High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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| Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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| BT-20 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 219 | 745 | | 5417 | 7682 | 459.9 | 105.22 | 163.49 | 154.87 | 337 | 370 | 397 | 421 | 446 | 473 | 502 | 541 | 606 | 0.1009 | 775 | 0.952 | 103.82 | 28.00 | 1 | 0.0462 | 250 | 0.0007 | 65.25 | 7.472 | 0.1512 | 222541.0 | 113000000 | 60600000000 | 34000000000000 | 0.4352 | 0.2219 | 0.0006 | 0.0000 | 0.0009 | 0.0002 | 0.0012 | 0.0002 | 0.0160 | 0.0018 | 0.0690 | 0.0207 | 0.1406 | 0.0417 | 0.1432 | 0.0435 | 0.1788 | 0.0688 | 0.4498 | 0.8231 | 0.0005 | 0.0000 | 0.0002 | 0.0000 | 0.0005 | 0.0000 | 0.0073 | 0.0006 | 0.0381 | 0.0131 | 0.0709 | 0.0252 | 0.0628 | 0.0204 | 0.0986 | 0.0385 | 0.7212 | 0.9023 | 0.0061 | 0.0059 | 0.0163 | 0.0088 | 0.0132 | 0.0147 | 0.0499 | 0.1003 | 0.0957 | 0.1504 | 0.1232 | 0.1681 | 0.0896 | 0.1386 | 0.0998 | 0.1534 | 0.5061 | 0.2596 | 0.0016 | 0.0041 | 0.0086 | 0.0345 | 0.0858 | 0.1248 | 0.0998 | 0.1281 | 0.5127 | 16 | 24 | 47 | 80 | 120 | 162 | 209 | 275 | 401 | 0.0119 | 39.04 | 6.336 | 0.3337 | 50710.0 | 20800000 | 10000000000 | 5380000000000 | 0.5608 | 0.1109 | 0.0360 | 0.0009 | 0.1274 | 0.0147 | 0.1801 | 0.0477 | 0.1670 | 0.1198 | 0.1511 | 0.1590 | 0.1292 | 0.1862 | 0.1002 | 0.1203 | 0.0712 | 0.1323 | 0.0378 | 0.2192 | 0.0008 | 0.0002 | 0.0011 | 0.0005 | 0.0016 | 0.0021 | 0.0153 | 0.0143 | 0.0629 | 0.0509 | 0.1018 | 0.0835 | 0.0862 | 0.0685 | 0.1314 | 0.1042 | 0.5988 | 0.6757 | 0.0020 | 0.0020 | 0.0016 | 0.0045 | 0.0115 | 0.0109 | 0.0262 | 0.0377 | 0.0994 | 0.0942 | 0.1224 | 0.1413 | 0.0970 | 0.0932 | 0.1431 | 0.1413 | 0.4968 | 0.4750 | 0.0000 | 0.0010 | 0.0056 | 0.0203 | 0.0811 | 0.1353 | 0.0889 | 0.1366 | 0.5312 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 232 | 638 | | 6254 | 5949 | 114.7 | 25.41 | 187.62 | 143.24 | 87 | 94 | 100 | 105 | 110 | 116 | 123 | 132 | 150 | 0.1308 | 778 | 0.961 | 106.23 | 31.32 | 1 | 0.0421 | 263 | 0.0034 | 14.14 | 6.046 | 0.2876 | 13792.0 | 1750000 | 233000000 | 32800000000 | 0.4648 | 0.1869 | 0.0000 | 0.0000 | 0.0021 | 0.0000 | 0.0092 | 0.0003 | 0.0230 | 0.0024 | 0.0653 | 0.0177 | 0.1219 | 0.0491 | 0.1387 | 0.0346 | 0.1702 | 0.0694 | 0.4696 | 0.8265 | 0.0000 | 0.0000 | 0.0013 | 0.0000 | 0.0021 | 0.0000 | 0.0088 | 0.0003 | 0.0324 | 0.0105 | 0.0605 | 0.0277 | 0.0714 | 0.0137 | 0.0961 | 0.0290 | 0.7274 | 0.9189 | 0.0097 | 0.0198 | 0.0117 | 0.0074 | 0.0272 | 0.0272 | 0.0690 | 0.0743 | 0.1370 | 0.2030 | 0.1594 | 0.1807 | 0.1108 | 0.1436 | 0.1429 | 0.1337 | 0.3324 | 0.2104 | 0.0023 | 0.0109 | 0.0214 | 0.0436 | 0.1019 | 0.1320 | 0.1169 | 0.1421 | 0.4289 | 42 | 65 | 88 | 115 | 148 | 183 | 233 | 303 | 394 | 0.0021 | 69.90 | 6.913 | 0.2582 | 55713.5 | 21700000 | 10100000000 | 5300000000000 | 0.5779 | 0.0961 | 0.0346 | 0.0023 | 0.1508 | 0.0121 | 0.2315 | 0.0680 | 0.1585 | 0.1253 | 0.1537 | 0.1524 | 0.1162 | 0.1729 | 0.0836 | 0.1356 | 0.0500 | 0.1212 | 0.0211 | 0.2102 | 0.0017 | 0.0003 | 0.0017 | 0.0017 | 0.0069 | 0.0050 | 0.0247 | 0.0182 | 0.0897 | 0.0636 | 0.1357 | 0.1151 | 0.1103 | 0.0851 | 0.1454 | 0.1258 | 0.4838 | 0.5854 | 0.0016 | 0.0047 | 0.0064 | 0.0034 | 0.0112 | 0.0229 | 0.0508 | 0.0518 | 0.1086 | 0.1312 | 0.1825 | 0.1783 | 0.1215 | 0.1285 | 0.1429 | 0.1406 | 0.3745 | 0.3385 | 0.0004 | 0.0017 | 0.0120 | 0.0322 | 0.1043 | 0.1550 | 0.1245 | 0.1426 | 0.4272 |
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 456 | 893 | | 7298 | 7323 | 187.1 | 41.22 | 216.83 | 133.57 | 140 | 153 | 163 | 172 | 181 | 191 | 203 | 217 | 241 | 0.1269 | 929 | 1.120 | 100.70 | 34.44 | 2 | 0.0340 | 248 | 0.0013 | 39.38 | 6.942 | 0.1916 | 36690.8 | 7560000 | 1640000000 | 376000000000 | 0.4324 | 0.2088 | 0.0002 | 0.0000 | 0.0004 | 0.0000 | 0.0047 | 0.0003 | 0.0179 | 0.0010 | 0.0803 | 0.0227 | 0.1350 | 0.0383 | 0.1477 | 0.0424 | 0.1875 | 0.0685 | 0.4263 | 0.8267 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0059 | 0.0001 | 0.0393 | 0.0136 | 0.0647 | 0.0208 | 0.0718 | 0.0167 | 0.1034 | 0.0300 | 0.7137 | 0.9187 | 0.0101 | 0.0100 | 0.0135 | 0.0376 | 0.0262 | 0.0526 | 0.0760 | 0.1153 | 0.1529 | 0.1980 | 0.1782 | 0.1930 | 0.1275 | 0.1454 | 0.1579 | 0.1103 | 0.2576 | 0.1378 | 0.0021 | 0.0043 | 0.0092 | 0.0374 | 0.0860 | 0.1310 | 0.1127 | 0.1396 | 0.4776 | 63 | 92 | 126 | 158 | 191 | 228 | 275 | 332 | 409 | 0.0011 | 78.81 | 7.283 | 0.1845 | 64856.6 | 23800000 | 10100000000 | 4840000000000 | 0.5256 | 0.1334 | 0.0183 | 0.0013 | 0.0889 | 0.0097 | 0.2296 | 0.0405 | 0.1967 | 0.0866 | 0.1778 | 0.1704 | 0.1364 | 0.2228 | 0.0944 | 0.1556 | 0.0384 | 0.1403 | 0.0195 | 0.1729 | 0.0015 | 0.0002 | 0.0025 | 0.0028 | 0.0091 | 0.0054 | 0.0269 | 0.0191 | 0.0793 | 0.0611 | 0.1299 | 0.1025 | 0.1089 | 0.0860 | 0.1316 | 0.1112 | 0.5104 | 0.6118 | 0.0033 | 0.0033 | 0.0066 | 0.0076 | 0.0166 | 0.0239 | 0.0439 | 0.0631 | 0.1159 | 0.1430 | 0.1718 | 0.1816 | 0.1308 | 0.1294 | 0.1320 | 0.1457 | 0.3791 | 0.3023 | 0.0009 | 0.0060 | 0.0160 | 0.0393 | 0.0978 | 0.1494 | 0.1142 | 0.1324 | 0.4439 |
| SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 758 | 118 | | 3722 | 7678 | 368.8 | 182.51 | 164.24 | 272.94 | 145 | 178 | 217 | 266 | 351 | 446 | 510 | 563 | 614 | 0.0847 | 650 | 1.108 | 87.24 | 31.58 | 2 | 0.0623 | 232 | 0.0018 | 10.54 | 6.623 | 0.3115 | 169332.0 | 88000000 | 48900000000 | 28300000000000 | 0.2899 | 0.3386 | 0.0000 | 0.0007 | 0.0000 | 0.0027 | 0.0086 | 0.0047 | 0.0310 | 0.0167 | 0.1480 | 0.0670 | 0.2220 | 0.0965 | 0.1463 | 0.0810 | 0.1911 | 0.1186 | 0.2530 | 0.6122 | 0.0000 | 0.0000 | 0.0000 | 0.0008 | 0.0010 | 0.0020 | 0.0029 | 0.0035 | 0.0201 | 0.0203 | 0.0315 | 0.0250 | 0.0220 | 0.0238 | 0.0382 | 0.0355 | 0.8844 | 0.8892 | 0.0000 | 0.0009 | 0.0000 | 0.0009 | 0.0000 | 0.0019 | 0.0066 | 0.0149 | 0.0238 | 0.0411 | 0.0416 | 0.0747 | 0.0350 | 0.0691 | 0.0430 | 0.0756 | 0.8500 | 0.7208 | 0.0000 | 0.0000 | 0.0006 | 0.0017 | 0.0251 | 0.0345 | 0.0239 | 0.0395 | 0.8747 | 12 | 17 | 22 | 28 | 43 | 72 | 114 | 240 | 499 | 0.0621 | 27.12 | 4.594 | 0.6002 | 101458.0 | 93500000 | 101000000000 | 118000000000000 | 0.3873 | 0.2579 | 0.0278 | 0.0021 | 0.0732 | 0.0103 | 0.1995 | 0.0372 | 0.1692 | 0.0702 | 0.1843 | 0.1569 | 0.1162 | 0.1610 | 0.0909 | 0.1352 | 0.0707 | 0.1197 | 0.0682 | 0.3075 | 0.0019 | 0.0000 | 0.0014 | 0.0028 | 0.0053 | 0.0035 | 0.0101 | 0.0102 | 0.0483 | 0.0501 | 0.0718 | 0.0654 | 0.0565 | 0.0556 | 0.0775 | 0.0832 | 0.7271 | 0.7292 | 0.0000 | 0.0006 | 0.0041 | 0.0006 | 0.0053 | 0.0026 | 0.0077 | 0.0057 | 0.0543 | 0.0529 | 0.0721 | 0.0861 | 0.0543 | 0.0529 | 0.0874 | 0.0848 | 0.7147 | 0.7136 | 0.0005 | 0.0027 | 0.0086 | 0.0065 | 0.0507 | 0.0706 | 0.0507 | 0.0841 | 0.7256 | ||
| BT-20 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 645 | 729 | | 1042 | 10329 | 562.4 | 153.48 | 8.59 | 2.99 | 395 | 423 | 449 | 479 | 518 | 570 | 632 | 713 | 801 | 0.0578 | 597 | 0.406 | 38.95 | 6.00 | 1 | 0.1344 | 140 | 0.0020 | 28.18 | 6.374 | 0.1954 | 339826.0 | 220000000 | 152000000000 | 110000000000000 | 0.4086 | 0.2249 | 0.0000 | 0.0011 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0212 | 0.0033 | 0.1017 | 0.0499 | 0.1737 | 0.0684 | 0.1504 | 0.0543 | 0.1822 | 0.0934 | 0.3708 | 0.7296 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0123 | 0.0010 | 0.0412 | 0.0345 | 0.0686 | 0.0432 | 0.0521 | 0.0288 | 0.0782 | 0.0518 | 0.7476 | 0.8407 | 0.0000 | 0.0083 | 0.0000 | 0.0000 | 0.0000 | 0.0248 | 0.0311 | 0.0496 | 0.0778 | 0.0992 | 0.1051 | 0.1157 | 0.0856 | 0.1074 | 0.0895 | 0.0992 | 0.6109 | 0.4959 | 0.0000 | 0.0000 | 0.0000 | 0.0094 | 0.0587 | 0.0915 | 0.0493 | 0.0822 | 0.7089 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 11 | 13 | 0.0126 | 8.42 | 4.763 | 0.3488 | 82.8 | 880.135 | 10198.1 | 127270 | 0.4495 | 0.1810 | 0.0600 | 0.0013 | 0.1168 | 0.0074 | 0.1774 | 0.0227 | 0.2182 | 0.0459 | 0.2039 | 0.0693 | 0.1400 | 0.1259 | 0.0611 | 0.1879 | 0.0197 | 0.2819 | 0.0029 | 0.2578 | 0.0209 | 0.0001 | 0.0384 | 0.0037 | 0.0525 | 0.0120 | 0.0714 | 0.0250 | 0.0846 | 0.0391 | 0.1058 | 0.0659 | 0.1247 | 0.1005 | 0.1743 | 0.1835 | 0.3273 | 0.5701 | 0.0655 | 0.0973 | 0.0800 | 0.1227 | 0.0883 | 0.1578 | 0.1065 | 0.1446 | 0.1242 | 0.1437 | 0.1356 | 0.1420 | 0.1479 | 0.1060 | 0.1487 | 0.0640 | 0.1033 | 0.0219 | 0.0340 | 0.0642 | 0.0722 | 0.0754 | 0.0867 | 0.1099 | 0.1315 | 0.1726 | 0.2535 |
| SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 400 | 407 | | 6276 | 11399 | 375.7 | 86.02 | 140.41 | 164.45 | 245 | 323 | 357 | 378 | 396 | 413 | 428 | 444 | 463 | 0.0798 | 910 | 1.138 | 23.43 | 8.49 | 5 | 0.0099 | 62 | 0.0020 | 19.90 | 6.638 | 0.2782 | 148520.0 | 60600000 | 25300000000 | 10700000000000 | 0.3938 | 0.2401 | 0.0005 | 0.0000 | 0.0014 | 0.0000 | 0.0021 | 0.0000 | 0.0137 | 0.0000 | 0.0354 | 0.0108 | 0.0722 | 0.0252 | 0.0748 | 0.0104 | 0.1107 | 0.0183 | 0.6891 | 0.9352 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0137 | 0.0108 | 0.0298 | 0.0252 | 0.0216 | 0.0104 | 0.0319 | 0.0169 | 0.9017 | 0.9367 | 0.0072 | 1.0000 | 0.0184 | 0.0000 | 0.0419 | 0.0000 | 0.0593 | 0.0000 | 0.0992 | 0.0000 | 0.1329 | 0.0000 | 0.1299 | 0.0000 | 0.1227 | 0.0000 | 0.3885 | 0.0000 | 0.0000 | 0.0010 | 0.0031 | 0.0067 | 0.0347 | 0.0601 | 0.0515 | 0.0772 | 0.7656 | 9 | 11 | 15 | 29 | 67 | 119 | 185 | 272 | 389 | 0.0593 | 7.25 | 4.451 | 0.5348 | 46754.1 | 20300000 | 10200000000 | 5650000000000 | 0.4511 | 0.1880 | 0.0237 | 0.0010 | 0.1225 | 0.0110 | 0.2381 | 0.0628 | 0.1729 | 0.1187 | 0.1275 | 0.1830 | 0.1265 | 0.1945 | 0.0810 | 0.1237 | 0.0632 | 0.1062 | 0.0445 | 0.1990 | 0.0000 | 0.0000 | 0.0008 | 0.0002 | 0.0017 | 0.0009 | 0.0089 | 0.0072 | 0.0450 | 0.0402 | 0.0820 | 0.0693 | 0.0542 | 0.0504 | 0.0858 | 0.0775 | 0.7214 | 0.7543 | 0.0003 | 0.0003 | 0.0030 | 0.0015 | 0.0041 | 0.0034 | 0.0160 | 0.0153 | 0.0574 | 0.0644 | 0.0907 | 0.1103 | 0.0655 | 0.0754 | 0.1045 | 0.1051 | 0.6586 | 0.6243 | 0.0002 | 0.0002 | 0.0019 | 0.0112 | 0.0594 | 0.0827 | 0.0622 | 0.0946 | 0.6875 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 1013 | 682 | | 13732 | 29163 | 489.2 | 88.51 | 64.45 | 140.69 | 369 | 416 | 448 | 471 | 492 | 513 | 535 | 561 | 598 | 0.0441 | 1286 | 0.817 | 91.92 | 19.24 | 13 | 0.0163 | 224 | 0.0009 | 42.91 | 7.350 | 0.2018 | 247158.0 | 129000000 | 68600000000 | 37500000000000 | 0.4764 | 0.1806 | 0.0003 | 0.0000 | 0.0008 | 0.0000 | 0.0010 | 0.0002 | 0.0078 | 0.0008 | 0.0407 | 0.0122 | 0.0790 | 0.0262 | 0.0719 | 0.0181 | 0.1073 | 0.0285 | 0.6912 | 0.9139 | 0.0000 | 0.0000 | 0.0002 | 0.0000 | 0.0001 | 0.0000 | 0.0022 | 0.0004 | 0.0199 | 0.0104 | 0.0412 | 0.0212 | 0.0321 | 0.0132 | 0.0499 | 0.0202 | 0.8544 | 0.9345 | 0.0040 | 0.0187 | 0.0103 | 0.0327 | 0.0343 | 0.0467 | 0.0623 | 0.0561 | 0.1189 | 0.1402 | 0.1320 | 0.2150 | 0.0971 | 0.1122 | 0.1223 | 0.1636 | 0.4189 | 0.2150 | 0.0010 | 0.0013 | 0.0046 | 0.0192 | 0.0608 | 0.1022 | 0.0895 | 0.1194 | 0.6020 | 6 | 7 | 9 | 10 | 11 | 13 | 21 | 61 | 192 | 0.2959 | 12.61 | 3.087 | 0.7489 | 23946.5 | 14200000 | 10300000000 | 8680000000000 | 0.5403 | 0.1285 | 0.0409 | 0.0032 | 0.1110 | 0.0290 | 0.1519 | 0.0767 | 0.1548 | 0.0965 | 0.1500 | 0.1282 | 0.1519 | 0.1650 | 0.1042 | 0.1195 | 0.0828 | 0.1232 | 0.0526 | 0.2587 | 0.0003 | 0.0007 | 0.0006 | 0.0010 | 0.0021 | 0.0026 | 0.0106 | 0.0112 | 0.0421 | 0.0350 | 0.0683 | 0.0631 | 0.0405 | 0.0400 | 0.0644 | 0.0618 | 0.7712 | 0.7846 | 0.0002 | 0.0000 | 0.0013 | 0.0008 | 0.0025 | 0.0025 | 0.0115 | 0.0135 | 0.0507 | 0.0532 | 0.0788 | 0.0824 | 0.0465 | 0.0475 | 0.0710 | 0.0731 | 0.7375 | 0.7270 | 0.0007 | 0.0010 | 0.0017 | 0.0150 | 0.0416 | 0.0733 | 0.0472 | 0.0663 | 0.7529 |
| MCF 10A | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 309 | 735 | | 1819 | 14901 | 73.2 | 15.19 | 136.21 | 157.45 | 56 | 62 | 65 | 67 | 70 | 74 | 79 | 85 | 94 | 0.0571 | 851 | 0.961 | 66.85 | 20.22 | 3 | 0.0995 | 181 | 0.0042 | 13.83 | 5.799 | 0.2858 | 5584.7 | 444991 | 37000000 | 3220000000 | 0.5015 | 0.1554 | 0.0008 | 0.0000 | 0.0047 | 0.0006 | 0.0228 | 0.0012 | 0.0417 | 0.0140 | 0.1133 | 0.0450 | 0.1707 | 0.1040 | 0.1526 | 0.0900 | 0.1794 | 0.1244 | 0.3139 | 0.6209 | 0.0000 | 0.0000 | 0.0013 | 0.0006 | 0.0069 | 0.0011 | 0.0202 | 0.0117 | 0.0656 | 0.0362 | 0.1040 | 0.0841 | 0.0807 | 0.0523 | 0.1230 | 0.0885 | 0.5984 | 0.7255 | 0.0095 | 0.0238 | 0.0063 | 0.0357 | 0.0381 | 0.1190 | 0.1175 | 0.2381 | 0.1460 | 0.1905 | 0.2190 | 0.1429 | 0.1238 | 0.0833 | 0.1143 | 0.0833 | 0.2254 | 0.0833 | 0.0025 | 0.0135 | 0.0197 | 0.0492 | 0.1095 | 0.1365 | 0.1267 | 0.1501 | 0.3924 | 14 | 17 | 23 | 40 | 73 | 110 | 160 | 243 | 367 | 0.0319 | 18.03 | 5.311 | 0.4923 | 43340.4 | 19300000 | 10300000000 | 6180000000000 | 0.4512 | 0.1992 | 0.0348 | 0.0006 | 0.1211 | 0.0135 | 0.2124 | 0.0737 | 0.1696 | 0.0995 | 0.1621 | 0.1575 | 0.1286 | 0.1894 | 0.0776 | 0.1317 | 0.0547 | 0.1357 | 0.0391 | 0.1983 | 0.0008 | 0.0000 | 0.0012 | 0.0006 | 0.0050 | 0.0021 | 0.0163 | 0.0107 | 0.0553 | 0.0478 | 0.0947 | 0.0811 | 0.0696 | 0.0552 | 0.0962 | 0.0929 | 0.6610 | 0.7096 | 0.0009 | 0.0008 | 0.0018 | 0.0024 | 0.0075 | 0.0050 | 0.0218 | 0.0214 | 0.0693 | 0.0833 | 0.1160 | 0.1303 | 0.0869 | 0.0844 | 0.1141 | 0.1295 | 0.5816 | 0.5430 | 0.0008 | 0.0010 | 0.0031 | 0.0189 | 0.0617 | 0.1060 | 0.0742 | 0.1094 | 0.6249 |
| MCF7 | Barasertib | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 15 | 1 | 234 | 799 | | 13982 | 47347 | 267.6 | 72.72 | 111.48 | 151.15 | 180 | 206 | 227 | 244 | 261 | 277 | 298 | 324 | 366 | 0.0290 | 1375 | 0.637 | 134.38 | 29.41 | 4 | 0.0255 | 356 | 0.0013 | 25.91 | 6.963 | 0.2170 | 76872.3 | 23600000 | 7750000000 | 2700000000000 | 0.4326 | 0.2214 | 0.0001 | 0.0000 | 0.0013 | 0.0001 | 0.0055 | 0.0004 | 0.0221 | 0.0029 | 0.0806 | 0.0231 | 0.1501 | 0.0550 | 0.1533 | 0.0526 | 0.1827 | 0.0775 | 0.4043 | 0.7885 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0018 | 0.0002 | 0.0076 | 0.0010 | 0.0363 | 0.0137 | 0.0660 | 0.0277 | 0.0623 | 0.0230 | 0.0865 | 0.0394 | 0.7392 | 0.8952 | 0.0052 | 0.0034 | 0.0097 | 0.0101 | 0.0207 | 0.0151 | 0.0446 | 0.0772 | 0.1034 | 0.1394 | 0.1383 | 0.2065 | 0.0906 | 0.0999 | 0.1317 | 0.1360 | 0.4557 | 0.3123 | 0.0005 | 0.0028 | 0.0097 | 0.0328 | 0.0738 | 0.1215 | 0.0977 | 0.1158 | 0.5454 | 7 | 9 | 11 | 16 | 39 | 79 | 133 | 204 | 314 | 0.0819 | 10.81 | 4.504 | 0.5328 | 35272.3 | 16700000 | 10300000000 | 7940000000000 | 0.3283 | 0.3071 | 0.0637 | 0.0018 | 0.1924 | 0.0219 | 0.2593 | 0.1299 | 0.1590 | 0.1336 | 0.1409 | 0.1843 | 0.0919 | 0.1786 | 0.0492 | 0.1220 | 0.0306 | 0.1122 | 0.0130 | 0.1156 | 0.0001 | 0.0000 | 0.0004 | 0.0004 | 0.0007 | 0.0005 | 0.0071 | 0.0063 | 0.0513 | 0.0394 | 0.0875 | 0.0698 | 0.0707 | 0.0553 | 0.1096 | 0.0865 | 0.6726 | 0.7417 | 0.0003 | 0.0002 | 0.0010 | 0.0011 | 0.0030 | 0.0057 | 0.0155 | 0.0207 | 0.0717 | 0.0816 | 0.1258 | 0.1367 | 0.0873 | 0.0954 | 0.1313 | 0.1337 | 0.5642 | 0.5249 | 0.0001 | 0.0005 | 0.0021 | 0.0105 | 0.0627 | 0.1064 | 0.0809 | 0.1220 | 0.6149 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 489 | 816 | | 9613 | 19666 | 390.1 | 60.27 | 175.40 | 251.54 | 316 | 341 | 358 | 372 | 386 | 400 | 417 | 439 | 471 | 0.0499 | 981 | 1.140 | 113.53 | 39.96 | 1 | 0.0287 | 276 | 0.0011 | 38.49 | 7.151 | 0.1882 | 155802.0 | 63700000 | 26600000000 | 11400000000000 | 0.4343 | 0.2166 | 0.0001 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0063 | 0.0003 | 0.0283 | 0.0097 | 0.0643 | 0.0203 | 0.0756 | 0.0131 | 0.1055 | 0.0246 | 0.7186 | 0.9320 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0003 | 0.0000 | 0.0028 | 0.0001 | 0.0131 | 0.0084 | 0.0304 | 0.0170 | 0.0306 | 0.0084 | 0.0456 | 0.0152 | 0.8770 | 0.9508 | 0.0087 | 0.0000 | 0.0135 | 0.0000 | 0.0279 | 0.0000 | 0.0983 | 0.0000 | 0.1387 | 0.0000 | 0.1513 | 0.0000 | 0.1416 | 0.0000 | 0.1262 | 0.0000 | 0.2938 | 0.0000 | 0.0011 | 0.0035 | 0.0104 | 0.0298 | 0.0782 | 0.1108 | 0.1017 | 0.1210 | 0.5436 | 14 | 16 | 20 | 33 | 69 | 120 | 189 | 295 | 474 | 0.0394 | 31.15 | 5.368 | 0.5068 | 94034.5 | 84100000 | 103000000000 | 154000000000000 | 0.3897 | 0.2589 | 0.0213 | 0.0011 | 0.1385 | 0.0082 | 0.2420 | 0.0616 | 0.1776 | 0.1065 | 0.1672 | 0.1616 | 0.1236 | 0.1947 | 0.0759 | 0.1312 | 0.0374 | 0.1260 | 0.0167 | 0.2092 | 0.0000 | 0.0000 | 0.0001 | 0.0005 | 0.0018 | 0.0009 | 0.0087 | 0.0075 | 0.0520 | 0.0374 | 0.0873 | 0.0660 | 0.0601 | 0.0490 | 0.0912 | 0.0703 | 0.6988 | 0.7683 | 0.0002 | 0.0002 | 0.0016 | 0.0006 | 0.0035 | 0.0034 | 0.0199 | 0.0226 | 0.0723 | 0.0866 | 0.1159 | 0.1289 | 0.0783 | 0.0860 | 0.1143 | 0.1210 | 0.5940 | 0.5507 | 0.0000 | 0.0008 | 0.0022 | 0.0144 | 0.0633 | 0.0998 | 0.0700 | 0.1025 | 0.6469 |
| MCF7 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 727 | 410 | | 4323 | 18730 | 284.9 | 68.71 | 48.75 | 82.54 | 205 | 226 | 243 | 259 | 275 | 295 | 317 | 340 | 377 | 0.0526 | 985 | 0.713 | 167.73 | 44.42 | 1 | 0.1020 | 441 | 0.0010 | 43.50 | 7.099 | 0.1678 | 85895.4 | 27400000 | 9230000000 | 3280000000000 | 0.4160 | 0.2277 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0066 | 0.0000 | 0.0210 | 0.0018 | 0.0798 | 0.0225 | 0.1736 | 0.0513 | 0.1569 | 0.0548 | 0.1853 | 0.0791 | 0.3760 | 0.7905 | 0.0000 | 0.0000 | 0.0006 | 0.0000 | 0.0029 | 0.0000 | 0.0082 | 0.0009 | 0.0360 | 0.0172 | 0.0703 | 0.0289 | 0.0670 | 0.0280 | 0.0861 | 0.0407 | 0.7289 | 0.8843 | 0.0059 | 0.0118 | 0.0071 | 0.0078 | 0.0142 | 0.0510 | 0.0673 | 0.0980 | 0.1311 | 0.1922 | 0.1865 | 0.1961 | 0.1074 | 0.1059 | 0.1287 | 0.1216 | 0.3518 | 0.2157 | 0.0021 | 0.0010 | 0.0088 | 0.0247 | 0.0809 | 0.1108 | 0.0876 | 0.1221 | 0.5621 | 6 | 8 | 9 | 11 | 13 | 18 | 32 | 65 | 143 | 0.1830 | 2.23 | 3.000 | 0.7083 | 9189.6 | 2810000 | 1040000000 | 430000000000 | 0.5119 | 0.1460 | 0.0261 | 0.0044 | 0.0782 | 0.0114 | 0.1583 | 0.0409 | 0.1676 | 0.0735 | 0.1918 | 0.1395 | 0.1629 | 0.1883 | 0.1006 | 0.1280 | 0.0726 | 0.1513 | 0.0419 | 0.2626 | 0.0010 | 0.0014 | 0.0014 | 0.0020 | 0.0028 | 0.0041 | 0.0130 | 0.0112 | 0.0434 | 0.0338 | 0.0578 | 0.0500 | 0.0580 | 0.0465 | 0.0811 | 0.0695 | 0.7414 | 0.7815 | 0.0000 | 0.0000 | 0.0018 | 0.0028 | 0.0040 | 0.0050 | 0.0143 | 0.0160 | 0.0564 | 0.0607 | 0.0804 | 0.0958 | 0.0666 | 0.0668 | 0.0927 | 0.0914 | 0.6839 | 0.6616 | 0.0000 | 0.0027 | 0.0049 | 0.0151 | 0.0457 | 0.0722 | 0.0624 | 0.0849 | 0.7122 |
| MCF 10A | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1057 | 334 | | 2802 | 7296 | 92.2 | 25.90 | 117.02 | 76.72 | 61 | 72 | 78 | 83 | 89 | 94 | 102 | 114 | 128 | 0.0968 | 706 | 0.875 | 120.79 | 34.99 | 2 | 0.1071 | 300 | 0.0040 | 10.09 | 5.865 | 0.3358 | 9174.8 | 979929 | 112000000 | 13500000000 | 0.4595 | 0.1918 | 0.0026 | 0.0000 | 0.0019 | 0.0000 | 0.0136 | 0.0034 | 0.0285 | 0.0107 | 0.0783 | 0.0390 | 0.1462 | 0.0642 | 0.1481 | 0.0723 | 0.1708 | 0.0985 | 0.4101 | 0.7119 | 0.0005 | 0.0000 | 0.0009 | 0.0000 | 0.0055 | 0.0027 | 0.0110 | 0.0050 | 0.0375 | 0.0249 | 0.0536 | 0.0345 | 0.0659 | 0.0383 | 0.0893 | 0.0509 | 0.7358 | 0.8437 | 0.0031 | 0.0036 | 0.0047 | 0.0182 | 0.0219 | 0.0400 | 0.0470 | 0.0800 | 0.0799 | 0.1091 | 0.1270 | 0.1564 | 0.0831 | 0.1273 | 0.1191 | 0.1309 | 0.5141 | 0.3345 | 0.0057 | 0.0123 | 0.0188 | 0.0286 | 0.0645 | 0.0989 | 0.0784 | 0.1078 | 0.5850 | 35 | 49 | 64 | 82 | 101 | 122 | 146 | 178 | 225 | 0.0071 | 10.21 | 5.520 | 0.4012 | 19579.1 | 4150000 | 1040000000 | 297000000000 | 0.5233 | 0.1494 | 0.0087 | 0.0019 | 0.0570 | 0.0036 | 0.1531 | 0.0185 | 0.1866 | 0.0588 | 0.2102 | 0.1426 | 0.1618 | 0.1929 | 0.1054 | 0.1643 | 0.0688 | 0.1647 | 0.0484 | 0.2527 | 0.0015 | 0.0006 | 0.0028 | 0.0017 | 0.0081 | 0.0062 | 0.0233 | 0.0159 | 0.0535 | 0.0453 | 0.0933 | 0.0805 | 0.0813 | 0.0620 | 0.1102 | 0.0836 | 0.6260 | 0.7042 | 0.0013 | 0.0023 | 0.0047 | 0.0085 | 0.0214 | 0.0194 | 0.0343 | 0.0461 | 0.0909 | 0.1071 | 0.1496 | 0.1720 | 0.1127 | 0.1236 | 0.1444 | 0.1384 | 0.4406 | 0.3827 | 0.0026 | 0.0058 | 0.0125 | 0.0295 | 0.0655 | 0.1210 | 0.1079 | 0.1339 | 0.5213 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 506 | 842 | | 4164 | 7027 | 174.9 | 56.54 | 178.00 | 147.56 | 112 | 130 | 142 | 152 | 163 | 178 | 195 | 217 | 248 | 0.0992 | 697 | 1.133 | 87.73 | 29.97 | 1 | 0.0531 | 221 | 0.0010 | 60.00 | 7.142 | 0.1752 | 33770.8 | 7210000 | 1700000000 | 440000000000 | 0.4464 | 0.2087 | 0.0005 | 0.0000 | 0.0029 | 0.0000 | 0.0141 | 0.0006 | 0.0522 | 0.0044 | 0.1370 | 0.0397 | 0.1936 | 0.0823 | 0.1921 | 0.0887 | 0.1775 | 0.1264 | 0.2301 | 0.6580 | 0.0003 | 0.0000 | 0.0007 | 0.0000 | 0.0030 | 0.0000 | 0.0116 | 0.0021 | 0.0475 | 0.0234 | 0.0857 | 0.0412 | 0.0834 | 0.0368 | 0.1113 | 0.0577 | 0.6565 | 0.8388 | 0.0031 | 0.0022 | 0.0021 | 0.0153 | 0.0073 | 0.0131 | 0.0636 | 0.1160 | 0.1366 | 0.1751 | 0.1783 | 0.2079 | 0.1220 | 0.1072 | 0.1689 | 0.1379 | 0.3180 | 0.2254 | 0.0011 | 0.0006 | 0.0034 | 0.0311 | 0.0911 | 0.1324 | 0.1046 | 0.1414 | 0.4943 | 27 | 50 | 74 | 106 | 140 | 178 | 225 | 292 | 389 | 0.0022 | 67.53 | 7.034 | 0.2591 | 53457.0 | 21400000 | 10400000000 | 5770000000000 | 0.4709 | 0.1839 | 0.0246 | 0.0021 | 0.1054 | 0.0050 | 0.2141 | 0.0504 | 0.1742 | 0.0881 | 0.1708 | 0.1448 | 0.1351 | 0.1725 | 0.0799 | 0.1469 | 0.0654 | 0.1452 | 0.0306 | 0.2451 | 0.0003 | 0.0007 | 0.0014 | 0.0000 | 0.0041 | 0.0026 | 0.0151 | 0.0086 | 0.0704 | 0.0509 | 0.1194 | 0.0961 | 0.0898 | 0.0692 | 0.1292 | 0.1056 | 0.5703 | 0.6664 | 0.0022 | 0.0022 | 0.0035 | 0.0049 | 0.0101 | 0.0121 | 0.0321 | 0.0351 | 0.0981 | 0.1185 | 0.1438 | 0.1580 | 0.1130 | 0.0971 | 0.1328 | 0.1377 | 0.4644 | 0.4344 | 0.0004 | 0.0028 | 0.0042 | 0.0276 | 0.0850 | 0.1324 | 0.0967 | 0.1328 | 0.5181 | ||
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 872 | 892 | | 3689 | 8762 | 488.5 | 108.21 | 84.63 | 135.98 | 344 | 390 | 427 | 458 | 489 | 518 | 545 | 576 | 623 | 0.0781 | 684 | 1.133 | 118.56 | 47.04 | 1 | 0.0848 | 313 | 0.0006 | 83.19 | 7.600 | 0.1213 | 250362.0 | 134000000 | 74800000000 | 43400000000000 | 0.4340 | 0.2055 | 0.0000 | 0.0000 | 0.0004 | 0.0000 | 0.0009 | 0.0003 | 0.0153 | 0.0026 | 0.0610 | 0.0249 | 0.1194 | 0.0435 | 0.1225 | 0.0384 | 0.1500 | 0.0501 | 0.5305 | 0.8402 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0003 | 0.0003 | 0.0075 | 0.0017 | 0.0282 | 0.0215 | 0.0411 | 0.0345 | 0.0380 | 0.0246 | 0.0598 | 0.0328 | 0.8247 | 0.8846 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0231 | 0.0000 | 0.0738 | 0.0000 | 0.1323 | 0.0000 | 0.1877 | 0.0000 | 0.1092 | 0.0000 | 0.1154 | 0.0000 | 0.3569 | 0.0000 | 0.0000 | 0.0011 | 0.0032 | 0.0151 | 0.0572 | 0.1068 | 0.0766 | 0.1176 | 0.6224 | 14 | 16 | 19 | 24 | 34 | 51 | 71 | 100 | 208 | 0.0576 | 11.33 | 4.133 | 0.6484 | 25648.9 | 14400000 | 10400000000 | 8570000000000 | 0.5629 | 0.1030 | 0.0175 | 0.0040 | 0.0903 | 0.0070 | 0.1233 | 0.0663 | 0.1155 | 0.0713 | 0.1291 | 0.1216 | 0.1107 | 0.1266 | 0.1097 | 0.1077 | 0.1175 | 0.1171 | 0.1864 | 0.3784 | 0.0014 | 0.0017 | 0.0025 | 0.0028 | 0.0076 | 0.0083 | 0.0245 | 0.0185 | 0.0736 | 0.0578 | 0.0848 | 0.0797 | 0.0704 | 0.0606 | 0.1050 | 0.0857 | 0.6301 | 0.6850 | 0.0011 | 0.0007 | 0.0011 | 0.0027 | 0.0080 | 0.0066 | 0.0218 | 0.0199 | 0.0856 | 0.0922 | 0.1287 | 0.1293 | 0.0666 | 0.0663 | 0.1034 | 0.1015 | 0.5836 | 0.5809 | 0.0042 | 0.0056 | 0.0075 | 0.0258 | 0.0714 | 0.1104 | 0.0770 | 0.0968 | 0.6012 |
| BT-20 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 465 | 643 | | 8720 | 12380 | 327.7 | 56.71 | 178.47 | 263.33 | 253 | 288 | 306 | 320 | 333 | 346 | 358 | 371 | 394 | 0.0826 | 1023 | 1.053 | 189.34 | 55.01 | 1 | 0.0515 | 449 | 0.0016 | 19.71 | 6.739 | 0.2552 | 110617.0 | 38300000 | 13500000000 | 4860000000000 | 0.4132 | 0.2316 | 0.0001 | 0.0000 | 0.0000 | 0.0001 | 0.0010 | 0.0001 | 0.0059 | 0.0010 | 0.0246 | 0.0101 | 0.0541 | 0.0199 | 0.0557 | 0.0130 | 0.0950 | 0.0226 | 0.7636 | 0.9332 | 0.0000 | 0.0000 | 0.0000 | 0.0001 | 0.0000 | 0.0001 | 0.0030 | 0.0009 | 0.0126 | 0.0096 | 0.0228 | 0.0178 | 0.0228 | 0.0096 | 0.0370 | 0.0162 | 0.9017 | 0.9456 | 0.0114 | 0.0000 | 0.0227 | 0.0000 | 0.0272 | 0.0000 | 0.0681 | 0.0000 | 0.0988 | 0.0000 | 0.1703 | 0.0000 | 0.1067 | 0.0000 | 0.1226 | 0.0000 | 0.3723 | 0.0000 | 0.0008 | 0.0019 | 0.0071 | 0.0173 | 0.0483 | 0.0854 | 0.0861 | 0.1201 | 0.6330 | 18 | 25 | 36 | 52 | 72 | 98 | 148 | 262 | 503 | 0.0250 | 35.86 | 5.284 | 0.5431 | 101188.0 | 92200000 | 104000000000 | 133000000000000 | 0.5504 | 0.1103 | 0.0118 | 0.0028 | 0.0634 | 0.0052 | 0.1160 | 0.0282 | 0.1461 | 0.0612 | 0.1912 | 0.1266 | 0.1751 | 0.1507 | 0.1224 | 0.1351 | 0.0988 | 0.1573 | 0.0752 | 0.3329 | 0.0005 | 0.0002 | 0.0003 | 0.0011 | 0.0024 | 0.0023 | 0.0079 | 0.0094 | 0.0482 | 0.0428 | 0.0854 | 0.0656 | 0.0514 | 0.0563 | 0.0801 | 0.0808 | 0.7238 | 0.7415 | 0.0000 | 0.0000 | 0.0021 | 0.0008 | 0.0042 | 0.0035 | 0.0101 | 0.0097 | 0.0538 | 0.0635 | 0.0894 | 0.0884 | 0.0594 | 0.0666 | 0.0876 | 0.0970 | 0.6934 | 0.6706 | 0.0000 | 0.0003 | 0.0031 | 0.0089 | 0.0520 | 0.0851 | 0.0560 | 0.0875 | 0.7072 |
| MCF7 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1131 | 915 | | 2089 | 9754 | 430.7 | 88.27 | 4.29 | 2.29 | 312 | 347 | 379 | 402 | 426 | 453 | 480 | 511 | 554 | 0.0779 | 760 | 1.256 | 68.26 | 30.41 | 1 | 0.0881 | 184 | 0.0020 | 13.39 | 6.433 | 0.2835 | 193252.0 | 90100000 | 43400000000 | 21600000000000 | 0.4117 | 0.2216 | 0.0000 | 0.0000 | 0.0031 | 0.0000 | 0.0069 | 0.0010 | 0.0138 | 0.0020 | 0.0535 | 0.0221 | 0.0680 | 0.0432 | 0.0688 | 0.0285 | 0.1016 | 0.0569 | 0.6845 | 0.8464 | 0.0000 | 0.0000 | 0.0018 | 0.0000 | 0.0053 | 0.0005 | 0.0065 | 0.0005 | 0.0213 | 0.0187 | 0.0296 | 0.0360 | 0.0260 | 0.0149 | 0.0391 | 0.0316 | 0.8704 | 0.8979 | 0.0000 | 0.0417 | 0.0026 | 0.1042 | 0.0236 | 0.1042 | 0.0289 | 0.1458 | 0.0735 | 0.2083 | 0.0997 | 0.0833 | 0.0919 | 0.1458 | 0.1102 | 0.1250 | 0.5696 | 0.0417 | 0.0020 | 0.0000 | 0.0059 | 0.0129 | 0.0287 | 0.0416 | 0.0505 | 0.0921 | 0.7663 | 2 | 2 | 3 | 3 | 4 | 5 | 5 | 6 | 7 | 0.1846 | 0.51 | 1.036 | 0.4874 | 23.6 | 149.049 | 1043.77 | 7945.36 | 0.5246 | 0.1474 | 0.1109 | 0.0066 | 0.1934 | 0.0403 | 0.2941 | 0.1203 | 0.2455 | 0.1990 | 0.0984 | 0.2637 | 0.0452 | 0.2180 | 0.0124 | 0.1183 | 0.0000 | 0.0305 | 0.0000 | 0.0032 | 0.0060 | 0.0000 | 0.0262 | 0.0025 | 0.0778 | 0.0134 | 0.1544 | 0.0375 | 0.2136 | 0.0942 | 0.2173 | 0.1639 | 0.1817 | 0.2530 | 0.0965 | 0.2739 | 0.0264 | 0.1617 | 0.0166 | 0.0996 | 0.0561 | 0.2292 | 0.1352 | 0.2826 | 0.2123 | 0.2167 | 0.2213 | 0.1091 | 0.1892 | 0.0477 | 0.1151 | 0.0125 | 0.0451 | 0.0027 | 0.0090 | 0.0000 | 0.0060 | 0.0262 | 0.0778 | 0.1544 | 0.2136 | 0.2173 | 0.1817 | 0.0965 | 0.0264 | ||
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 1235 | 928 | | 3908 | 866 | 131.6 | 35.52 | 83.99 | 75.24 | 92 | 104 | 113 | 120 | 128 | 134 | 143 | 154 | 171 | 0.5855 | 507 | 1.261 | 98.62 | 31.32 | 1 | 0.0581 | 227 | 0.0023 | 24.71 | 6.369 | 0.2431 | 18576.3 | 2850000 | 480000000 | 90700000000 | 0.4962 | 0.1800 | 0.0025 | 0.0000 | 0.0025 | 0.0003 | 0.0091 | 0.0020 | 0.0313 | 0.0045 | 0.0844 | 0.0247 | 0.1671 | 0.0656 | 0.1560 | 0.0617 | 0.1844 | 0.1041 | 0.3627 | 0.7372 | 0.0000 | 0.0000 | 0.0013 | 0.0003 | 0.0026 | 0.0016 | 0.0107 | 0.0024 | 0.0488 | 0.0200 | 0.0837 | 0.0431 | 0.0755 | 0.0318 | 0.1153 | 0.0568 | 0.6620 | 0.8442 | 0.0109 | 0.0207 | 0.0125 | 0.0290 | 0.0498 | 0.0290 | 0.0888 | 0.1079 | 0.1495 | 0.1992 | 0.1947 | 0.1826 | 0.1137 | 0.0747 | 0.1340 | 0.1452 | 0.2461 | 0.2116 | 0.0012 | 0.0075 | 0.0184 | 0.0519 | 0.1308 | 0.1360 | 0.1314 | 0.1527 | 0.3700 | 16 | 24 | 36 | 50 | 62 | 79 | 105 | 130 | 176 | 0.0070 | 32.32 | 5.471 | 0.3545 | 12708.8 | 3020000 | 1050000000 | 473000000000 | 0.5943 | 0.0759 | 0.0880 | 0.0099 | 0.2240 | 0.0627 | 0.2160 | 0.0924 | 0.2480 | 0.1881 | 0.1600 | 0.2277 | 0.0560 | 0.2376 | 0.0080 | 0.0792 | 0.0000 | 0.0528 | 0.0000 | 0.0495 | 0.0150 | 0.0019 | 0.0200 | 0.0174 | 0.0324 | 0.0174 | 0.0549 | 0.0581 | 0.2893 | 0.2364 | 0.3566 | 0.3682 | 0.1322 | 0.1492 | 0.0574 | 0.0717 | 0.0424 | 0.0795 | 0.0072 | 0.0047 | 0.0217 | 0.0235 | 0.0580 | 0.0798 | 0.1051 | 0.1221 | 0.2754 | 0.2864 | 0.3370 | 0.3146 | 0.1123 | 0.0986 | 0.0507 | 0.0376 | 0.0326 | 0.0329 | 0.0151 | 0.0151 | 0.0272 | 0.1057 | 0.2779 | 0.3595 | 0.1178 | 0.0453 | 0.0363 | ||
| MCF 10A | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 469 | 396 | | 3985 | 3374 | 160.1 | 46.65 | 190.25 | 141.76 | 107 | 121 | 132 | 142 | 153 | 165 | 177 | 195 | 221 | 0.2110 | 712 | 0.988 | 83.24 | 28.02 | 1 | 0.0575 | 229 | 0.0012 | 50.08 | 6.991 | 0.1783 | 27806.5 | 5240000 | 1070000000 | 235000000000 | 0.4379 | 0.2135 | 0.0010 | 0.0000 | 0.0005 | 0.0000 | 0.0144 | 0.0017 | 0.0460 | 0.0032 | 0.1321 | 0.0326 | 0.1991 | 0.0843 | 0.1709 | 0.0837 | 0.1728 | 0.1160 | 0.2633 | 0.6784 | 0.0007 | 0.0000 | 0.0003 | 0.0000 | 0.0007 | 0.0003 | 0.0098 | 0.0016 | 0.0480 | 0.0199 | 0.0912 | 0.0482 | 0.0784 | 0.0364 | 0.0966 | 0.0566 | 0.6743 | 0.8371 | 0.0069 | 0.0079 | 0.0023 | 0.0237 | 0.0230 | 0.0211 | 0.0746 | 0.0868 | 0.1389 | 0.2237 | 0.1929 | 0.2053 | 0.1114 | 0.0974 | 0.1389 | 0.1316 | 0.3111 | 0.2026 | 0.0017 | 0.0017 | 0.0067 | 0.0274 | 0.1016 | 0.1496 | 0.1111 | 0.1407 | 0.4595 | 58 | 75 | 93 | 117 | 144 | 179 | 227 | 297 | 404 | 0.0022 | 69.15 | 6.693 | 0.2400 | 56286.8 | 22200000 | 10500000000 | 5560000000000 | 0.5618 | 0.1030 | 0.0253 | 0.0040 | 0.1149 | 0.0127 | 0.2821 | 0.0573 | 0.1909 | 0.1131 | 0.1740 | 0.1863 | 0.1166 | 0.2126 | 0.0439 | 0.1242 | 0.0389 | 0.1449 | 0.0135 | 0.1449 | 0.0006 | 0.0019 | 0.0025 | 0.0029 | 0.0125 | 0.0058 | 0.0368 | 0.0277 | 0.1085 | 0.0893 | 0.1696 | 0.1422 | 0.1103 | 0.1053 | 0.1490 | 0.1465 | 0.4102 | 0.4784 | 0.0049 | 0.0037 | 0.0069 | 0.0075 | 0.0208 | 0.0298 | 0.0573 | 0.0658 | 0.1285 | 0.1466 | 0.1887 | 0.1814 | 0.1176 | 0.1379 | 0.1542 | 0.1466 | 0.3211 | 0.2807 | 0.0016 | 0.0071 | 0.0158 | 0.0434 | 0.1278 | 0.1838 | 0.1112 | 0.1546 | 0.3549 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 972 | 177 | | 395 | 12546 | 117.2 | 19.48 | 22.21 | 93.56 | 93 | 98 | 104 | 109 | 113 | 121 | 128 | 137 | 146 | 0.0524 | 657 | 1.105 | 42.05 | 12.04 | 0 | 0.2380 | 94 | 0.0471 | 0.93 | 3.300 | 0.6696 | 14103.0 | 1740000 | 221000000 | 28700000000 | 0.3949 | 0.2407 | 0.0000 | 0.0000 | 0.0102 | 0.0000 | 0.0136 | 0.0000 | 0.0374 | 0.0127 | 0.0646 | 0.0433 | 0.1224 | 0.0738 | 0.1327 | 0.0585 | 0.1565 | 0.0916 | 0.4626 | 0.7201 | 0.0000 | 0.0000 | 0.0028 | 0.0000 | 0.0085 | 0.0000 | 0.0254 | 0.0127 | 0.0366 | 0.0430 | 0.0732 | 0.0734 | 0.0704 | 0.0532 | 0.0789 | 0.0658 | 0.7042 | 0.7519 | 0.0000 | 0.0000 | 0.0164 | 1.0000 | 0.0492 | 0.0000 | 0.0820 | 0.0000 | 0.0984 | 0.0000 | 0.1639 | 0.0000 | 0.1148 | 0.0000 | 0.1967 | 0.0000 | 0.2787 | 0.0000 | 0.0055 | 0.0055 | 0.0000 | 0.0497 | 0.0552 | 0.0718 | 0.0939 | 0.0939 | 0.6243 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 10 | 14 | 0.1205 | 3.55 | 1.534 | 0.4274 | 9246.7 | 8900000 | 10500000000 | 13500000000000 | 0.4645 | 0.1926 | 0.0604 | 0.1758 | 0.1758 | 0.0687 | 0.2582 | 0.0929 | 0.3462 | 0.1414 | 0.1099 | 0.1980 | 0.0385 | 0.1737 | 0.0110 | 0.0747 | 0.0000 | 0.0485 | 0.0000 | 0.0263 | 0.0000 | 0.0672 | 0.0020 | 0.0227 | 0.0099 | 0.0180 | 0.0159 | 0.0164 | 0.0556 | 0.0469 | 0.0724 | 0.0618 | 0.0764 | 0.0641 | 0.1022 | 0.0821 | 0.6657 | 0.6208 | 0.0024 | 0.0000 | 0.0000 | 0.0000 | 0.0024 | 0.0026 | 0.0182 | 0.0140 | 0.0654 | 0.0727 | 0.0956 | 0.0969 | 0.0690 | 0.0625 | 0.0920 | 0.0982 | 0.6550 | 0.6531 | 0.0000 | 0.0022 | 0.0065 | 0.0196 | 0.0577 | 0.0882 | 0.0719 | 0.0882 | 0.6656 |
| MCF7 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 382 | 242 | | 12664 | 34586 | 373.4 | 98.30 | 213.98 | 284.63 | 263 | 291 | 313 | 335 | 358 | 382 | 408 | 446 | 511 | 0.0376 | 1299 | 0.766 | 102.08 | 31.62 | 1 | 0.0237 | 300 | 0.0005 | 74.63 | 7.800 | 0.1485 | 149085.0 | 63700000 | 29200000000 | 14200000000000 | 0.4340 | 0.2186 | 0.0003 | 0.0001 | 0.0035 | 0.0000 | 0.0057 | 0.0011 | 0.0212 | 0.0027 | 0.0752 | 0.0188 | 0.1495 | 0.0375 | 0.1557 | 0.0407 | 0.1833 | 0.0594 | 0.4057 | 0.8397 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0016 | 0.0000 | 0.0071 | 0.0004 | 0.0383 | 0.0102 | 0.0764 | 0.0200 | 0.0727 | 0.0183 | 0.1055 | 0.0299 | 0.6974 | 0.9212 | 0.0052 | 0.0055 | 0.0048 | 0.0036 | 0.0180 | 0.0155 | 0.0557 | 0.0675 | 0.0894 | 0.1150 | 0.1198 | 0.1359 | 0.0802 | 0.1004 | 0.1066 | 0.1305 | 0.5202 | 0.4261 | 0.0011 | 0.0038 | 0.0108 | 0.0345 | 0.0819 | 0.1264 | 0.0936 | 0.1140 | 0.5339 | 10 | 14 | 21 | 42 | 78 | 144 | 249 | 393 | 629 | 0.0536 | 36.30 | 5.670 | 0.4778 | 126798.0 | 105000000 | 105000000000 | 118000000000000 | 0.3874 | 0.2464 | 0.0531 | 0.0011 | 0.1879 | 0.0093 | 0.2767 | 0.0927 | 0.1677 | 0.1537 | 0.1237 | 0.2297 | 0.0869 | 0.1936 | 0.0497 | 0.1194 | 0.0326 | 0.0973 | 0.0216 | 0.1031 | 0.0002 | 0.0002 | 0.0003 | 0.0005 | 0.0015 | 0.0010 | 0.0112 | 0.0071 | 0.0544 | 0.0452 | 0.0794 | 0.0732 | 0.0619 | 0.0524 | 0.0887 | 0.0799 | 0.7024 | 0.7405 | 0.0007 | 0.0001 | 0.0007 | 0.0009 | 0.0015 | 0.0024 | 0.0132 | 0.0185 | 0.0721 | 0.0749 | 0.1034 | 0.1143 | 0.0693 | 0.0766 | 0.1068 | 0.1115 | 0.6324 | 0.6008 | 0.0003 | 0.0004 | 0.0017 | 0.0125 | 0.0632 | 0.0921 | 0.0646 | 0.0980 | 0.6673 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 701 | 317 | | 1010 | 1709 | 117.2 | 14.08 | 14.40 | 13.12 | 99 | 104 | 109 | 112 | 117 | 120 | 125 | 130 | 137 | 0.2264 | 387 | 0.804 | 89.94 | 22.63 | 3 | 0.2515 | 254 | 0.0285 | 1.46 | 3.784 | 0.5971 | 13944.3 | 1680000 | 206000000 | 25500000000 | 0.4094 | 0.2171 | 0.0000 | 0.0000 | 0.0011 | 0.0000 | 0.0032 | 0.0010 | 0.0173 | 0.0079 | 0.0539 | 0.0366 | 0.0949 | 0.0772 | 0.0949 | 0.0475 | 0.1284 | 0.0554 | 0.6063 | 0.7743 | 0.0000 | 0.0000 | 0.0010 | 0.0000 | 0.0031 | 0.0010 | 0.0153 | 0.0079 | 0.0408 | 0.0366 | 0.0704 | 0.0772 | 0.0551 | 0.0475 | 0.0643 | 0.0554 | 0.7500 | 0.7743 | 0.0755 | 0.0000 | 0.0566 | 0.0000 | 0.0755 | 0.0000 | 0.3019 | 0.0000 | 0.1509 | 0.0000 | 0.1698 | 0.0000 | 0.0566 | 0.0000 | 0.0755 | 0.0000 | 0.0377 | 0.0000 | 0.0000 | 0.0119 | 0.0119 | 0.0356 | 0.0652 | 0.1047 | 0.1126 | 0.1285 | 0.5296 | 6 | 7 | 8 | 9 | 10 | 12 | 14 | 18 | 27 | 0.2146 | 0.58 | 2.293 | 0.8004 | 379.5 | 17210.3 | 1060000 | 75400000 | 0.6023 | 0.1002 | 0.1389 | 0.0185 | 0.1528 | 0.0420 | 0.1910 | 0.0791 | 0.2014 | 0.1471 | 0.1632 | 0.1483 | 0.0868 | 0.1508 | 0.0417 | 0.1434 | 0.0243 | 0.1434 | 0.0000 | 0.1273 | 0.0532 | 0.0116 | 0.0388 | 0.0268 | 0.0403 | 0.0528 | 0.0446 | 0.0966 | 0.0935 | 0.1109 | 0.1410 | 0.1270 | 0.0777 | 0.1064 | 0.1410 | 0.1145 | 0.3698 | 0.3533 | 0.0197 | 0.0032 | 0.0221 | 0.0194 | 0.0246 | 0.0227 | 0.0491 | 0.0680 | 0.1302 | 0.1262 | 0.1474 | 0.1780 | 0.1179 | 0.1197 | 0.1843 | 0.1586 | 0.3047 | 0.3042 | 0.0209 | 0.0209 | 0.0342 | 0.0512 | 0.0892 | 0.1518 | 0.0854 | 0.1613 | 0.3852 |
| MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 956 | 595 | | 1268 | 9881 | 91.4 | 16.59 | 53.65 | 107.18 | 71 | 75 | 80 | 84 | 89 | 95 | 101 | 108 | 115 | 0.0764 | 755 | 0.686 | 37.00 | 9.00 | 2 | 0.0694 | 88 | 0.0675 | 0.54 | 2.946 | 0.7664 | 8636.4 | 841834 | 84500000 | 8730000000 | 0.3820 | 0.2594 | 0.0034 | 0.0000 | 0.0101 | 0.0000 | 0.0190 | 0.0000 | 0.0324 | 0.0056 | 0.0738 | 0.0272 | 0.1309 | 0.0769 | 0.1119 | 0.0408 | 0.1644 | 0.0665 | 0.4541 | 0.7830 | 0.0027 | 0.0000 | 0.0063 | 0.0000 | 0.0081 | 0.0000 | 0.0181 | 0.0055 | 0.0433 | 0.0268 | 0.0668 | 0.0702 | 0.0542 | 0.0292 | 0.0713 | 0.0489 | 0.7292 | 0.8194 | 0.0140 | 0.0526 | 0.0047 | 0.0000 | 0.0607 | 0.0526 | 0.0467 | 0.1579 | 0.1215 | 0.4211 | 0.1449 | 0.1053 | 0.1402 | 0.0000 | 0.1869 | 0.1579 | 0.2804 | 0.0526 | 0.0017 | 0.0066 | 0.0150 | 0.0282 | 0.0465 | 0.0781 | 0.0880 | 0.0698 | 0.6661 | 5 | 7 | 8 | 10 | 13 | 24 | 48 | 81 | 142 | 0.0679 | 5.33 | 3.029 | 0.5252 | 14364.0 | 10100000 | 10700000000 | 13000000000000 | 0.4553 | 0.2110 | 0.0320 | 0.0021 | 0.1446 | 0.0121 | 0.2309 | 0.0605 | 0.2156 | 0.1517 | 0.1307 | 0.1944 | 0.1154 | 0.1830 | 0.0654 | 0.1161 | 0.0501 | 0.1061 | 0.0153 | 0.1738 | 0.0000 | 0.0000 | 0.0019 | 0.0003 | 0.0042 | 0.0040 | 0.0160 | 0.0130 | 0.0521 | 0.0454 | 0.0878 | 0.0802 | 0.0597 | 0.0519 | 0.0917 | 0.0918 | 0.6867 | 0.7134 | 0.0012 | 0.0009 | 0.0012 | 0.0019 | 0.0058 | 0.0047 | 0.0162 | 0.0160 | 0.0697 | 0.0782 | 0.1107 | 0.1097 | 0.0680 | 0.0763 | 0.1190 | 0.1266 | 0.6082 | 0.5857 | 0.0000 | 0.0029 | 0.0040 | 0.0169 | 0.0606 | 0.0948 | 0.0671 | 0.1168 | 0.6369 |
| MDA-MB-231 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 354 | 420 | | 1298 | 8819 | 703.5 | 137.06 | 40.06 | 42.60 | 498 | 566 | 622 | 685 | 723 | 762 | 800 | 837 | 868 | 0.0693 | 611 | 0.939 | 34.21 | 8.06 | 4 | 0.0624 | 81 | 0.0013 | 60.83 | 6.801 | 0.1510 | 513652.0 | 387000000 | 299000000000 | 236000000000000 | 0.4003 | 0.2202 | 0.0000 | 0.0000 | 0.0012 | 0.0000 | 0.0012 | 0.0000 | 0.0085 | 0.0008 | 0.0932 | 0.0281 | 0.1538 | 0.0532 | 0.1356 | 0.0258 | 0.1586 | 0.0446 | 0.4479 | 0.8475 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0019 | 0.0008 | 0.0458 | 0.0281 | 0.0715 | 0.0532 | 0.0372 | 0.0258 | 0.0696 | 0.0446 | 0.7741 | 0.8475 | 0.0045 | 0.0000 | 0.0135 | 0.0000 | 0.0269 | 0.0000 | 0.0628 | 0.0000 | 0.1704 | 0.0000 | 0.1883 | 0.0000 | 0.1390 | 0.0000 | 0.1749 | 0.0000 | 0.2197 | 0.0000 | 0.0000 | 0.0000 | 0.0014 | 0.0124 | 0.0634 | 0.1007 | 0.0703 | 0.1131 | 0.6386 | 12 | 14 | 16 | 19 | 24 | 30 | 39 | 56 | 96 | 0.0579 | 5.04 | 3.928 | 0.6486 | 3419.8 | 510086 | 108000000 | 28300000000 | 0.4195 | 0.2154 | 0.0197 | 0.0099 | 0.0599 | 0.0129 | 0.1125 | 0.0254 | 0.1289 | 0.0420 | 0.1724 | 0.0884 | 0.1634 | 0.1256 | 0.1330 | 0.1219 | 0.1371 | 0.1819 | 0.0731 | 0.3921 | 0.0057 | 0.0056 | 0.0106 | 0.0065 | 0.0157 | 0.0127 | 0.0205 | 0.0169 | 0.0410 | 0.0340 | 0.0651 | 0.0498 | 0.0576 | 0.0514 | 0.0923 | 0.0910 | 0.6916 | 0.7322 | 0.0014 | 0.0017 | 0.0062 | 0.0028 | 0.0105 | 0.0062 | 0.0253 | 0.0258 | 0.0581 | 0.0624 | 0.0781 | 0.0983 | 0.0696 | 0.0736 | 0.0948 | 0.0893 | 0.6560 | 0.6399 | 0.0019 | 0.0054 | 0.0101 | 0.0260 | 0.0490 | 0.0707 | 0.0634 | 0.1014 | 0.6720 |
| MDA-MB-231 | Barasertib | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 16 | 1 | 170 | 550 | | 8750 | 8424 | 502.4 | 87.96 | 41.36 | 73.23 | 382 | 421 | 449 | 477 | 504 | 533 | 561 | 587 | 616 | 0.0991 | 835 | 0.776 | 84.48 | 24.52 | 5 | 0.0277 | 242 | 0.0010 | 31.96 | 7.187 | 0.2170 | 260103.0 | 138000000 | 75400000000 | 41900000000000 | 0.4172 | 0.2234 | 0.0005 | 0.0000 | 0.0021 | 0.0000 | 0.0032 | 0.0000 | 0.0111 | 0.0005 | 0.0476 | 0.0114 | 0.0760 | 0.0187 | 0.0904 | 0.0131 | 0.1317 | 0.0244 | 0.6373 | 0.9319 | 0.0003 | 0.0000 | 0.0001 | 0.0000 | 0.0008 | 0.0000 | 0.0043 | 0.0005 | 0.0214 | 0.0113 | 0.0331 | 0.0183 | 0.0365 | 0.0119 | 0.0525 | 0.0214 | 0.8509 | 0.9367 | 0.0126 | 0.1000 | 0.0126 | 0.2000 | 0.0356 | 0.5000 | 0.0617 | 0.2000 | 0.1146 | 0.0000 | 0.1486 | 0.0000 | 0.1328 | 0.0000 | 0.1518 | 0.0000 | 0.3296 | 0.0000 | 0.0014 | 0.0023 | 0.0063 | 0.0160 | 0.0405 | 0.0657 | 0.0673 | 0.0822 | 0.7184 | 8 | 10 | 12 | 13 | 16 | 20 | 28 | 44 | 98 | 0.1584 | 2.61 | 3.052 | 0.7597 | 7073.0 | 2420000 | 1080000000 | 547000000000 | 0.6438 | 0.0750 | 0.0266 | 0.0119 | 0.0620 | 0.0252 | 0.1004 | 0.0365 | 0.1492 | 0.0697 | 0.1905 | 0.1048 | 0.1418 | 0.1287 | 0.1536 | 0.1301 | 0.0960 | 0.1858 | 0.0798 | 0.3072 | 0.0055 | 0.0063 | 0.0104 | 0.0116 | 0.0127 | 0.0137 | 0.0209 | 0.0256 | 0.0563 | 0.0460 | 0.0700 | 0.0674 | 0.0691 | 0.0593 | 0.1004 | 0.1092 | 0.6547 | 0.6608 | 0.0000 | 0.0045 | 0.0052 | 0.0037 | 0.0085 | 0.0082 | 0.0184 | 0.0231 | 0.0636 | 0.0723 | 0.0932 | 0.0835 | 0.0636 | 0.0776 | 0.1122 | 0.1148 | 0.6352 | 0.6122 | 0.0011 | 0.0038 | 0.0098 | 0.0235 | 0.0573 | 0.0742 | 0.0770 | 0.1070 | 0.6463 |
| MCF 10A | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 463 | 730 | | 6826 | 14133 | 120.4 | 23.00 | 116.76 | 79.84 | 93 | 102 | 108 | 113 | 119 | 124 | 130 | 137 | 150 | 0.0723 | 1022 | 1.085 | 103.16 | 28.18 | 1 | 0.0349 | 238 | 0.0037 | 11.96 | 5.947 | 0.3160 | 15021.5 | 1940000 | 260000000 | 36200000000 | 0.4335 | 0.2237 | 0.0000 | 0.0000 | 0.0012 | 0.0002 | 0.0044 | 0.0009 | 0.0154 | 0.0017 | 0.0519 | 0.0164 | 0.0996 | 0.0314 | 0.1171 | 0.0321 | 0.1581 | 0.0575 | 0.5524 | 0.8598 | 0.0000 | 0.0000 | 0.0003 | 0.0000 | 0.0008 | 0.0003 | 0.0060 | 0.0004 | 0.0250 | 0.0105 | 0.0473 | 0.0218 | 0.0483 | 0.0136 | 0.0723 | 0.0276 | 0.7998 | 0.9258 | 0.0111 | 0.0195 | 0.0101 | 0.0469 | 0.0364 | 0.0703 | 0.1083 | 0.1367 | 0.1447 | 0.1680 | 0.1903 | 0.1992 | 0.1326 | 0.0977 | 0.1164 | 0.1094 | 0.2500 | 0.1523 | 0.0021 | 0.0061 | 0.0177 | 0.0360 | 0.0903 | 0.1196 | 0.1114 | 0.1422 | 0.4745 | 27 | 44 | 61 | 81 | 101 | 124 | 151 | 182 | 227 | 0.0032 | 25.81 | 6.449 | 0.3268 | 20005.6 | 4300000 | 1080000000 | 305000000000 | 0.5926 | 0.1078 | 0.0158 | 0.0022 | 0.1055 | 0.0083 | 0.2116 | 0.0336 | 0.1858 | 0.0797 | 0.1786 | 0.1495 | 0.1481 | 0.2016 | 0.0911 | 0.1603 | 0.0466 | 0.1718 | 0.0169 | 0.1931 | 0.0011 | 0.0005 | 0.0019 | 0.0017 | 0.0046 | 0.0033 | 0.0183 | 0.0093 | 0.0620 | 0.0454 | 0.1196 | 0.0892 | 0.1019 | 0.0765 | 0.1366 | 0.1110 | 0.5541 | 0.6630 | 0.0017 | 0.0050 | 0.0065 | 0.0107 | 0.0178 | 0.0259 | 0.0421 | 0.0517 | 0.1004 | 0.1214 | 0.1658 | 0.1753 | 0.1211 | 0.1343 | 0.1429 | 0.1473 | 0.4017 | 0.3284 | 0.0007 | 0.0028 | 0.0097 | 0.0328 | 0.0821 | 0.1460 | 0.1176 | 0.1387 | 0.4696 |