High-content imaging of six breast cancer cell lines treated with a library of small molecule kinase inhibitors. - Dataset (ID:20244)
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Cell | SM Name | Small Mol Concentration | Small Mol Conc Unit | Other Reagent 1 Name | Other Reagent 1 Detection Channel | Other Reagent 2 Name | Other Reagent 2 Detection Channel | Row | Column | Field | X-coordinate | Y-coordinate | Image | Nuclear area (pixels) | Cytoplasm area (pixels) | Nuclear intensity (AU) | Std Dev of nuclear intensity (AU) | Cytoplasm intensity (AU) | Std Dev of cytoplasm intensity (AU) | 10% quantile of nuclear intensity (AU) | 20% quantile of nuclear intensity (AU) | 30% quantile of nuclear intensity (AU) | 40% quantile of nuclear intensity (AU) | 50% quantile of nuclear intensity (AU) | 60% quantile of nuclear intensity (AU) | 70% quantile of nuclear intensity (AU) | 80% quantile of nuclear intensity (AU) | 90% quantile of nuclear intensity (AU) | Ratio of cytoplasm perimeter to area | Cytoplasm perimeter (pixels) | Nuclear roundness | Nuclear length (pixels) | Nuclear halfwidth (pixels) | Number of nuclei | Ratio of nuclear perimeter to area | Nuclear perimeter (pixels) | Nuclear Haralick ASM | Nuclear Haralick contrast | Nuclear Haralick entropy | Nuclear Haralick IDM | Nuclear Haralick moment 2 | Nuclear Haralick moment 3 | Nuclear Haralick moment 4 | Nuclear Haralick moment 5 | Nuclear radial moment (border) | Nuclear radial moment (center) | Nuclear Threshold Adj Stat 1 (Threshold: 0.2) | Nuclear Threshold Adj Stat 1 (Threshold: 0.4) | Nuclear Threshold Adj Stat 2 (Threshold: 0.2) | Nuclear Threshold Adj Stat 2 (Threshold: 0.4) | Nuclear Threshold Adj Stat 3 (Threshold: 0.2) | Nuclear Threshold Adj Stat 3 (Threshold: 0.4) | Nuclear Threshold Adj Stat 4 (Threshold: 0.2) | Nuclear Threshold Adj Stat 4 (Threshold: 0.4) | Nuclear Threshold Adj Stat 5 (Threshold: 0.2) | Nuclear Threshold Adj Stat 5 (Threshold: 0.4) | Nuclear Threshold Adj Stat 6 (Threshold: 0.2) | Nuclear Threshold Adj Stat 6 (Threshold: 0.4) | Nuclear Threshold Adj Stat 7 (Threshold: 0.2) | Nuclear Threshold Adj Stat 7 (Threshold: 0.4) | Nuclear Threshold Adj Stat 8 (Threshold: 0.2) | Nuclear Threshold Adj Stat 8 (Threshold: 0.4) | Nuclear Threshold Adj Stat 9 (Threshold: 0.2) | Nuclear Threshold Adj Stat 9 (Threshold: 0.4) | Nuclear Threshold Adj Stat 10 (Threshold: 0.2) | Nuclear Threshold Adj Stat 10 (Threshold: 0.4) | Nuclear Threshold Adj Stat 11 (Threshold: 0.2) | Nuclear Threshold Adj Stat 11 (Threshold: 0.4) | Nuclear Threshold Adj Stat 12 (Threshold: 0.2) | Nuclear Threshold Adj Stat 12 (Threshold: 0.4) | Nuclear Threshold Adj Stat 13 (Threshold: 0.2) | Nuclear Threshold Adj Stat 13 (Threshold: 0.4) | Nuclear Threshold Adj Stat 14 (Threshold: 0.2) | Nuclear Threshold Adj Stat 14 (Threshold: 0.4) | Nuclear Threshold Adj Stat 15 (Threshold: 0.2) | Nuclear Threshold Adj Stat 15 (Threshold: 0.4) | Nuclear Threshold Adj Stat 16 (Threshold: 0.2) | Nuclear Threshold Adj Stat 16 (Threshold: 0.4) | Nuclear Threshold Adj Stat 17 (Threshold: 0.2) | Nuclear Threshold Adj Stat 17 (Threshold: 0.4) | Nuclear Threshold Adj Stat 18 (Threshold: 0.2) | Nuclear Threshold Adj Stat 18 (Threshold: 0.4) | Nuclear Threshold Adj Stat 19 (Threshold: 0.2) | Nuclear Threshold Adj Stat 19 (Threshold: 0.4) | Nuclear Threshold Adj Stat 20 (Threshold: 0.2) | Nuclear Threshold Adj Stat 20 (Threshold: 0.4) | Nuclear Threshold Adj Stat 21 (Threshold: 0.2) | Nuclear Threshold Adj Stat 21 (Threshold: 0.4) | Nuclear Threshold Adj Stat 22 (Threshold: 0.2) | Nuclear Threshold Adj Stat 22 (Threshold: 0.4) | Nuclear Threshold Adj Stat 23 (Threshold: 0.2) | Nuclear Threshold Adj Stat 23 (Threshold: 0.4) | Nuclear Threshold Adj Stat 24 (Threshold: 0.2) | Nuclear Threshold Adj Stat 24 (Threshold: 0.4) | Nuclear Threshold Adj Stat 25 (Threshold: 0.2) | Nuclear Threshold Adj Stat 25 (Threshold: 0.4) | Nuclear Threshold Adj Stat 26 (Threshold: 0.2) | Nuclear Threshold Adj Stat 26 (Threshold: 0.4) | Nuclear Threshold Adj Stat 27 (Threshold: 0.2) | Nuclear Threshold Adj Stat 27 (Threshold: 0.4) | Nuclear Threshold Adj Stat 28 | Nuclear Threshold Adj Stat 29 | Nuclear Threshold Adj Stat 30 | Nuclear Threshold Adj Stat 31 | Nuclear Threshold Adj Stat 32 | Nuclear Threshold Adj Stat 33 | Nuclear Threshold Adj Stat 34 | Nuclear Threshold Adj Stat 35 | Nuclear Threshold Adj Stat 36 | 10% quantile of cytoplasm intensity (AU) | 20% quantile of cytoplasm intensity (AU) | 30% quantile of cytoplasm intensity (AU) | 40% quantile of cytoplasm intensity (AU) | 50% quantile of cytoplasm intensity (AU) | 60% quantile of cytoplasm intensity (AU) | 70% quantile of cytoplasm intensity (AU) | 80% quantile of cytoplasm intensity (AU) | 90% quantile of cytoplasm intensity (AU) | Cytoplasmic Haralick ASM | Cytoplasmic Haralick contrast | Cytoplasmic Haralick entropy | Cytoplasmic Haralick IDM | Cytoplasmic Haralick moment 2 | Cytoplasmic Haralick moment 3 | Cytoplasmic Haralick moment 4 | Cytoplasmic Haralick moment 5 | Cytoplasmic radial moment (border) | Cytoplasmic radial moment (center) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 1 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 2 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 3 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 4 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 5 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 6 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 7 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 8 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 9 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 10 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 11 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 12 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 13 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 14 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 15 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 16 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 17 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 18 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 19 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 20 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 21 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 22 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 23 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 24 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 25 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 26 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.2) | Cytoplasmic Threshold Adj Stat 27 (Threshold: 0.4) | Cytoplasmic Threshold Adj Stat 28 | Cytoplasmic Threshold Adj Stat 29 | Cytoplasmic Threshold Adj Stat 30 | Cytoplasmic Threshold Adj Stat 31 | Cytoplasmic Threshold Adj Stat 32 | Cytoplasmic Threshold Adj Stat 33 | Cytoplasmic Threshold Adj Stat 34 | Cytoplasmic Threshold Adj Stat 35 | Cytoplasmic Threshold Adj Stat 36 |
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Hs 578T | A443654 | 1.1 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 12 | 1 | 992 | 554 | 458 | 453 | 58.6 | 18.24 | 15.98 | 3.18 | 38 | 42 | 46 | 52 | 56 | 61 | 66 | 72 | 84 | 0.4040 | 183 | 0.735 | 110.07 | 27.07 | 1 | 0.6135 | 281 | 0.0119 | 5.25 | 4.713 | 0.4351 | 3769.0 | 265175 | 20300000 | 1680000000 | 0.3546 | 0.2594 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0448 | 0.0000 | 0.0597 | 0.0052 | 0.1294 | 0.0735 | 0.2139 | 0.1417 | 0.1791 | 0.0761 | 0.1343 | 0.1155 | 0.2189 | 0.5879 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0164 | 0.0046 | 0.0656 | 0.0371 | 0.1049 | 0.0928 | 0.0721 | 0.0278 | 0.0951 | 0.0603 | 0.6459 | 0.7773 | 0.0096 | 0.0000 | 0.0000 | 0.0000 | 0.0096 | 0.0600 | 0.0673 | 0.1800 | 0.2019 | 0.1000 | 0.1731 | 0.2800 | 0.0865 | 0.1400 | 0.1635 | 0.0600 | 0.2885 | 0.1800 | 0.0000 | 0.0000 | 0.0048 | 0.0335 | 0.1435 | 0.1483 | 0.1100 | 0.1627 | 0.3971 | 12 | 13 | 14 | 15 | 16 | 17 | 17 | 18 | 20 | 0.8738 | 0.06 | 0.306 | 0.9702 | 265.5 | 4574.87 | 81636.7 | 1510000 | 0.5349 | 0.1049 | 0.0031 | 0.0000 | 0.0217 | 0.0000 | 0.0683 | 0.0046 | 0.1211 | 0.0207 | 0.2050 | 0.1359 | 0.1739 | 0.1544 | 0.1739 | 0.1613 | 0.1801 | 0.1521 | 0.0528 | 0.3710 | 0.0026 | 0.0000 | 0.0078 | 0.0000 | 0.0284 | 0.0045 | 0.0413 | 0.0089 | 0.1835 | 0.1250 | 0.1550 | 0.1473 | 0.1576 | 0.1518 | 0.1938 | 0.1384 | 0.2300 | 0.4241 | 0.2923 | 0.5000 | 0.1846 | 0.2143 | 0.1385 | 0.2143 | 0.1846 | 0.0714 | 0.1077 | 0.0000 | 0.0615 | 0.0000 | 0.0308 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0195 | 0.0586 | 0.1328 | 0.1445 | 0.1758 | 0.1680 | 0.1367 | 0.1055 | 0.0586 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 897 | 352 | 491 | 10165 | 31.2 | 10.66 | 5.57 | 2.04 | 21 | 23 | 24 | 26 | 27 | 30 | 34 | 40 | 49 | 0.0858 | 872 | 0.813 | 87.21 | 20.59 | 5 | 0.4073 | 200 | 0.0618 | 0.76 | 3.150 | 0.6872 | 1083.9 | 42132.6 | 1810000 | 83600000 | 0.3481 | 0.2731 | 0.0093 | 0.0000 | 0.0093 | 0.0000 | 0.0187 | 0.0025 | 0.0561 | 0.0150 | 0.1168 | 0.0848 | 0.2336 | 0.0798 | 0.1963 | 0.0873 | 0.1869 | 0.1446 | 0.1729 | 0.5860 | 0.0061 | 0.0000 | 0.0061 | 0.0000 | 0.0122 | 0.0021 | 0.0334 | 0.0125 | 0.0608 | 0.0582 | 0.0912 | 0.0353 | 0.0821 | 0.0561 | 0.1003 | 0.0811 | 0.6079 | 0.7547 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0348 | 0.0625 | 0.0609 | 0.0500 | 0.1391 | 0.1625 | 0.0609 | 0.1125 | 0.1043 | 0.0750 | 0.6000 | 0.5375 | 0.0000 | 0.0107 | 0.0000 | 0.0481 | 0.0428 | 0.1070 | 0.0695 | 0.1016 | 0.6203 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.0061 | 0.11 | 0.381 | 0.0699 | 35.2 | 247.481 | 1925.98 | 16644.2 | 0.5163 | 0.1494 | 0.0075 | 0.0004 | 0.0317 | 0.0014 | 0.1096 | 0.0083 | 0.1889 | 0.0233 | 0.2557 | 0.0515 | 0.2310 | 0.1180 | 0.1247 | 0.2326 | 0.0447 | 0.3477 | 0.0060 | 0.2168 | 0.0016 | 0.0000 | 0.0075 | 0.0002 | 0.0348 | 0.0045 | 0.0908 | 0.0154 | 0.1571 | 0.0325 | 0.2323 | 0.0692 | 0.2275 | 0.1499 | 0.1597 | 0.3269 | 0.0887 | 0.4014 | 0.2469 | 0.4372 | 0.2984 | 0.2271 | 0.1850 | 0.0804 | 0.0888 | 0.0635 | 0.0564 | 0.0536 | 0.0355 | 0.0409 | 0.0392 | 0.0381 | 0.0282 | 0.0381 | 0.0214 | 0.0212 | 0.0197 | 0.0760 | 0.1532 | 0.2101 | 0.1844 | 0.1602 | 0.1001 | 0.0600 | 0.0363 | |
SK-BR-3 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 705 | 656 | 2086 | 7084 | 755.3 | 409.67 | 4.68 | 2.47 | 169 | 264 | 426 | 649 | 862 | 982 | 1060 | 1141 | 1240 | 0.0841 | 596 | 0.902 | 85.38 | 22.85 | 2 | 0.1112 | 232 | 0.0008 | 88.53 | 7.287 | 0.1150 | 738249.0 | 798000000 | 907000000000 | 1.07E+15 | 0.3090 | 0.2823 | 0.0000 | 0.0000 | 0.0167 | 0.0013 | 0.0167 | 0.0013 | 0.0733 | 0.0088 | 0.3067 | 0.1107 | 0.2867 | 0.1723 | 0.1300 | 0.1233 | 0.1300 | 0.1849 | 0.0400 | 0.3975 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0016 | 0.0000 | 0.0264 | 0.0280 | 0.0380 | 0.0350 | 0.0233 | 0.0224 | 0.0396 | 0.0378 | 0.8712 | 0.8768 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0010 | 0.0016 | 0.0030 | 0.0174 | 0.0324 | 0.0757 | 0.0576 | 0.1372 | 0.0536 | 0.0931 | 0.0890 | 0.1483 | 0.7634 | 0.5268 | 0.0000 | 0.0000 | 0.0000 | 0.0009 | 0.0328 | 0.0345 | 0.0276 | 0.0405 | 0.8638 | 2 | 3 | 3 | 4 | 4 | 5 | 6 | 7 | 8 | 0.0353 | 0.22 | 0.723 | 0.2177 | 28.0 | 197.373 | 1573.42 | 13861.8 | 0.4480 | 0.1854 | 0.0919 | 0.0083 | 0.1989 | 0.0206 | 0.2527 | 0.0511 | 0.2301 | 0.0975 | 0.1382 | 0.1832 | 0.0656 | 0.2464 | 0.0204 | 0.2343 | 0.0022 | 0.1254 | 0.0000 | 0.0331 | 0.0082 | 0.0009 | 0.0316 | 0.0026 | 0.0687 | 0.0139 | 0.0919 | 0.0357 | 0.1178 | 0.0764 | 0.1357 | 0.1283 | 0.1428 | 0.1664 | 0.1753 | 0.2158 | 0.2280 | 0.3601 | 0.0631 | 0.0852 | 0.0954 | 0.1085 | 0.0927 | 0.1085 | 0.0907 | 0.1143 | 0.1286 | 0.1214 | 0.1226 | 0.1375 | 0.1302 | 0.1336 | 0.1434 | 0.0943 | 0.1334 | 0.0968 | 0.0278 | 0.0633 | 0.1001 | 0.0986 | 0.1143 | 0.1134 | 0.1331 | 0.1597 | 0.1898 | |||
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 1275 | 136 | 348 | 1761 | 24.9 | 4.56 | 12.04 | 4.73 | 19 | 21 | 22 | 24 | 25 | 26 | 27 | 29 | 31 | 0.1550 | 273 | 0.753 | 89.14 | 19.31 | 1 | 0.6466 | 225 | 0.0917 | 1.19 | 2.649 | 0.6279 | 641.9 | 17045.4 | 465908 | 13100000 | 0.3990 | 0.2249 | 0.0000 | 0.0000 | 0.0040 | 0.0000 | 0.0283 | 0.0000 | 0.0850 | 0.0208 | 0.1377 | 0.0564 | 0.1903 | 0.0682 | 0.2510 | 0.0653 | 0.1984 | 0.1721 | 0.1053 | 0.6172 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0097 | 0.0000 | 0.0355 | 0.0145 | 0.0548 | 0.0609 | 0.0613 | 0.0522 | 0.0968 | 0.0551 | 0.2194 | 0.0725 | 0.5226 | 0.7449 | 0.0476 | 0.6250 | 0.1746 | 0.2500 | 0.1270 | 0.1250 | 0.2857 | 0.0000 | 0.1746 | 0.0000 | 0.1111 | 0.0000 | 0.0794 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0056 | 0.0278 | 0.0778 | 0.0889 | 0.1611 | 0.2111 | 0.2000 | 0.1722 | 0.0556 | 7 | 7 | 9 | 11 | 11 | 13 | 14 | 16 | 18 | 0.4459 | 0.26 | 0.850 | 0.7731 | 167.2 | 2583.98 | 43505.2 | 785905 | 0.4996 | 0.1549 | 0.0715 | 0.0083 | 0.1464 | 0.0379 | 0.2230 | 0.0592 | 0.2379 | 0.0981 | 0.1747 | 0.1637 | 0.0948 | 0.2202 | 0.0349 | 0.2239 | 0.0166 | 0.1508 | 0.0000 | 0.0379 | 0.0196 | 0.0065 | 0.0267 | 0.0196 | 0.0364 | 0.0224 | 0.0756 | 0.0427 | 0.0907 | 0.0782 | 0.1307 | 0.0941 | 0.1627 | 0.1260 | 0.1956 | 0.2288 | 0.2622 | 0.3816 | 0.0611 | 0.1433 | 0.0630 | 0.1533 | 0.1183 | 0.2067 | 0.1756 | 0.1600 | 0.1584 | 0.1267 | 0.1737 | 0.1000 | 0.1317 | 0.0667 | 0.0954 | 0.0333 | 0.0229 | 0.0100 | 0.0427 | 0.0380 | 0.0617 | 0.1032 | 0.1329 | 0.1696 | 0.1459 | 0.1969 | 0.1091 | |
SK-BR-3 | A443654 | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 11 | 1 | 502 | 891 | 697 | 2813 | 320.4 | 207.81 | 13.17 | 5.09 | 98 | 125 | 170 | 212 | 264 | 326 | 402 | 514 | 669 | 0.1337 | 376 | 1.160 | 26.25 | 8.00 | 2 | 0.0918 | 64 | 0.0019 | 99.20 | 6.369 | 0.1311 | 145754.0 | 81100000 | 50300000000 | 33200000000000 | 0.2968 | 0.3295 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0303 | 0.0000 | 0.0909 | 0.0036 | 0.2348 | 0.1155 | 0.2348 | 0.1769 | 0.2273 | 0.1227 | 0.1288 | 0.1444 | 0.0530 | 0.4368 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0084 | 0.0022 | 0.0503 | 0.0508 | 0.0670 | 0.0640 | 0.0475 | 0.0375 | 0.0587 | 0.0486 | 0.7682 | 0.7969 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0133 | 0.0114 | 0.0487 | 0.0739 | 0.1062 | 0.0966 | 0.0442 | 0.0568 | 0.0752 | 0.0852 | 0.7124 | 0.6761 | 0.0000 | 0.0000 | 0.0000 | 0.0035 | 0.0565 | 0.0919 | 0.0389 | 0.0671 | 0.7420 | 7 | 9 | 10 | 12 | 13 | 14 | 15 | 17 | 20 | 0.4201 | 0.26 | 1.281 | 0.8672 | 199.4 | 3414.53 | 65866.6 | 1430000 | 0.5670 | 0.1264 | 0.0375 | 0.0039 | 0.0586 | 0.0218 | 0.0980 | 0.0262 | 0.1548 | 0.0510 | 0.1951 | 0.0694 | 0.2070 | 0.0879 | 0.1712 | 0.1422 | 0.0678 | 0.2146 | 0.0101 | 0.3830 | 0.0136 | 0.0020 | 0.0172 | 0.0131 | 0.0183 | 0.0127 | 0.0365 | 0.0295 | 0.0662 | 0.0516 | 0.0986 | 0.0540 | 0.1377 | 0.0704 | 0.2165 | 0.1101 | 0.3954 | 0.6566 | 0.0545 | 0.0966 | 0.0703 | 0.0914 | 0.0812 | 0.0914 | 0.1018 | 0.1227 | 0.1115 | 0.1488 | 0.1236 | 0.1488 | 0.1164 | 0.1175 | 0.1794 | 0.1071 | 0.1612 | 0.0757 | 0.0122 | 0.0278 | 0.0523 | 0.0733 | 0.1025 | 0.1263 | 0.1514 | 0.1826 | 0.2716 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 613 | 713 | 713 | 1229 | 91.3 | 14.01 | 6.39 | 2.54 | 72 | 77 | 83 | 87 | 92 | 96 | 100 | 104 | 109 | 0.2522 | 310 | 1.070 | 24.52 | 7.28 | 1 | 0.0884 | 63 | 0.0680 | 0.69 | 2.897 | 0.7227 | 8522.9 | 813628 | 79300000 | 7870000000 | 0.3848 | 0.2534 | 0.0000 | 0.0000 | 0.0053 | 0.0000 | 0.0123 | 0.0014 | 0.0247 | 0.0014 | 0.0670 | 0.0492 | 0.0917 | 0.0646 | 0.1217 | 0.0478 | 0.1711 | 0.0772 | 0.5062 | 0.7584 | 0.0000 | 0.0000 | 0.0048 | 0.0000 | 0.0095 | 0.0014 | 0.0127 | 0.0014 | 0.0523 | 0.0491 | 0.0507 | 0.0645 | 0.0555 | 0.0477 | 0.0777 | 0.0659 | 0.7369 | 0.7700 | 0.0156 | 1.0000 | 0.0938 | 0.0000 | 0.0625 | 0.0000 | 0.1406 | 0.0000 | 0.2344 | 0.0000 | 0.1875 | 0.0000 | 0.0781 | 0.0000 | 0.1094 | 0.0000 | 0.0781 | 0.0000 | 0.0053 | 0.0107 | 0.0213 | 0.0373 | 0.0613 | 0.0587 | 0.0827 | 0.1280 | 0.5947 | 3 | 5 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 0.0448 | 0.26 | 0.778 | 0.2347 | 47.3 | 411.762 | 4361.59 | 56996.9 | 0.5177 | 0.1432 | 0.0094 | 0.0021 | 0.0336 | 0.0064 | 0.0983 | 0.0364 | 0.1023 | 0.0621 | 0.1911 | 0.1424 | 0.2248 | 0.1681 | 0.1736 | 0.2141 | 0.1279 | 0.2473 | 0.0390 | 0.1210 | 0.0000 | 0.0000 | 0.0048 | 0.0009 | 0.0183 | 0.0109 | 0.0502 | 0.0263 | 0.1187 | 0.1069 | 0.1525 | 0.1295 | 0.2008 | 0.1639 | 0.2346 | 0.2473 | 0.2201 | 0.3143 | 0.1365 | 0.2588 | 0.2048 | 0.1882 | 0.1468 | 0.1353 | 0.1433 | 0.1353 | 0.1502 | 0.0588 | 0.0785 | 0.0471 | 0.0512 | 0.0529 | 0.0375 | 0.0412 | 0.0512 | 0.0824 | 0.0038 | 0.0368 | 0.0722 | 0.1293 | 0.1812 | 0.1787 | 0.1496 | 0.1546 | 0.0938 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 424 | 598 | 10118 | 27401 | 44.6 | 15.32 | 9.66 | 10.14 | 26 | 30 | 34 | 39 | 43 | 46 | 51 | 58 | 68 | 0.0697 | 1910 | 0.653 | 52.00 | 10.05 | 2 | 0.0153 | 155 | 0.0320 | 0.80 | 3.734 | 0.7116 | 2220.7 | 121956 | 7260000 | 460000000 | 0.4370 | 0.1928 | 0.0033 | 0.0009 | 0.0117 | 0.0021 | 0.0212 | 0.0062 | 0.0405 | 0.0162 | 0.0660 | 0.0337 | 0.0944 | 0.0462 | 0.1215 | 0.0617 | 0.1775 | 0.0854 | 0.4639 | 0.7475 | 0.0012 | 0.0004 | 0.0041 | 0.0011 | 0.0082 | 0.0029 | 0.0150 | 0.0080 | 0.0223 | 0.0197 | 0.0297 | 0.0256 | 0.0429 | 0.0335 | 0.0634 | 0.0478 | 0.8132 | 0.8611 | 0.0054 | 0.0041 | 0.0122 | 0.0117 | 0.0168 | 0.0233 | 0.0337 | 0.0425 | 0.0471 | 0.0487 | 0.0631 | 0.0720 | 0.0608 | 0.0822 | 0.0838 | 0.0864 | 0.6771 | 0.6292 | 0.0039 | 0.0100 | 0.0142 | 0.0234 | 0.0345 | 0.0395 | 0.0542 | 0.0860 | 0.7342 | 4 | 5 | 6 | 7 | 7 | 8 | 9 | 11 | 16 | 0.0607 | 0.27 | 1.084 | 0.3393 | 196.2 | 10715.8 | 1130000 | 163000000 | 0.5653 | 0.1216 | 0.0777 | 0.0043 | 0.1202 | 0.0147 | 0.1403 | 0.0416 | 0.1602 | 0.0819 | 0.1662 | 0.1200 | 0.1599 | 0.1529 | 0.1160 | 0.1781 | 0.0486 | 0.2087 | 0.0109 | 0.1979 | 0.0433 | 0.0019 | 0.0675 | 0.0095 | 0.0728 | 0.0304 | 0.0744 | 0.0626 | 0.0830 | 0.0967 | 0.0877 | 0.1232 | 0.0996 | 0.1307 | 0.1151 | 0.1503 | 0.3566 | 0.3946 | 0.0629 | 0.0327 | 0.0480 | 0.0262 | 0.0487 | 0.0276 | 0.0411 | 0.0316 | 0.0533 | 0.0584 | 0.0696 | 0.0784 | 0.0791 | 0.0835 | 0.1064 | 0.1232 | 0.4909 | 0.5384 | 0.0684 | 0.0635 | 0.0650 | 0.0662 | 0.0726 | 0.0769 | 0.0668 | 0.0896 | 0.4311 | |
MDA-MB-231 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 873 | 826 | 3064 | 6137 | 665.1 | 116.47 | 15.42 | 8.04 | 492 | 567 | 616 | 649 | 680 | 707 | 733 | 763 | 800 | 0.0893 | 548 | 0.993 | 122.00 | 37.22 | 1 | 0.0979 | 300 | 0.0008 | 64.26 | 7.305 | 0.1764 | 455869.0 | 321000000 | 230000000000 | 169000000000000 | 0.4008 | 0.2360 | 0.0000 | 0.0000 | 0.0004 | 0.0003 | 0.0026 | 0.0000 | 0.0061 | 0.0010 | 0.0299 | 0.0170 | 0.0464 | 0.0304 | 0.0438 | 0.0180 | 0.0520 | 0.0277 | 0.8189 | 0.9056 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0010 | 0.0186 | 0.0166 | 0.0266 | 0.0282 | 0.0190 | 0.0159 | 0.0274 | 0.0239 | 0.9060 | 0.9143 | 0.0000 | 0.0000 | 0.0063 | 0.0000 | 0.0031 | 0.0000 | 0.0563 | 0.0000 | 0.0875 | 0.0000 | 0.1125 | 0.0000 | 0.0906 | 0.0000 | 0.1125 | 0.0000 | 0.5313 | 0.0000 | 0.0006 | 0.0053 | 0.0029 | 0.0135 | 0.0224 | 0.0494 | 0.0371 | 0.0530 | 0.8158 | 9 | 10 | 11 | 12 | 13 | 15 | 16 | 19 | 25 | 0.3326 | 0.28 | 1.109 | 0.7287 | 302.3 | 7707.87 | 246475 | 9230000 | 0.5740 | 0.1078 | 0.0370 | 0.0041 | 0.0648 | 0.0041 | 0.1039 | 0.0126 | 0.1337 | 0.0236 | 0.1566 | 0.0577 | 0.1880 | 0.1004 | 0.1606 | 0.1497 | 0.1151 | 0.2427 | 0.0403 | 0.4050 | 0.0184 | 0.0004 | 0.0317 | 0.0011 | 0.0455 | 0.0041 | 0.0608 | 0.0114 | 0.0782 | 0.0408 | 0.0945 | 0.0788 | 0.0862 | 0.1063 | 0.1277 | 0.1658 | 0.4570 | 0.5914 | 0.0395 | 0.0410 | 0.0482 | 0.0420 | 0.0556 | 0.0400 | 0.0649 | 0.0470 | 0.0803 | 0.0561 | 0.0770 | 0.0681 | 0.0663 | 0.0681 | 0.1071 | 0.1692 | 0.4612 | 0.4685 | 0.0423 | 0.0379 | 0.0347 | 0.0520 | 0.0863 | 0.1089 | 0.1044 | 0.1262 | 0.4073 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 441 | 854 | 1964 | 2153 | 94.0 | 19.07 | 5.89 | 2.19 | 65 | 75 | 84 | 91 | 97 | 103 | 107 | 111 | 116 | 0.2216 | 477 | 0.494 | 340.58 | 73.33 | 1 | 0.5046 | 991 | 0.0224 | 1.75 | 4.105 | 0.5669 | 9205.0 | 931383 | 96800000 | 10300000000 | 0.4309 | 0.2010 | 0.0000 | 0.0000 | 0.0073 | 0.0000 | 0.0147 | 0.0005 | 0.0359 | 0.0058 | 0.0661 | 0.0242 | 0.1184 | 0.0453 | 0.1380 | 0.0353 | 0.1959 | 0.0679 | 0.4237 | 0.8211 | 0.0000 | 0.0000 | 0.0019 | 0.0000 | 0.0013 | 0.0005 | 0.0109 | 0.0052 | 0.0300 | 0.0235 | 0.0504 | 0.0434 | 0.0549 | 0.0314 | 0.0709 | 0.0581 | 0.7797 | 0.8378 | 0.0235 | 0.0909 | 0.0293 | 0.0000 | 0.0704 | 0.1818 | 0.1056 | 0.0909 | 0.1144 | 0.3636 | 0.1525 | 0.2727 | 0.1290 | 0.0000 | 0.1290 | 0.0000 | 0.2463 | 0.0000 | 0.0000 | 0.0027 | 0.0045 | 0.0163 | 0.0506 | 0.0624 | 0.0678 | 0.0850 | 0.7107 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.5417 | 0.29 | 0.926 | 0.8524 | 39.5 | 290.243 | 2305.17 | 19573.6 | 0.5333 | 0.1268 | 0.0126 | 0.0006 | 0.0816 | 0.0054 | 0.1641 | 0.0320 | 0.2592 | 0.0633 | 0.2505 | 0.1333 | 0.1534 | 0.1960 | 0.0621 | 0.2340 | 0.0155 | 0.2117 | 0.0010 | 0.1236 | 0.0000 | 0.0000 | 0.0139 | 0.0011 | 0.0357 | 0.0096 | 0.1130 | 0.0340 | 0.1897 | 0.0919 | 0.2161 | 0.1338 | 0.2254 | 0.1875 | 0.1586 | 0.2953 | 0.0476 | 0.2469 | 0.1946 | 0.4222 | 0.2754 | 0.2667 | 0.2402 | 0.1378 | 0.1718 | 0.1244 | 0.0787 | 0.0400 | 0.0311 | 0.0089 | 0.0062 | 0.0000 | 0.0021 | 0.0000 | 0.0000 | 0.0000 | 0.0076 | 0.0552 | 0.1027 | 0.1986 | 0.2182 | 0.1910 | 0.1171 | 0.0849 | 0.0246 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 715 | 284 | 4349 | 24088 | 89.5 | 13.78 | 5.43 | 2.07 | 73 | 77 | 80 | 84 | 87 | 91 | 97 | 103 | 109 | 0.0418 | 1008 | 0.588 | 324.65 | 84.85 | 1 | 0.2175 | 946 | 0.0394 | 0.86 | 3.496 | 0.6959 | 8200.8 | 769285 | 73900000 | 7250000000 | 0.4494 | 0.2031 | 0.0008 | 0.0000 | 0.0051 | 0.0000 | 0.0102 | 0.0007 | 0.0254 | 0.0044 | 0.0392 | 0.0120 | 0.0621 | 0.0294 | 0.0708 | 0.0204 | 0.1033 | 0.0328 | 0.6830 | 0.9003 | 0.0005 | 0.0000 | 0.0027 | 0.0000 | 0.0056 | 0.0007 | 0.0144 | 0.0037 | 0.0237 | 0.0115 | 0.0345 | 0.0283 | 0.0362 | 0.0170 | 0.0511 | 0.0255 | 0.8312 | 0.9133 | 0.0183 | 0.0800 | 0.0220 | 0.0800 | 0.0661 | 0.0000 | 0.0771 | 0.2400 | 0.0789 | 0.1600 | 0.0881 | 0.0400 | 0.0844 | 0.2800 | 0.1101 | 0.0400 | 0.4550 | 0.0800 | 0.0079 | 0.0173 | 0.0283 | 0.0336 | 0.0378 | 0.0420 | 0.0535 | 0.0991 | 0.6807 | 3 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 0.5147 | 0.30 | 0.895 | 0.8351 | 33.8 | 231.792 | 1719.99 | 13657.8 | 0.5085 | 0.1610 | 0.0301 | 0.0016 | 0.0914 | 0.0107 | 0.1790 | 0.0368 | 0.2367 | 0.0927 | 0.2312 | 0.1792 | 0.1506 | 0.2518 | 0.0667 | 0.2459 | 0.0126 | 0.1425 | 0.0017 | 0.0387 | 0.0000 | 0.0000 | 0.0003 | 0.0001 | 0.0019 | 0.0004 | 0.0124 | 0.0041 | 0.0401 | 0.0133 | 0.1042 | 0.0327 | 0.2310 | 0.0785 | 0.3474 | 0.2650 | 0.2627 | 0.6059 | 0.0142 | 0.0719 | 0.0704 | 0.1807 | 0.1551 | 0.2535 | 0.2061 | 0.2209 | 0.2091 | 0.1486 | 0.1568 | 0.0748 | 0.1088 | 0.0355 | 0.0596 | 0.0115 | 0.0198 | 0.0026 | 0.0004 | 0.0054 | 0.0302 | 0.0848 | 0.1735 | 0.2508 | 0.2509 | 0.1550 | 0.0492 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 995 | 342 | 564 | 6866 | 365.6 | 120.17 | 7.19 | 3.22 | 232 | 252 | 275 | 304 | 342 | 374 | 420 | 483 | 545 | 0.0756 | 519 | 0.945 | 118.23 | 29.12 | 4 | 0.5071 | 286 | 0.0058 | 7.76 | 5.422 | 0.3429 | 148105.0 | 65900000 | 31700000000 | 16200000000000 | 0.3696 | 0.2532 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0194 | 0.0133 | 0.1311 | 0.0421 | 0.2136 | 0.1242 | 0.1505 | 0.0643 | 0.1553 | 0.0931 | 0.3301 | 0.6630 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0083 | 0.0056 | 0.0500 | 0.0297 | 0.0667 | 0.0816 | 0.0444 | 0.0260 | 0.0639 | 0.0464 | 0.7667 | 0.8108 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0114 | 0.0195 | 0.0341 | 0.0779 | 0.0909 | 0.0974 | 0.1250 | 0.0649 | 0.0568 | 0.0779 | 0.1591 | 0.6623 | 0.5227 | 0.0000 | 0.0000 | 0.0000 | 0.0082 | 0.0617 | 0.0864 | 0.0453 | 0.0864 | 0.7119 | 4 | 4 | 5 | 6 | 7 | 7 | 8 | 10 | 12 | 0.0970 | 0.30 | 0.907 | 0.3778 | 62.0 | 621.741 | 7050.74 | 88336.7 | 0.5310 | 0.1386 | 0.0333 | 0.0083 | 0.0940 | 0.0274 | 0.1573 | 0.0625 | 0.2031 | 0.1170 | 0.2115 | 0.1983 | 0.1705 | 0.2399 | 0.0918 | 0.2042 | 0.0329 | 0.1141 | 0.0055 | 0.0284 | 0.0071 | 0.0004 | 0.0280 | 0.0051 | 0.0552 | 0.0227 | 0.0722 | 0.0545 | 0.0905 | 0.0935 | 0.1106 | 0.1358 | 0.1192 | 0.1525 | 0.1513 | 0.1718 | 0.3659 | 0.3639 | 0.0766 | 0.0859 | 0.0697 | 0.0791 | 0.0676 | 0.0846 | 0.0855 | 0.0784 | 0.0907 | 0.0914 | 0.1096 | 0.1153 | 0.1311 | 0.1535 | 0.1809 | 0.1869 | 0.1883 | 0.1248 | 0.0208 | 0.0594 | 0.0898 | 0.1063 | 0.1084 | 0.1039 | 0.0962 | 0.1215 | 0.2938 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 516 | 891 | 618 | 739 | 106.8 | 15.78 | 5.93 | 2.23 | 82 | 92 | 99 | 105 | 109 | 114 | 118 | 121 | 125 | 0.3234 | 239 | 1.055 | 76.24 | 24.70 | 1 | 0.3026 | 187 | 0.0261 | 2.24 | 3.925 | 0.5232 | 11645.2 | 1290000 | 146000000 | 16700000000 | 0.3863 | 0.2434 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0199 | 0.0000 | 0.0358 | 0.0405 | 0.0875 | 0.0631 | 0.1093 | 0.0275 | 0.1590 | 0.0469 | 0.5885 | 0.8220 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0188 | 0.0000 | 0.0282 | 0.0405 | 0.0545 | 0.0631 | 0.0545 | 0.0275 | 0.0395 | 0.0469 | 0.8045 | 0.8220 | 0.1034 | 0.0000 | 0.2414 | 0.0000 | 0.2414 | 0.0000 | 0.2414 | 0.0000 | 0.1034 | 0.0000 | 0.0690 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0277 | 0.0360 | 0.0305 | 0.0637 | 0.0665 | 0.1108 | 0.6648 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.5158 | 0.30 | 0.942 | 0.8384 | 40.2 | 298.797 | 2399.87 | 20613.1 | 0.4399 | 0.1643 | 0.0054 | 0.0000 | 0.0863 | 0.0054 | 0.1563 | 0.0342 | 0.3100 | 0.1081 | 0.2022 | 0.1856 | 0.1725 | 0.2270 | 0.0566 | 0.2378 | 0.0108 | 0.1640 | 0.0000 | 0.0378 | 0.0000 | 0.0000 | 0.0186 | 0.0016 | 0.0557 | 0.0188 | 0.1002 | 0.0518 | 0.1670 | 0.1256 | 0.2041 | 0.1680 | 0.2059 | 0.2135 | 0.1837 | 0.2370 | 0.0649 | 0.1837 | 0.1845 | 0.4878 | 0.2917 | 0.2195 | 0.2440 | 0.2195 | 0.2024 | 0.0732 | 0.0476 | 0.0000 | 0.0298 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0213 | 0.0520 | 0.1348 | 0.1442 | 0.1891 | 0.1915 | 0.1277 | 0.1040 | 0.0355 | |
MDA-MB-231 | 0 | DRAQ5 | 1 | TMRE | 2 | 2 | 2 | 1 | 387 | 777 | 3566 | 6931 | 639.4 | 107.04 | 10.06 | 4.66 | 486 | 547 | 588 | 620 | 651 | 674 | 700 | 732 | 773 | 0.0884 | 613 | 1.124 | 98.72 | 31.38 | 1 | 0.0670 | 239 | 0.0010 | 36.61 | 7.121 | 0.1989 | 420338.0 | 283000000 | 195000000000 | 137000000000000 | 0.3984 | 0.2382 | 0.0011 | 0.0000 | 0.0011 | 0.0000 | 0.0053 | 0.0000 | 0.0083 | 0.0003 | 0.0320 | 0.0164 | 0.0531 | 0.0288 | 0.0531 | 0.0164 | 0.0753 | 0.0257 | 0.7708 | 0.9124 | 0.0007 | 0.0000 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0029 | 0.0003 | 0.0186 | 0.0158 | 0.0258 | 0.0270 | 0.0225 | 0.0141 | 0.0287 | 0.0217 | 0.9000 | 0.9211 | 0.0000 | 0.0000 | 0.0149 | 0.1667 | 0.0446 | 0.0833 | 0.0718 | 0.2500 | 0.0767 | 0.2500 | 0.1287 | 0.2500 | 0.0965 | 0.0000 | 0.1658 | 0.0000 | 0.4010 | 0.0000 | 0.0010 | 0.0005 | 0.0021 | 0.0124 | 0.0361 | 0.0465 | 0.0589 | 0.0780 | 0.7646 | 5 | 7 | 7 | 8 | 9 | 10 | 12 | 13 | 16 | 0.4127 | 0.30 | 1.079 | 0.7896 | 122.9 | 1790.87 | 30353.2 | 582290 | 0.5361 | 0.1291 | 0.0335 | 0.0045 | 0.0959 | 0.0139 | 0.1633 | 0.0252 | 0.2000 | 0.0536 | 0.2138 | 0.0902 | 0.1661 | 0.1532 | 0.0951 | 0.2086 | 0.0264 | 0.2648 | 0.0059 | 0.1859 | 0.0097 | 0.0003 | 0.0311 | 0.0027 | 0.0593 | 0.0058 | 0.0757 | 0.0236 | 0.0929 | 0.0587 | 0.1048 | 0.1040 | 0.1018 | 0.1321 | 0.1193 | 0.1860 | 0.4054 | 0.4869 | 0.0652 | 0.0615 | 0.0666 | 0.0608 | 0.0576 | 0.0615 | 0.0566 | 0.0660 | 0.0756 | 0.0801 | 0.0809 | 0.1008 | 0.0856 | 0.1127 | 0.1365 | 0.1579 | 0.3754 | 0.2987 | 0.0501 | 0.0714 | 0.0772 | 0.0740 | 0.0778 | 0.0730 | 0.0804 | 0.1126 | 0.3836 | |||
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 762 | 189 | 1376 | 10419 | 35.3 | 9.21 | 10.27 | 5.63 | 22 | 26 | 29 | 33 | 36 | 39 | 42 | 44 | 47 | 0.0696 | 725 | 0.931 | 32.02 | 6.00 | 6 | 0.0509 | 70 | 0.0514 | 0.71 | 3.174 | 0.7185 | 1329.9 | 52792.9 | 2180000 | 92900000 | 0.3888 | 0.2401 | 0.0112 | 0.0000 | 0.0224 | 0.0000 | 0.0384 | 0.0041 | 0.0480 | 0.0132 | 0.0880 | 0.0438 | 0.1296 | 0.0661 | 0.1552 | 0.0867 | 0.2224 | 0.1189 | 0.2848 | 0.6672 | 0.0038 | 0.0000 | 0.0029 | 0.0000 | 0.0105 | 0.0023 | 0.0134 | 0.0077 | 0.0335 | 0.0302 | 0.0374 | 0.0294 | 0.0412 | 0.0394 | 0.0766 | 0.0510 | 0.7807 | 0.8399 | 0.0167 | 0.0854 | 0.0143 | 0.1707 | 0.0263 | 0.1341 | 0.0430 | 0.2073 | 0.0740 | 0.1463 | 0.0883 | 0.2073 | 0.0931 | 0.0244 | 0.1551 | 0.0244 | 0.4893 | 0.0000 | 0.0027 | 0.0040 | 0.0121 | 0.0214 | 0.0429 | 0.0402 | 0.0657 | 0.0979 | 0.7131 | 5 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 15 | 0.2596 | 0.30 | 0.975 | 0.6174 | 137.1 | 3359.17 | 189453 | 16100000 | 0.5305 | 0.1486 | 0.0352 | 0.0019 | 0.0945 | 0.0122 | 0.1668 | 0.0289 | 0.2222 | 0.0571 | 0.2112 | 0.0964 | 0.1536 | 0.1503 | 0.0877 | 0.2161 | 0.0244 | 0.2552 | 0.0044 | 0.1819 | 0.0068 | 0.0000 | 0.0230 | 0.0021 | 0.0437 | 0.0082 | 0.0549 | 0.0212 | 0.0735 | 0.0449 | 0.0787 | 0.0675 | 0.1107 | 0.0939 | 0.1744 | 0.1513 | 0.4343 | 0.6109 | 0.0472 | 0.0923 | 0.0513 | 0.1077 | 0.0808 | 0.1294 | 0.1073 | 0.1464 | 0.1292 | 0.1422 | 0.1429 | 0.1316 | 0.1703 | 0.1167 | 0.1551 | 0.0716 | 0.1158 | 0.0621 | 0.0303 | 0.0432 | 0.0455 | 0.0586 | 0.0760 | 0.1103 | 0.1403 | 0.2192 | 0.2767 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 160 | 559 | 777 | 9070 | 142.8 | 24.42 | 9.70 | 3.50 | 112 | 118 | 126 | 133 | 140 | 148 | 158 | 166 | 176 | 0.0568 | 515 | 1.054 | 31.06 | 11.31 | 2 | 0.1055 | 82 | 0.0343 | 0.90 | 3.554 | 0.6764 | 20980.7 | 3170000 | 492000000 | 78100000000 | 0.3567 | 0.2774 | 0.0018 | 0.0000 | 0.0054 | 0.0000 | 0.0108 | 0.0000 | 0.0324 | 0.0052 | 0.0486 | 0.0297 | 0.0845 | 0.0568 | 0.0899 | 0.0375 | 0.1367 | 0.0672 | 0.5899 | 0.8036 | 0.0000 | 0.0000 | 0.0015 | 0.0000 | 0.0060 | 0.0000 | 0.0120 | 0.0051 | 0.0300 | 0.0296 | 0.0556 | 0.0566 | 0.0390 | 0.0335 | 0.0691 | 0.0463 | 0.7868 | 0.8288 | 0.0000 | 0.3333 | 0.0273 | 0.6667 | 0.0545 | 0.0000 | 0.0909 | 0.0000 | 0.0545 | 0.0000 | 0.1273 | 0.0000 | 0.1364 | 0.0000 | 0.1545 | 0.0000 | 0.3545 | 0.0000 | 0.0027 | 0.0082 | 0.0164 | 0.0274 | 0.0521 | 0.0438 | 0.0712 | 0.0904 | 0.6877 | 5 | 7 | 8 | 8 | 9 | 10 | 11 | 13 | 14 | 0.3521 | 0.32 | 0.913 | 0.7078 | 106.3 | 1283.9 | 16775.6 | 233954 | 0.5201 | 0.1454 | 0.0253 | 0.0006 | 0.0903 | 0.0051 | 0.1671 | 0.0191 | 0.2366 | 0.0551 | 0.2191 | 0.1221 | 0.1546 | 0.1819 | 0.0752 | 0.2234 | 0.0261 | 0.2369 | 0.0057 | 0.1558 | 0.0061 | 0.0002 | 0.0215 | 0.0009 | 0.0425 | 0.0040 | 0.0618 | 0.0164 | 0.0849 | 0.0497 | 0.0987 | 0.0844 | 0.1341 | 0.1082 | 0.2235 | 0.1971 | 0.3269 | 0.5392 | 0.0656 | 0.0964 | 0.0810 | 0.1782 | 0.1177 | 0.2345 | 0.1625 | 0.2235 | 0.1694 | 0.1497 | 0.1640 | 0.0679 | 0.1374 | 0.0336 | 0.0780 | 0.0110 | 0.0243 | 0.0051 | 0.0347 | 0.0481 | 0.0556 | 0.0753 | 0.0996 | 0.1448 | 0.1879 | 0.2108 | 0.1433 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 181 | 254 | 1614 | 11324 | 1117.5 | 296.73 | 9.91 | 3.01 | 735 | 828 | 914 | 1000 | 1089 | 1176 | 1265 | 1423 | 1565 | 0.0770 | 872 | 1.072 | 79.08 | 22.56 | 2 | 0.1121 | 181 | 0.0011 | 52.02 | 6.977 | 0.1957 | 1340000.0 | 1700000000 | 2270000000000 | 3.16E+15 | 0.3925 | 0.2330 | 0.0013 | 0.0000 | 0.0000 | 0.0007 | 0.0000 | 0.0043 | 0.0090 | 0.0078 | 0.0859 | 0.0456 | 0.1538 | 0.0820 | 0.1013 | 0.0520 | 0.1115 | 0.0834 | 0.5372 | 0.7242 | 0.0009 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0026 | 0.0043 | 0.0058 | 0.0445 | 0.0358 | 0.0676 | 0.0588 | 0.0360 | 0.0371 | 0.0668 | 0.0543 | 0.7800 | 0.8056 | 0.0000 | 0.0000 | 0.0000 | 0.0062 | 0.0000 | 0.0124 | 0.0103 | 0.0248 | 0.0490 | 0.0745 | 0.0979 | 0.1242 | 0.0515 | 0.0745 | 0.0670 | 0.1304 | 0.7242 | 0.5528 | 0.0000 | 0.0000 | 0.0013 | 0.0066 | 0.0584 | 0.0717 | 0.0491 | 0.0704 | 0.7424 | 6 | 7 | 8 | 9 | 10 | 11 | 11 | 12 | 14 | 0.4427 | 0.33 | 0.894 | 0.7893 | 107.3 | 1247.66 | 15428.7 | 201459 | 0.5329 | 0.1343 | 0.0090 | 0.0001 | 0.0432 | 0.0015 | 0.1219 | 0.0064 | 0.2092 | 0.0237 | 0.2630 | 0.0647 | 0.2046 | 0.1320 | 0.1129 | 0.2428 | 0.0316 | 0.3164 | 0.0048 | 0.2124 | 0.0001 | 0.0000 | 0.0019 | 0.0002 | 0.0112 | 0.0008 | 0.0360 | 0.0079 | 0.0843 | 0.0254 | 0.1595 | 0.0409 | 0.2364 | 0.0926 | 0.2711 | 0.2669 | 0.1995 | 0.5654 | 0.0875 | 0.2991 | 0.1970 | 0.2991 | 0.2239 | 0.2057 | 0.2071 | 0.1218 | 0.1517 | 0.0503 | 0.0847 | 0.0160 | 0.0376 | 0.0044 | 0.0092 | 0.0036 | 0.0012 | 0.0000 | 0.0072 | 0.0439 | 0.0969 | 0.1605 | 0.2046 | 0.1989 | 0.1608 | 0.0959 | 0.0313 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 902 | 439 | 9462 | 17615 | 66.2 | 18.80 | 11.63 | 7.94 | 45 | 48 | 51 | 57 | 63 | 69 | 76 | 85 | 93 | 0.0582 | 1025 | 0.806 | 93.06 | 26.68 | 0 | 0.0260 | 246 | 0.0396 | 0.80 | 3.627 | 0.7208 | 4738.0 | 364637 | 29900000 | 2590000000 | 0.4090 | 0.2322 | 0.0114 | 0.0009 | 0.0137 | 0.0014 | 0.0190 | 0.0032 | 0.0307 | 0.0089 | 0.0497 | 0.0193 | 0.0678 | 0.0417 | 0.0898 | 0.0415 | 0.1269 | 0.0742 | 0.5909 | 0.8088 | 0.0052 | 0.0000 | 0.0064 | 0.0002 | 0.0081 | 0.0003 | 0.0109 | 0.0024 | 0.0165 | 0.0081 | 0.0215 | 0.0205 | 0.0284 | 0.0132 | 0.0370 | 0.0319 | 0.8659 | 0.9234 | 0.0061 | 0.0140 | 0.0065 | 0.0220 | 0.0105 | 0.0451 | 0.0252 | 0.0762 | 0.0304 | 0.1062 | 0.0527 | 0.1333 | 0.0641 | 0.1283 | 0.0933 | 0.1413 | 0.7112 | 0.3337 | 0.0026 | 0.0049 | 0.0086 | 0.0123 | 0.0283 | 0.0339 | 0.0416 | 0.0706 | 0.7972 | 5 | 6 | 7 | 8 | 9 | 10 | 12 | 15 | 22 | 0.2867 | 0.33 | 1.922 | 0.8442 | 198.3 | 4862.52 | 154893 | 5820000 | 0.5138 | 0.1400 | 0.0871 | 0.0128 | 0.1401 | 0.0280 | 0.1505 | 0.0586 | 0.1491 | 0.0912 | 0.1521 | 0.1375 | 0.1294 | 0.1665 | 0.1167 | 0.1770 | 0.0606 | 0.1781 | 0.0146 | 0.1503 | 0.0408 | 0.0059 | 0.0668 | 0.0174 | 0.0671 | 0.0381 | 0.0575 | 0.0614 | 0.0582 | 0.0937 | 0.0540 | 0.1156 | 0.0645 | 0.1142 | 0.0925 | 0.1136 | 0.4986 | 0.4402 | 0.0246 | 0.0157 | 0.0222 | 0.0242 | 0.0309 | 0.0310 | 0.0415 | 0.0336 | 0.0492 | 0.0529 | 0.0632 | 0.0663 | 0.0719 | 0.0777 | 0.1169 | 0.1326 | 0.5796 | 0.5660 | 0.0564 | 0.0389 | 0.0353 | 0.0306 | 0.0484 | 0.0603 | 0.0728 | 0.0984 | 0.5589 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1074 | 469 | 856 | 4211 | 285.4 | 67.25 | 6.42 | 2.65 | 204 | 219 | 238 | 258 | 279 | 298 | 314 | 342 | 392 | 0.0912 | 384 | 0.307 | 78.41 | 12.65 | 1 | 0.3540 | 303 | 0.0100 | 2.29 | 4.835 | 0.5114 | 85984.1 | 27300000 | 9080000000 | 3150000000000 | 0.3537 | 0.2878 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0190 | 0.0026 | 0.0634 | 0.0408 | 0.1142 | 0.0829 | 0.0846 | 0.0421 | 0.1078 | 0.0523 | 0.6110 | 0.7793 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0078 | 0.0012 | 0.0310 | 0.0315 | 0.0620 | 0.0619 | 0.0326 | 0.0245 | 0.0419 | 0.0304 | 0.8248 | 0.8505 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0116 | 0.0139 | 0.0407 | 0.0139 | 0.0407 | 0.1389 | 0.0872 | 0.1389 | 0.0814 | 0.0694 | 0.0930 | 0.1250 | 0.6453 | 0.5000 | 0.0000 | 0.0000 | 0.0025 | 0.0100 | 0.0549 | 0.0549 | 0.0499 | 0.0998 | 0.7282 | 3 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 10 | 0.0710 | 0.33 | 0.864 | 0.2971 | 48.3 | 412.798 | 3958 | 42046.3 | 0.4542 | 0.1770 | 0.0146 | 0.0016 | 0.0652 | 0.0082 | 0.1429 | 0.0216 | 0.2233 | 0.0554 | 0.2280 | 0.0976 | 0.2045 | 0.1628 | 0.0871 | 0.2473 | 0.0323 | 0.2561 | 0.0021 | 0.1494 | 0.0003 | 0.0000 | 0.0085 | 0.0008 | 0.0241 | 0.0043 | 0.0564 | 0.0112 | 0.1146 | 0.0394 | 0.1580 | 0.0765 | 0.1970 | 0.1501 | 0.1932 | 0.2793 | 0.2479 | 0.4384 | 0.0927 | 0.1488 | 0.1418 | 0.1187 | 0.1354 | 0.1116 | 0.1297 | 0.1259 | 0.1088 | 0.1731 | 0.1128 | 0.1173 | 0.1225 | 0.0959 | 0.0798 | 0.0658 | 0.0766 | 0.0429 | 0.0125 | 0.0467 | 0.0780 | 0.1010 | 0.1263 | 0.1364 | 0.1335 | 0.1557 | 0.2100 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1103 | 521 | 38572 | 41531 | 83.7 | 70.09 | 7.10 | 2.74 | 45 | 48 | 50 | 53 | 56 | 62 | 73 | 98 | 152 | 0.0457 | 1898 | 0.782 | 128.16 | 45.34 | 3 | 0.0101 | 390 | 0.0492 | 1.50 | 4.084 | 0.6882 | 11919.8 | 2870000 | 920000000 | 334000000000 | 0.4510 | 0.1895 | 0.0109 | 0.0089 | 0.0164 | 0.0172 | 0.0246 | 0.0246 | 0.0351 | 0.0389 | 0.0605 | 0.0504 | 0.0801 | 0.0590 | 0.0958 | 0.0673 | 0.1409 | 0.0885 | 0.5357 | 0.6452 | 0.0040 | 0.0067 | 0.0055 | 0.0130 | 0.0089 | 0.0188 | 0.0105 | 0.0286 | 0.0183 | 0.0354 | 0.0237 | 0.0412 | 0.0271 | 0.0468 | 0.0418 | 0.0594 | 0.8604 | 0.7500 | 0.0015 | 0.0009 | 0.0027 | 0.0019 | 0.0047 | 0.0041 | 0.0104 | 0.0090 | 0.0173 | 0.0159 | 0.0259 | 0.0282 | 0.0314 | 0.0309 | 0.0401 | 0.0398 | 0.8660 | 0.8695 | 0.0020 | 0.0024 | 0.0056 | 0.0088 | 0.0174 | 0.0214 | 0.0294 | 0.0366 | 0.8764 | 4 | 5 | 6 | 6 | 7 | 8 | 8 | 9 | 11 | 0.4747 | 0.33 | 1.180 | 0.8414 | 57.9 | 527.37 | 5295.83 | 58155.7 | 0.4995 | 0.1829 | 0.0184 | 0.0024 | 0.0723 | 0.0096 | 0.1551 | 0.0301 | 0.2242 | 0.0749 | 0.2394 | 0.1555 | 0.1742 | 0.2423 | 0.0889 | 0.2556 | 0.0251 | 0.1713 | 0.0024 | 0.0583 | 0.0022 | 0.0001 | 0.0106 | 0.0010 | 0.0291 | 0.0053 | 0.0623 | 0.0178 | 0.1060 | 0.0556 | 0.1606 | 0.1162 | 0.2066 | 0.1940 | 0.2316 | 0.2914 | 0.1910 | 0.3187 | 0.0905 | 0.1632 | 0.1612 | 0.2060 | 0.1796 | 0.1882 | 0.1754 | 0.1469 | 0.1412 | 0.1102 | 0.1007 | 0.0685 | 0.0624 | 0.0461 | 0.0489 | 0.0412 | 0.0401 | 0.0296 | 0.0110 | 0.0392 | 0.0830 | 0.1233 | 0.1517 | 0.1724 | 0.1677 | 0.1502 | 0.1015 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 555 | 532 | 3465 | 14759 | 319.8 | 107.54 | 6.73 | 2.27 | 198 | 221 | 243 | 273 | 310 | 350 | 374 | 394 | 435 | 0.0700 | 1033 | 1.221 | 77.39 | 27.66 | 2 | 0.0543 | 188 | 0.0057 | 5.18 | 5.576 | 0.4523 | 113808.0 | 45100000 | 19800000000 | 9650000000000 | 0.4430 | 0.1901 | 0.0028 | 0.0000 | 0.0063 | 0.0000 | 0.0042 | 0.0017 | 0.0245 | 0.0068 | 0.0756 | 0.0345 | 0.1436 | 0.0519 | 0.1289 | 0.0420 | 0.1646 | 0.0615 | 0.4496 | 0.8016 | 0.0004 | 0.0000 | 0.0009 | 0.0000 | 0.0004 | 0.0012 | 0.0105 | 0.0031 | 0.0285 | 0.0271 | 0.0558 | 0.0389 | 0.0378 | 0.0249 | 0.0470 | 0.0408 | 0.8187 | 0.8639 | 0.0106 | 0.0000 | 0.0153 | 0.0071 | 0.0188 | 0.0035 | 0.0259 | 0.0390 | 0.0506 | 0.0887 | 0.0576 | 0.0957 | 0.0682 | 0.0780 | 0.0988 | 0.0993 | 0.6541 | 0.5887 | 0.0000 | 0.0024 | 0.0018 | 0.0152 | 0.0328 | 0.0425 | 0.0334 | 0.0468 | 0.8251 | 4 | 5 | 6 | 6 | 7 | 7 | 8 | 9 | 10 | 0.0844 | 0.35 | 0.898 | 0.3300 | 50.5 | 413.246 | 3661.4 | 35082.4 | 0.5392 | 0.1292 | 0.0068 | 0.0003 | 0.0451 | 0.0042 | 0.1067 | 0.0171 | 0.1894 | 0.0476 | 0.2341 | 0.0957 | 0.2205 | 0.1698 | 0.1356 | 0.2507 | 0.0525 | 0.2678 | 0.0093 | 0.1466 | 0.0014 | 0.0002 | 0.0128 | 0.0021 | 0.0344 | 0.0077 | 0.0739 | 0.0219 | 0.1043 | 0.0520 | 0.1474 | 0.0981 | 0.1623 | 0.1436 | 0.2138 | 0.2421 | 0.2497 | 0.4324 | 0.1133 | 0.1976 | 0.1372 | 0.2142 | 0.1664 | 0.1783 | 0.1654 | 0.1636 | 0.1518 | 0.1123 | 0.1186 | 0.0744 | 0.0801 | 0.0372 | 0.0458 | 0.0160 | 0.0213 | 0.0064 | 0.0167 | 0.0531 | 0.0922 | 0.1109 | 0.1310 | 0.1500 | 0.1506 | 0.1588 | 0.1366 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1026 | 526 | 1774 | 10377 | 333.7 | 82.77 | 7.07 | 6.95 | 228 | 252 | 275 | 299 | 328 | 356 | 381 | 404 | 456 | 0.0754 | 782 | 1.019 | 63.03 | 17.72 | 1 | 0.0902 | 160 | 0.0074 | 2.20 | 5.116 | 0.5219 | 118176.0 | 44200000 | 17400000000 | 7100000000000 | 0.3704 | 0.2523 | 0.0000 | 0.0000 | 0.0022 | 0.0000 | 0.0044 | 0.0018 | 0.0196 | 0.0031 | 0.0480 | 0.0270 | 0.0981 | 0.0590 | 0.0960 | 0.0277 | 0.1156 | 0.0522 | 0.6161 | 0.8291 | 0.0000 | 0.0000 | 0.0008 | 0.0000 | 0.0015 | 0.0006 | 0.0077 | 0.0006 | 0.0216 | 0.0198 | 0.0448 | 0.0475 | 0.0309 | 0.0158 | 0.0394 | 0.0300 | 0.8533 | 0.8858 | 0.0000 | 0.0070 | 0.0026 | 0.0000 | 0.0159 | 0.0211 | 0.0265 | 0.0493 | 0.0688 | 0.0563 | 0.0688 | 0.0634 | 0.0794 | 0.1197 | 0.0926 | 0.1127 | 0.6455 | 0.5704 | 0.0000 | 0.0012 | 0.0035 | 0.0106 | 0.0307 | 0.0507 | 0.0460 | 0.0507 | 0.8066 | 4 | 4 | 5 | 5 | 6 | 7 | 7 | 8 | 9 | 0.0683 | 0.36 | 0.960 | 0.2803 | 98.4 | 3645.61 | 211535 | 13700000 | 0.5870 | 0.1077 | 0.0219 | 0.0000 | 0.0918 | 0.0034 | 0.2036 | 0.0218 | 0.2478 | 0.0615 | 0.2315 | 0.1441 | 0.1344 | 0.2346 | 0.0524 | 0.2632 | 0.0151 | 0.1992 | 0.0014 | 0.0723 | 0.0070 | 0.0001 | 0.0372 | 0.0017 | 0.1009 | 0.0115 | 0.1433 | 0.0351 | 0.1866 | 0.1006 | 0.1797 | 0.1701 | 0.1357 | 0.2256 | 0.0991 | 0.2326 | 0.1105 | 0.2226 | 0.2165 | 0.2377 | 0.1957 | 0.1575 | 0.1447 | 0.1137 | 0.0919 | 0.0699 | 0.0705 | 0.0657 | 0.0566 | 0.0428 | 0.0334 | 0.0323 | 0.0340 | 0.0396 | 0.1567 | 0.2409 | 0.0252 | 0.0972 | 0.1538 | 0.1674 | 0.1709 | 0.1299 | 0.1019 | 0.0664 | 0.0874 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 815 | 163 | 2938 | 15825 | 562.8 | 165.66 | 10.78 | 7.31 | 288 | 401 | 494 | 571 | 620 | 652 | 677 | 696 | 723 | 0.0577 | 913 | 0.956 | 43.93 | 14.04 | 1 | 0.0388 | 114 | 0.0035 | 13.77 | 6.195 | 0.3459 | 344227.0 | 221000000 | 147000000000 | 100000000000000 | 0.3768 | 0.2427 | 0.0046 | 0.0000 | 0.0069 | 0.0000 | 0.0069 | 0.0004 | 0.0299 | 0.0021 | 0.0851 | 0.0207 | 0.1219 | 0.0435 | 0.0913 | 0.0236 | 0.1296 | 0.0464 | 0.5238 | 0.8632 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0023 | 0.0016 | 0.0213 | 0.0175 | 0.0344 | 0.0358 | 0.0222 | 0.0179 | 0.0376 | 0.0350 | 0.8822 | 0.8921 | 0.0022 | 0.0000 | 0.0078 | 0.0100 | 0.0111 | 0.0200 | 0.0388 | 0.0200 | 0.0543 | 0.0800 | 0.1008 | 0.1300 | 0.1008 | 0.0700 | 0.1274 | 0.1400 | 0.5570 | 0.5300 | 0.0006 | 0.0000 | 0.0000 | 0.0050 | 0.0233 | 0.0417 | 0.0267 | 0.0389 | 0.8639 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 19 | 0.2362 | 0.38 | 1.298 | 0.6613 | 169.5 | 3950.18 | 122472 | 4500000 | 0.5976 | 0.1040 | 0.0323 | 0.0020 | 0.0756 | 0.0106 | 0.1133 | 0.0336 | 0.1438 | 0.0726 | 0.1811 | 0.1062 | 0.1857 | 0.1514 | 0.1597 | 0.2027 | 0.0873 | 0.2334 | 0.0211 | 0.1876 | 0.0202 | 0.0012 | 0.0489 | 0.0067 | 0.0693 | 0.0257 | 0.0868 | 0.0568 | 0.1051 | 0.0848 | 0.1135 | 0.1256 | 0.1228 | 0.1539 | 0.1364 | 0.1840 | 0.2969 | 0.3614 | 0.0929 | 0.0470 | 0.0631 | 0.0212 | 0.0423 | 0.0131 | 0.0317 | 0.0217 | 0.0372 | 0.0359 | 0.0533 | 0.0606 | 0.0451 | 0.0526 | 0.0776 | 0.0773 | 0.5568 | 0.6705 | 0.0675 | 0.0951 | 0.0928 | 0.0982 | 0.0980 | 0.0940 | 0.0648 | 0.0545 | 0.3351 | |
MCF7 | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 214 | 329 | 2935 | 11303 | 279.9 | 61.40 | 6.40 | 2.56 | 193 | 217 | 240 | 262 | 283 | 300 | 320 | 339 | 363 | 0.0572 | 646 | 0.707 | 220.60 | 68.41 | 1 | 0.2290 | 672 | 0.0038 | 5.82 | 5.792 | 0.3874 | 82100.6 | 25100000 | 7920000000 | 2580000000000 | 0.3742 | 0.2640 | 0.0012 | 0.0000 | 0.0055 | 0.0000 | 0.0068 | 0.0003 | 0.0197 | 0.0035 | 0.0419 | 0.0219 | 0.0653 | 0.0299 | 0.0635 | 0.0285 | 0.1054 | 0.0597 | 0.6907 | 0.8563 | 0.0009 | 0.0000 | 0.0018 | 0.0000 | 0.0013 | 0.0003 | 0.0075 | 0.0027 | 0.0168 | 0.0196 | 0.0266 | 0.0240 | 0.0239 | 0.0192 | 0.0350 | 0.0343 | 0.8862 | 0.8998 | 0.0031 | 0.1875 | 0.0126 | 0.2813 | 0.0173 | 0.3750 | 0.0346 | 0.0938 | 0.0456 | 0.0625 | 0.0566 | 0.0000 | 0.0629 | 0.0000 | 0.0849 | 0.0000 | 0.6824 | 0.0000 | 0.0013 | 0.0020 | 0.0059 | 0.0092 | 0.0277 | 0.0323 | 0.0323 | 0.0554 | 0.8339 | 3 | 4 | 5 | 6 | 6 | 7 | 8 | 9 | 10 | 0.4396 | 0.38 | 1.169 | 0.8081 | 47.5 | 391.249 | 3512.14 | 33881.8 | 0.4867 | 0.1660 | 0.0087 | 0.0004 | 0.0533 | 0.0075 | 0.1339 | 0.0348 | 0.2382 | 0.1039 | 0.2579 | 0.1830 | 0.1883 | 0.2424 | 0.0921 | 0.2426 | 0.0230 | 0.1419 | 0.0046 | 0.0434 | 0.0002 | 0.0000 | 0.0018 | 0.0009 | 0.0097 | 0.0035 | 0.0393 | 0.0162 | 0.0799 | 0.0427 | 0.1426 | 0.0876 | 0.2155 | 0.1902 | 0.2757 | 0.3292 | 0.2352 | 0.3297 | 0.0810 | 0.1861 | 0.1648 | 0.2753 | 0.2049 | 0.2537 | 0.1900 | 0.1433 | 0.1511 | 0.0792 | 0.1073 | 0.0385 | 0.0628 | 0.0186 | 0.0300 | 0.0043 | 0.0081 | 0.0009 | 0.0035 | 0.0243 | 0.0659 | 0.1244 | 0.1728 | 0.2058 | 0.2030 | 0.1370 | 0.0633 | |
MCF 10A | A443654 | 10 | uM | DRAQ5 | 1 | TMRE | 2 | 1 | 11 | 1 | 1165 | 419 | 423 | 1848 | 89.8 | 13.38 | 5.99 | 2.24 | 70 | 76 | 82 | 87 | 92 | 96 | 99 | 102 | 106 | 0.1580 | 292 | 0.987 | 101.21 | 28.84 | 2 | 0.5816 | 246 | 0.0855 | 0.62 | 2.720 | 0.7418 | 8238.7 | 771134 | 73500000 | 7110000000 | 0.4178 | 0.2216 | 0.0000 | 0.0000 | 0.0060 | 0.0000 | 0.0149 | 0.0000 | 0.0268 | 0.0071 | 0.0893 | 0.0567 | 0.1220 | 0.0946 | 0.1369 | 0.0520 | 0.1964 | 0.0827 | 0.4077 | 0.7069 | 0.0000 | 0.0000 | 0.0054 | 0.0000 | 0.0109 | 0.0000 | 0.0218 | 0.0071 | 0.0708 | 0.0567 | 0.0627 | 0.0946 | 0.0518 | 0.0520 | 0.0681 | 0.0827 | 0.7084 | 0.7069 | 0.0968 | 0.0000 | 0.2581 | 0.0000 | 0.2581 | 0.0000 | 0.1613 | 0.0000 | 0.0968 | 0.0000 | 0.0968 | 0.0000 | 0.0323 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0000 | 0.0128 | 0.0213 | 0.0383 | 0.0553 | 0.0596 | 0.0851 | 0.1532 | 0.5745 | 3 | 4 | 5 | 6 | 6 | 6 | 7 | 8 | 9 | 0.0815 | 0.39 | 0.827 | 0.2673 | 40.9 | 306.966 | 2499.9 | 21880.8 | 0.5165 | 0.1403 | 0.0116 | 0.0008 | 0.0474 | 0.0055 | 0.1063 | 0.0444 | 0.2358 | 0.1014 | 0.2716 | 0.1846 | 0.1884 | 0.2472 | 0.1011 | 0.2274 | 0.0316 | 0.1450 | 0.0063 | 0.0436 | 0.0000 | 0.0000 | 0.0041 | 0.0020 | 0.0186 | 0.0118 | 0.0592 | 0.0341 | 0.1171 | 0.1076 | 0.1860 | 0.1594 | 0.2404 | 0.2270 | 0.2424 | 0.2782 | 0.1322 | 0.1798 | 0.1036 | 0.3053 | 0.2490 | 0.2824 | 0.2829 | 0.1756 | 0.1972 | 0.0954 | 0.1056 | 0.0916 | 0.0418 | 0.0305 | 0.0179 | 0.0153 | 0.0020 | 0.0038 | 0.0000 | 0.0000 | 0.0026 | 0.0290 | 0.0729 | 0.1747 | 0.2186 | 0.2151 | 0.1449 | 0.1010 | 0.0413 | |
SK-BR-3 | Barasertib | 0.12 | uM | DRAQ5 | 1 | TMRE | 2 | 2 | 15 | 1 | 953 | 241 | 4452 | 16651 | 514.3 | 202.79 | 16.75 | 22.48 | 264 | 314 | 365 | 425 | 496 | 574 | 650 | 721 | 776 | 0.0610 | 1016 | 0.831 | 150.81 | 30.46 | 9 | 0.0806 | 359 | 0.0007 | 46.67 | 7.524 | 0.1977 | 305620.0 | 203000000 | 146000000000 | 112000000000000 | 0.3891 | 0.2375 | 0.0008 | 0.0022 | 0.0000 | 0.0000 | 0.0142 | 0.0022 | 0.0334 | 0.0103 | 0.0943 | 0.0357 | 0.1060 | 0.0600 | 0.1018 | 0.0527 | 0.1277 | 0.0681 | 0.5217 | 0.7688 | 0.0000 | 0.0003 | 0.0000 | 0.0000 | 0.0015 | 0.0003 | 0.0036 | 0.0052 | 0.0259 | 0.0196 | 0.0353 | 0.0304 | 0.0230 | 0.0232 | 0.0383 | 0.0312 | 0.8724 | 0.8898 | 0.0000 | 0.0000 | 0.0000 | 0.0044 | 0.0019 | 0.0044 | 0.0045 | 0.0166 | 0.0408 | 0.0376 | 0.0388 | 0.0564 | 0.0323 | 0.0431 | 0.0511 | 0.0818 | 0.8305 | 0.7558 | 0.0000 | 0.0000 | 0.0000 | 0.0067 | 0.0262 | 0.0419 | 0.0295 | 0.0409 | 0.8548 | 6 | 7 | 8 | 9 | 11 | 14 | 17 | 22 | 30 | 0.1712 | 0.40 | 1.575 | 0.6158 | 785.9 | 143855 | 50100000 | 21000000000 | 0.6171 | 0.0868 | 0.0605 | 0.0488 | 0.0678 | 0.0590 | 0.0946 | 0.0585 | 0.1398 | 0.0738 | 0.1565 | 0.0814 | 0.1773 | 0.0904 | 0.1603 | 0.1323 | 0.1067 | 0.1903 | 0.0365 | 0.2655 | 0.0178 | 0.0287 | 0.0157 | 0.0319 | 0.0185 | 0.0277 | 0.0267 | 0.0319 | 0.0491 | 0.0406 | 0.0697 | 0.0463 | 0.0717 | 0.0582 | 0.1168 | 0.0921 | 0.6140 | 0.6425 | 0.0160 | 0.0168 | 0.0214 | 0.0291 | 0.0295 | 0.0412 | 0.0447 | 0.0496 | 0.0736 | 0.0814 | 0.0894 | 0.0941 | 0.1054 | 0.1129 | 0.1416 | 0.1313 | 0.4783 | 0.4436 | 0.0152 | 0.0164 | 0.0269 | 0.0290 | 0.0574 | 0.0696 | 0.0884 | 0.1384 | 0.5589 |