Viability and apoptosis in BRAF(V600E/D) melanoma cell lines monitored by imaging - Dataset (ID:20217)
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| Small Molecule | Cell Line | Drug Concentration | Conc Unit | Time Point | Time Point Unit | Total Number of Cells (Nuclei) | Number of Apoptotic Cells | Relative Viability | Mean Relative Viability | Apoptosis Fraction | Mean Apoptosis Fraction | Replicate |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| AZ-628 | C32 | 3.1600 | uM | 72 | hr | 1035 | 958 | 0.0336 | 0.0269 | 0.9256 | 0.9414 | 3 |
| AZ-628 | C32 | 3.1600 | uM | 72 | hr | 1133 | 1071 | 0.0271 | 0.0269 | 0.9453 | 0.9414 | 4 |
| Selumetinib | C32 | 0.0032 | uM | 24 | hr | 1974 | 125 | 1.0690 | 1.0228 | 0.0633 | 0.0878 | 1 |
| Selumetinib | C32 | 0.0032 | uM | 24 | hr | 2271 | 188 | 1.2043 | 1.0228 | 0.0828 | 0.0878 | 2 |
| Selumetinib | C32 | 0.0032 | uM | 24 | hr | 1584 | 144 | 0.8326 | 1.0228 | 0.0909 | 0.0878 | 3 |
| Selumetinib | C32 | 0.0032 | uM | 24 | hr | 1924 | 220 | 0.9852 | 1.0228 | 0.1144 | 0.0878 | 4 |
| Selumetinib | C32 | 0.0032 | uM | 48 | hr | 2386 | 210 | 1.0588 | 1.2397 | 0.0880 | 0.0773 | 1 |
| Selumetinib | C32 | 0.0032 | uM | 48 | hr | 2620 | 197 | 1.1790 | 1.2397 | 0.0752 | 0.0773 | 2 |
| Selumetinib | C32 | 0.0032 | uM | 48 | hr | 2869 | 234 | 1.2821 | 1.2397 | 0.0816 | 0.0773 | 3 |
| Selumetinib | C32 | 0.0032 | uM | 48 | hr | 3161 | 204 | 1.4388 | 1.2397 | 0.0645 | 0.0773 | 4 |
| Selumetinib | C32 | 0.0032 | uM | 72 | hr | 1708 | 247 | 0.6379 | 0.8911 | 0.1446 | 0.1032 | 1 |
| Selumetinib | C32 | 0.0032 | uM | 72 | hr | 2216 | 206 | 0.8776 | 0.8911 | 0.0930 | 0.1032 | 2 |
| Selumetinib | C32 | 0.0032 | uM | 72 | hr | 2515 | 203 | 1.0094 | 0.8911 | 0.0807 | 0.1032 | 3 |
| Selumetinib | C32 | 0.0032 | uM | 72 | hr | 2629 | 248 | 1.0396 | 0.8911 | 0.0943 | 0.1032 | 4 |
| Selumetinib | C32 | 0.0100 | uM | 24 | hr | 1715 | 193 | 0.8800 | 1.0245 | 0.1125 | 0.1131 | 1 |
| Selumetinib | C32 | 0.0100 | uM | 24 | hr | 2015 | 239 | 1.0268 | 1.0245 | 0.1186 | 0.1131 | 2 |
| Selumetinib | C32 | 0.0100 | uM | 24 | hr | 2029 | 229 | 1.0407 | 1.0245 | 0.1129 | 0.1131 | 3 |
| Selumetinib | C32 | 0.0100 | uM | 24 | hr | 2232 | 242 | 1.1505 | 1.0245 | 0.1084 | 0.1131 | 4 |
| Selumetinib | C32 | 0.0100 | uM | 48 | hr | 1636 | 224 | 0.6870 | 1.0942 | 0.1369 | 0.0963 | 1 |
| Selumetinib | C32 | 0.0100 | uM | 48 | hr | 2376 | 197 | 1.0602 | 1.0942 | 0.0829 | 0.0963 | 2 |
| Selumetinib | C32 | 0.0100 | uM | 48 | hr | 2637 | 239 | 1.1668 | 1.0942 | 0.0906 | 0.0963 | 3 |
| Selumetinib | C32 | 0.0100 | uM | 48 | hr | 3249 | 243 | 1.4626 | 1.0942 | 0.0748 | 0.0963 | 4 |
| Selumetinib | C32 | 0.0100 | uM | 72 | hr | 2202 | 144 | 0.8985 | 0.9982 | 0.0654 | 0.0822 | 1 |
| Selumetinib | C32 | 0.0100 | uM | 72 | hr | 2393 | 196 | 0.9592 | 0.9982 | 0.0819 | 0.0822 | 2 |
| Selumetinib | C32 | 0.0100 | uM | 72 | hr | 2557 | 266 | 1.0003 | 0.9982 | 0.1040 | 0.0822 | 3 |