Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
SB590885 C32 3.1600
uM
 24
hr
 1790 490 0.7516 0.7788 0.2737 0.2708 4
SB590885 C32 3.1600
uM
 48
hr
 1569 840 0.3547 0.3996 0.5354 0.5238 1
SB590885 C32 3.1600
uM
 48
hr
 1545 846 0.3401 0.3996 0.5476 0.5238 2
SB590885 C32 3.1600
uM
 48
hr
 1850 944 0.4408 0.3996 0.5103 0.5238 3
SB590885 C32 3.1600
uM
 48
hr
 1909 958 0.4627 0.3996 0.5018 0.5238 4
SB590885 C32 3.1600
uM
 72
hr
 1142 655 0.2126 0.2092 0.5736 0.5417 1
SB590885 C32 3.1600
uM
 72
hr
 987 500 0.2126 0.2092 0.5066 0.5417 2
SB590885 C32 3.1600
uM
 72
hr
 1083 633 0.1965 0.2092 0.5845 0.5417 3
SB590885 C32 3.1600
uM
 72
hr
 990 497 0.2153 0.2092 0.5020 0.5417 4
PLX-4720 C32 0.0032
uM
 24
hr
 1877 158 0.9939 0.9798 0.0842 0.0874 1
PLX-4720 C32 0.0032
uM
 24
hr
 1816 151 0.9626 0.9798 0.0832 0.0874 2
PLX-4720 C32 0.0032
uM
 24
hr
 1952 167 1.0320 0.9798 0.0856 0.0874 3
PLX-4720 C32 0.0032
uM
 24
hr
 1782 172 0.9308 0.9798 0.0965 0.0874 4
PLX-4720 C32 0.0032
uM
 48
hr
 2479 281 1.0695 1.1088 0.1134 0.0967 1
PLX-4720 C32 0.0032
uM
 48
hr
 2443 252 1.0661 1.1088 0.1032 0.0967 2
PLX-4720 C32 0.0032
uM
 48
hr
 2526 219 1.1225 1.1088 0.0867 0.0967 3
PLX-4720 C32 0.0032
uM
 48
hr
 2640 221 1.1770 1.1088 0.0837 0.0967 4
PLX-4720 C32 0.0032
uM
 72
hr
 2292 171 0.9260 0.9573 0.0746 0.0846 1
PLX-4720 C32 0.0032
uM
 72
hr
 2032 185 0.8064 0.9573 0.0910 0.0846 2
PLX-4720 C32 0.0032
uM
 72
hr
 2731 233 1.0906 0.9573 0.0853 0.0846 3
PLX-4720 C32 0.0032
uM
 72
hr
 2525 221 1.0059 0.9573 0.0875 0.0846 4
PLX-4720 C32 0.0100
uM
 24
hr
 1893 277 0.9343 1.0031 0.1463 0.1207 1
PLX-4720 C32 0.0100
uM
 24
hr
 2014 222 1.0361 1.0031 0.1102 0.1207 2
PLX-4720 C32 0.0100
uM
 24
hr
 2007 217 1.0349 1.0031 0.1081 0.1207 3
PLX-4720 C32 0.0100
uM
 24
hr
 1975 233 1.0072 1.0031 0.1180 0.1207 4