LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 1 | J06 | 72 | hr | 1389 | 5915 | 5772 | 1.0247 | 1.0239 |
| MCF7 | Seliciclib | 0.04 | uM | LJP5 | 3 | J06 | 72 | hr | 1389 | 6077 | 6038 | 1.0064 | 1.0060 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 1 | J05 | 72 | hr | 1389 | 5825 | 5772 | 1.0091 | 1.0088 |
| MCF7 | Seliciclib | 0.12 | uM | LJP5 | 3 | J05 | 72 | hr | 1389 | 6115 | 6038 | 1.0127 | 1.0119 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 1 | J04 | 72 | hr | 1389 | 5231 | 5772 | 0.9062 | 0.9064 |
| MCF7 | Seliciclib | 0.37 | uM | LJP5 | 3 | J04 | 72 | hr | 1389 | 6206 | 6038 | 1.0277 | 1.0260 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 1 | J03 | 72 | hr | 1389 | 4974 | 5772 | 0.8617 | 0.8602 |
| MCF7 | Seliciclib | 1.11 | uM | LJP5 | 3 | J03 | 72 | hr | 1389 | 5578 | 6038 | 0.9237 | 0.9266 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 1 | J02 | 72 | hr | 1389 | 4584 | 5772 | 0.7941 | 0.7878 |
| MCF7 | Seliciclib | 3.33 | uM | LJP5 | 3 | J02 | 72 | hr | 1389 | 5104 | 6038 | 0.8452 | 0.8475 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 1 | J01 | 72 | hr | 1389 | 1149 | 5772 | 0.1991 | -0.0882 |
| MCF7 | Seliciclib | 10 | uM | LJP5 | 3 | J01 | 72 | hr | 1389 | 1407 | 6038 | 0.2330 | 0.0061 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 1 | K06 | 72 | hr | 1389 | 5493 | 5147 | 1.0672 | 1.0700 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 2 | K06 | 72 | hr | 1389 | 5687 | 5447 | 1.0439 | 1.0440 |
| MCF7 | AT-7519 | 0.04 | uM | LJP6 | 3 | K06 | 72 | hr | 1389 | 5080 | 5740 | 0.8849 | 0.8841 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 1 | K05 | 72 | hr | 1389 | 2594 | 5147 | 0.5040 | 0.3917 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 2 | K05 | 72 | hr | 1389 | 2336 | 5447 | 0.4288 | 0.3017 |
| MCF7 | AT-7519 | 0.12 | uM | LJP6 | 3 | K05 | 72 | hr | 1389 | 2662 | 5740 | 0.4637 | 0.3740 |
| MCF7 | AT-7519 | 0.37 | uM | LJP6 | 1 | K04 | 72 | hr | 1389 | 730 | 5147 | 0.1418 | -0.2886 |
| MCF7 | AT-7519 | 0.37 | uM | LJP6 | 2 | K04 | 72 | hr | 1389 | 747 | 5447 | 0.1371 | -0.2699 |
| MCF7 | AT-7519 | 0.37 | uM | LJP6 | 3 | K04 | 72 | hr | 1389 | 790 | 5740 | 0.1376 | -0.2410 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 1 | K03 | 72 | hr | 1389 | 576 | 5147 | 0.1119 | -0.3724 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 2 | K03 | 72 | hr | 1389 | 445 | 5447 | 0.0817 | -0.4386 |
| MCF7 | AT-7519 | 1.11 | uM | LJP6 | 3 | K03 | 72 | hr | 1389 | 640 | 5740 | 0.1115 | -0.3152 |
| MCF7 | AT-7519 | 3.33 | uM | LJP6 | 1 | K02 | 72 | hr | 1389 | 542 | 5147 | 0.1053 | -0.3923 |