Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib C32 0.3160
uM
 24
hr
 1922 416 0.8707 0.9384 0.2164 0.2148 1
Selumetinib C32 0.3160
uM
 24
hr
 2162 495 0.9638 0.9384 0.2290 0.2148 2
Selumetinib C32 0.3160
uM
 24
hr
 1987 345 0.9493 0.9384 0.1736 0.2148 3
Selumetinib C32 0.3160
uM
 24
hr
 2207 530 0.9696 0.9384 0.2401 0.2148 4
Selumetinib C32 0.3160
uM
 48
hr
 1678 517 0.5649 0.7098 0.3081 0.2620 1
Selumetinib C32 0.3160
uM
 48
hr
 1871 493 0.6705 0.7098 0.2635 0.2620 2
Selumetinib C32 0.3160
uM
 48
hr
 2091 510 0.7693 0.7098 0.2439 0.2620 3
Selumetinib C32 0.3160
uM
 48
hr
 2234 519 0.8345 0.7098 0.2323 0.2620 4
Selumetinib C32 0.3160
uM
 72
hr
 1164 545 0.2703 0.3472 0.4682 0.4026 1
Selumetinib C32 0.3160
uM
 72
hr
 1259 502 0.3305 0.3472 0.3987 0.4026 2
Selumetinib C32 0.3160
uM
 72
hr
 1466 562 0.3947 0.3472 0.3834 0.4026 3
Selumetinib C32 0.3160
uM
 72
hr
 1408 507 0.3934 0.3472 0.3601 0.4026 4
Selumetinib C32 1.0000
uM
 24
hr
 1918 470 0.8372 0.8612 0.2451 0.2365 1
Selumetinib C32 1.0000
uM
 24
hr
 2150 511 0.9476 0.8612 0.2377 0.2365 2
Selumetinib C32 1.0000
uM
 24
hr
 1833 410 0.8227 0.8612 0.2237 0.2365 3
Selumetinib C32 1.0000
uM
 24
hr
 1904 456 0.8372 0.8612 0.2395 0.2365 4
Selumetinib C32 1.0000
uM
 48
hr
 1375 847 0.2569 0.3220 0.6160 0.5982 1
Selumetinib C32 1.0000
uM
 48
hr
 1632 1017 0.2992 0.3220 0.6232 0.5982 2
Selumetinib C32 1.0000
uM
 48
hr
 1668 944 0.3523 0.3220 0.5660 0.5982 3
Selumetinib C32 1.0000
uM
 48
hr
 1891 1111 0.3795 0.3220 0.5875 0.5982 4
Selumetinib C32 1.0000
uM
 72
hr
 1001 816 0.0808 0.1124 0.8152 0.7591 1
Selumetinib C32 1.0000
uM
 72
hr
 1071 807 0.1153 0.1124 0.7535 0.7591 2
Selumetinib C32 1.0000
uM
 72
hr
 978 755 0.0974 0.1124 0.7720 0.7591 3
Selumetinib C32 1.0000
uM
 72
hr
 1176 818 0.1563 0.1124 0.6956 0.7591 4
Selumetinib C32 3.1600
uM
 24
hr
 1830 570 0.7285 0.8107 0.3115 0.2716 1