LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)
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| Cell | Small Molecule | Small Mol Concentration | Small Mol Conc Unit | LJP Library Plate | Replicate | Assay Well | Timepoint | Timepoint Unit | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 1694 | 99 | 11220 | 0.0088 | -0.6470 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 2 | H07 | 72 | hr | 1694 | 106 | 11309 | 0.0094 | -0.6365 |
| Hs 578T | HG-6-64-01 | 10 | uM | LJP6 | 1 | M01 | 72 | hr | 765 | 123 | 3143 | 0.0391 | -0.5920 |
| MCF 10A | Canertinib | 10 | uM | LJP6 | 3 | H07 | 72 | hr | 1694 | 142 | 11121 | 0.0128 | -0.5988 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP6 | 3 | C19 | 72 | hr | 765 | 163 | 3066 | 0.0532 | -0.5379 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 2 | C19 | 72 | hr | 765 | 165 | 3151 | 0.0524 | -0.5281 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP6 | 1 | C20 | 72 | hr | 765 | 170 | 3143 | 0.0541 | -0.5218 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 3 | C19 | 72 | hr | 765 | 174 | 3152 | 0.0552 | -0.5156 |
| Hs 578T | Mitoxantrone | 10 | uM | LJP5 | 1 | C19 | 72 | hr | 765 | 177 | 3140 | 0.0564 | -0.5125 |
| Hs 578T | AT-7519 | 10 | uM | LJP6 | 1 | K01 | 72 | hr | 765 | 179 | 3143 | 0.0569 | -0.5096 |
| Hs 578T | CGP60474 | 10 | uM | LJP6 | 1 | G01 | 72 | hr | 765 | 182 | 3143 | 0.0579 | -0.5055 |
| BT-20 | CGP60474 | 10 | uM | LJP6 | 1 | G01 | 72 | hr | 1334 | 182 | 3955 | 0.0460 | -0.7195 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP5 | 1 | C20 | 72 | hr | 765 | 186 | 3140 | 0.0592 | -0.5005 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP5 | 3 | C20 | 72 | hr | 765 | 186 | 3152 | 0.0590 | -0.4996 |
| MCF 10A | LDN-193189 | 10 | uM | LJP5 | 1 | G01 | 72 | hr | 1694 | 192 | 11042 | 0.0174 | -0.5530 |
| Hs 578T | HG-6-64-01 | 10 | uM | LJP6 | 3 | M01 | 72 | hr | 765 | 196 | 3066 | 0.0639 | -0.4934 |
| Hs 578T | Mitoxantrone | 3.33 | uM | LJP5 | 2 | C20 | 72 | hr | 765 | 196 | 3151 | 0.0622 | -0.4866 |
| MCF 10A | CGP60474 | 3.33 | uM | LJP6 | 1 | G02 | 72 | hr | 1694 | 197 | 11220 | 0.0176 | -0.5457 |
| Hs 578T | LDN-193189 | 10 | uM | LJP5 | 3 | G01 | 72 | hr | 765 | 197 | 3152 | 0.0625 | -0.4853 |
| Hs 578T | HG-6-64-01 | 10 | uM | LJP6 | 2 | M01 | 72 | hr | 765 | 205 | 3095 | 0.0662 | -0.4795 |
| MCF 10A | AT-7519 | 10 | uM | LJP6 | 3 | K01 | 72 | hr | 1694 | 205 | 11121 | 0.0184 | -0.5407 |
| Hs 578T | CGP60474 | 10 | uM | LJP6 | 2 | G01 | 72 | hr | 765 | 209 | 3095 | 0.0675 | -0.4745 |
| Hs 578T | Canertinib | 10 | uM | LJP6 | 1 | H07 | 72 | hr | 765 | 214 | 3143 | 0.0681 | -0.4647 |
| MCF 10A | Alvocidib | 1.11 | uM | LJP6 | 1 | A15 | 72 | hr | 1694 | 215 | 11220 | 0.0192 | -0.5309 |
| Hs 578T | WH-4-025 | 10 | uM | LJP5 | 3 | O07 | 72 | hr | 765 | 218 | 3152 | 0.0692 | -0.4591 |