LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset - HMS LINCS Database

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)

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Small molecules	Cells

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Cell	Small Molecule	Small Mol Concentration	Small Mol Conc Unit	LJP Library Plate	Replicate	Assay Well	Timepoint	Timepoint Unit	Total Cell Count Before Treatment	Total Cell Count After Treatment	Total Control Cell Count	Relative Cell Count	Normalized Growth Rate Inhibition Value
BT-20	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	1334	3174	3955	0.8024	0.7379
BT-20	Trametinib	0.04	uM	LJP5	3	P24	72	hr	1334	3431	4117	0.8332	0.7877
MDA-MB-231	Trametinib	0.04	uM	LJP5	1	P24	72	hr	1311	1530	5128	0.2983	0.0814
MDA-MB-231	Trametinib	0.04	uM	LJP5	3	P24	72	hr	1311	1672	5010	0.3337	0.1337
BT-20	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	1334	3303	3899	0.8471	0.7966
BT-20	Trametinib	0.04	uM	LJP5	2	P24	72	hr	1334	2925	4051	0.7220	0.6320
MDA-MB-231	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	1311	3936	4961	0.7933	0.7727
MDA-MB-231	XMD11-85h	0.04	uM	LJP6	3	P24	72	hr	1311	3785	4973	0.7610	0.7352
SK-BR-3	Trametinib	0.04	uM	LJP5	2	P24	72	hr	2543	3447	5761	0.5983	0.2939
MDA-MB-231	Trametinib	0.04	uM	LJP5	2	P24	72	hr	1311	1592	5100	0.3122	0.1039
MDA-MB-231	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	1311	3724	4870	0.7647	0.7356
MCF7	Trametinib	0.04	uM	LJP5	3	P24	72	hr	1389	2744	6038	0.4544	0.3787
BT-20	XMD11-85h	0.04	uM	LJP6	3	P24	72	hr	1334	3623	3921	0.9239	0.9008
BT-20	Trametinib	0.04	uM	LJP5	1	P24	72	hr	1334	3109	3930	0.7909	0.7205
SK-BR-3	Trametinib	0.04	uM	LJP5	3	P24	72	hr	2543	4204	5760	0.7298	0.5312
MCF7	Trametinib	0.04	uM	LJP5	1	P24	72	hr	1389	2625	5772	0.4547	0.3630
SK-BR-3	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	2543	4083	5258	0.7764	0.5709
MCF7	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	1389	3116	5147	0.6054	0.5335
SK-BR-3	XMD11-85h	0.04	uM	LJP6	3	P24	72	hr	2543	3925	5557	0.7063	0.4692
SK-BR-3	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	2543	4127	5438	0.7589	0.5550
SK-BR-3	Trametinib	0.04	uM	LJP5	1	P24	72	hr	2543	3405	5734	0.5938	0.2824
MCF7	XMD11-85h	0.04	uM	LJP6	3	P24	72	hr	1389	4594	5740	0.8003	0.7938
MCF7	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	1389	4033	5447	0.7403	0.7171
Hs 578T	XMD11-85h	0.04	uM	LJP6	2	P24	72	hr	765	3090	3095	0.9982	0.9982
Hs 578T	XMD11-85h	0.04	uM	LJP6	1	P24	72	hr	765	3100	3143	0.9861	0.9863

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HMS LINCS Project

LINCS Pilot Phase Joint Project: Sensitivity measures of six breast cancer cell lines to a library of small molecule kinase inhibitors (single drug treatments). Dataset 9 of 15: Cell count and normalized growth rate inhibition values within biological replicate 2. - Dataset (ID:20246)