Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
---|---|---|---|---|---|---|---|---|---|---|---|---|
SB590885 | C32 | 0.3160 | uM | 24 | hr | 2219 | 486 | 1.0020 | 0.9712 | 0.2190 | 0.2246 | 3 |
SB590885 | C32 | 0.3160 | uM | 24 | hr | 2219 | 460 | 1.0170 | 0.9712 | 0.2073 | 0.2246 | 4 |
SB590885 | C32 | 0.3160 | uM | 48 | hr | 2033 | 401 | 0.7941 | 0.8577 | 0.1973 | 0.1894 | 1 |
SB590885 | C32 | 0.3160 | uM | 48 | hr | 1967 | 404 | 0.7605 | 0.8577 | 0.2054 | 0.1894 | 2 |
SB590885 | C32 | 0.3160 | uM | 48 | hr | 2272 | 419 | 0.9016 | 0.8577 | 0.1844 | 0.1894 | 3 |
SB590885 | C32 | 0.3160 | uM | 48 | hr | 2415 | 412 | 0.9746 | 0.8577 | 0.1706 | 0.1894 | 4 |
SB590885 | C32 | 0.3160 | uM | 72 | hr | 1227 | 361 | 0.3781 | 0.4360 | 0.2942 | 0.2745 | 1 |
SB590885 | C32 | 0.3160 | uM | 72 | hr | 1376 | 382 | 0.4340 | 0.4360 | 0.2776 | 0.2745 | 2 |
SB590885 | C32 | 0.3160 | uM | 72 | hr | 1431 | 361 | 0.4672 | 0.4360 | 0.2523 | 0.2745 | 3 |
SB590885 | C32 | 0.3160 | uM | 72 | hr | 1465 | 401 | 0.4646 | 0.4360 | 0.2737 | 0.2745 | 4 |
SB590885 | C32 | 1.0000 | uM | 24 | hr | 1866 | 424 | 0.8337 | 0.8421 | 0.2272 | 0.2404 | 1 |
SB590885 | C32 | 1.0000 | uM | 24 | hr | 1995 | 454 | 0.8909 | 0.8421 | 0.2276 | 0.2404 | 2 |
SB590885 | C32 | 1.0000 | uM | 24 | hr | 1840 | 455 | 0.8008 | 0.8421 | 0.2473 | 0.2404 | 3 |
SB590885 | C32 | 1.0000 | uM | 24 | hr | 1969 | 511 | 0.8430 | 0.8421 | 0.2595 | 0.2404 | 4 |
SB590885 | C32 | 1.0000 | uM | 48 | hr | 1752 | 701 | 0.5114 | 0.5507 | 0.4001 | 0.3802 | 1 |
SB590885 | C32 | 1.0000 | uM | 48 | hr | 1618 | 619 | 0.4861 | 0.5507 | 0.3826 | 0.3802 | 2 |
SB590885 | C32 | 1.0000 | uM | 48 | hr | 1951 | 695 | 0.6111 | 0.5507 | 0.3562 | 0.3802 | 3 |
SB590885 | C32 | 1.0000 | uM | 48 | hr | 1975 | 754 | 0.5941 | 0.5507 | 0.3818 | 0.3802 | 4 |
SB590885 | C32 | 1.0000 | uM | 72 | hr | 1164 | 580 | 0.2550 | 0.2758 | 0.4983 | 0.4735 | 1 |
SB590885 | C32 | 1.0000 | uM | 72 | hr | 1221 | 590 | 0.2755 | 0.2758 | 0.4832 | 0.4735 | 2 |
SB590885 | C32 | 1.0000 | uM | 72 | hr | 1217 | 555 | 0.2890 | 0.2758 | 0.4560 | 0.4735 | 3 |
SB590885 | C32 | 1.0000 | uM | 72 | hr | 1196 | 546 | 0.2838 | 0.2758 | 0.4565 | 0.4735 | 4 |
SB590885 | C32 | 3.1600 | uM | 24 | hr | 1858 | 507 | 0.7811 | 0.7788 | 0.2729 | 0.2708 | 1 |
SB590885 | C32 | 3.1600 | uM | 24 | hr | 1897 | 517 | 0.7979 | 0.7788 | 0.2725 | 0.2708 | 2 |
SB590885 | C32 | 3.1600 | uM | 24 | hr | 1844 | 487 | 0.7846 | 0.7788 | 0.2641 | 0.2708 | 3 |