Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)

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Small Molecule Cell Line Drug Concentration Conc Unit Time Point Time Point Unit Total Number of Cells (Nuclei) Number of Apoptotic Cells Relative Viability Mean Relative Viability Apoptosis Fraction Mean Apoptosis Fraction Replicate
Selumetinib C32 0.0100
uM
 72
hr
 2817 218 1.1347 0.9982 0.0774 0.0822 4
Selumetinib C32 0.0316
uM
 24
hr
 1852 297 0.8990 1.0009 0.1604 0.1442 1
Selumetinib C32 0.0316
uM
 24
hr
 2224 308 1.1078 1.0009 0.1385 0.1442 2
Selumetinib C32 0.0316
uM
 24
hr
 1959 249 0.9887 1.0009 0.1271 0.1442 3
Selumetinib C32 0.0316
uM
 24
hr
 2054 310 1.0083 1.0009 0.1509 0.1442 4
Selumetinib C32 0.0316
uM
 48
hr
 2144 171 0.9600 1.1479 0.0798 0.0636 1
Selumetinib C32 0.0316
uM
 48
hr
 2432 161 1.1050 1.1479 0.0662 0.0636 2
Selumetinib C32 0.0316
uM
 48
hr
 2629 150 1.2062 1.1479 0.0571 0.0636 3
Selumetinib C32 0.0316
uM
 48
hr
 2861 147 1.3206 1.1479 0.0514 0.0636 4
Selumetinib C32 0.0316
uM
 72
hr
 2088 86 0.8741 0.9520 0.0412 0.0406 1
Selumetinib C32 0.0316
uM
 72
hr
 2047 83 0.8575 0.9520 0.0405 0.0406 2
Selumetinib C32 0.0316
uM
 72
hr
 2470 102 1.0339 0.9520 0.0413 0.0406 3
Selumetinib C32 0.0316
uM
 72
hr
 2486 98 1.0426 0.9520 0.0394 0.0406 4
Selumetinib C32 0.1000
uM
 24
hr
 1789 395 0.8060 0.8908 0.2208 0.2131 1
Selumetinib C32 0.1000
uM
 24
hr
 2033 467 0.9054 0.8908 0.2297 0.2131 2
Selumetinib C32 0.1000
uM
 24
hr
 1878 347 0.8852 0.8908 0.1848 0.2131 3
Selumetinib C32 0.1000
uM
 24
hr
 2136 464 0.9667 0.8908 0.2172 0.2131 4
Selumetinib C32 0.1000
uM
 48
hr
 2005 219 0.8690 0.9590 0.1092 0.1069 1
Selumetinib C32 0.1000
uM
 48
hr
 2200 249 0.9493 0.9590 0.1132 0.1069 2
Selumetinib C32 0.1000
uM
 48
hr
 2140 226 0.9313 0.9590 0.1056 0.1069 3
Selumetinib C32 0.1000
uM
 48
hr
 2480 247 1.0865 0.9590 0.0996 0.1069 4
Selumetinib C32 0.1000
uM
 72
hr
 1681 151 0.6680 0.6980 0.0898 0.1075 1
Selumetinib C32 0.1000
uM
 72
hr
 1825 176 0.7200 0.6980 0.0964 0.1075 2
Selumetinib C32 0.1000
uM
 72
hr
 1790 229 0.6815 0.6980 0.1279 0.1075 3
Selumetinib C32 0.1000
uM
 72
hr
 1872 217 0.7226 0.6980 0.1159 0.1075 4