-BR-3 | LJP6 | 1 | F12 | 72 | hr | 2543 | 5972 | 5258 | 1.1356 | 1.2580 | |||
| SK-BR-3 | LJP6 | 1 | F09 | 72 | hr | 2543 | 5952 | 5258 | 1.1318 | 1.2508 | |||
| Hs 578T | Sorafenib | 0.37 | uM | LJP6 | 3 | B10 | 72 | hr | 765 | 3850 | 3066 | 1.2557 | 1.2408 |
| BT-20 | Selumetinib | 0.04 | uM | LJP6 | 1 | M12 | 72 | hr | 1334 | 4726 | 3955 | 1.1947 | 1.2404 |
| MCF7 | Celastrol | 0.04 | uM | LJP6 | 1 | G12 | 72 | hr | 1389 | 6372 | 5147 | 1.2380 | 1.2392 |
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 2 | B09 | 72 | hr | 765 | 3882 | 3095 | 1.2540 | 1.2376 |
| SK-BR-3 | Selumetinib | 0.04 | uM | LJP6 | 1 | M12 | 72 | hr | 2543 | 5908 | 5258 | 1.1234 | 1.2349 |
| Hs 578T | Sorafenib | 1.11 | uM | LJP6 | 3 | B09 | 72 | hr | 765 | 3821 | 3066 | 1.2462 | 1.2324 |
| SK-BR-3 | Nilotinib | 0.12 | uM | LJP5 | 1 | N17 | 72 | hr | 2543 | 6520 | 5734 | 1.1370 | 1.2313 |
| SK-BR-3 | LJP6 | 1 | F08 | 72 | hr | 2543 | 5894 | 5258 | 1.1208 | 1.2299 | |||
| Hs 578T | SB590885 | 3.33 | uM | LJP5 | 3 | L14 | 72 | hr | 765 | 3935 | 3152 | 1.2482 | 1.2293 |
| SK-BR-3 | LJP6 | 1 | F07 | 72 | hr | 2543 | 5877 | 5258 | 1.1175 | 1.2237 | |||
| SK-BR-3 | LJP6 | 2 | F11 | 72 | hr | 2543 | 6100 | 5438 | 1.1217 | 1.2209 | |||
| SK-BR-3 | HG-6-64-01 | 0.12 | uM | LJP6 | 1 | M05 | 72 | hr | 2543 | 5865 | 5258 | 1.1153 | 1.2194 |
| MCF7 | LJP6 | 1 | F08 | 72 | hr | 1389 | 6258 | 5147 | 1.2158 | 1.2179 | |||
| Hs 578T | SB590885 | 0.12 | uM | LJP5 | 2 | L17 | 72 | hr | 765 | 3890 | 3151 | 1.2343 | 1.2171 |
| Hs 578T | PLX-4720 | 0.37 | uM | LJP5 | 2 | K04 | 72 | hr | 765 | 3881 | 3151 | 1.2314 | 1.2146 |
| BT-20 | HG-6-64-01 | 0.37 | uM | LJP6 | 1 | M04 | 72 | hr | 1334 | 4637 | 3955 | 1.1722 | 1.2134 |
| Hs 578T | SB590885 | 0.04 | uM | LJP5 | 1 | L18 | 72 | hr | 765 | 3860 | 3140 | 1.2292 | 1.2132 |
| SK-BR-3 | LJP6 | 2 | F12 | 72 | hr | 2543 | 6077 | 5438 | 1.1175 | 1.2132 |