Basal profile of receptor tyrosine kinase signaling network measured by ELISA - Dataset (ID:20137)
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Cell Line | ERK (pg/cell) | Akt (pg/cell) | ErbB1 (pg/cell) | ErbB2 (pg/cell) | ErbB3 (pg/cell) | ErbB4 (pg/cell) | InsR (pg/cell) | IGF1R (pg/cell) | IGF2R (pg/cell) | VEGFR1 (pg/cell) | VEGFR2 (pg/cell) | VEGFR3 (pg/cell) | PDGFRa (pg/cell) | PDGFRb (pg/cell) | c-Met (pg/cell) | c-Kit (pg/cell) | EphA2 (pg/cell) | Src (pg/cell) | TrkA (pg/cell) | FGFR1 (pg/cell) | FGFR2 (pg/cell) | FGFR3 (pg/cell) | FGFR4 (pg/cell) | EpCAM (pg/cell) | pERK RnD (a.u.) | pERK CST (a.u.) | pAkt (a.u.) | pErbB1 (a.u.) | pErbB2 (a.u.) | pErbB3 (a.u.) | pErbB4 (a.u.) | pInsR (a.u.) | pIGF1R (a.u.) | pIGF1R (Y1131) (a.u.) | pVEGFR1 (a.u.) | pVEGFR2 (a.u.) | pVEGFR3 (a.u.) | pPDGFRa (a.u.) | pPDGFRb (a.u.) | pc-Met (a.u.) | pc-Kit (a.u.) | pEphA2 (a.u.) | pSrc (a.u.) | pTrkA (a.u.) | ER | PR |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Hs 578T | 0.001051 | 0.038658 | 0.108751 | 0.011487 | 0.000070 | 0.000015 | 0.000061 | 0.005070 | 0.021411 | 0.000007 | 0.000001 | 0.000193 | 0.032878 | 0.130946 | 0.205973 | 0.000000 | 0.081158 | 0.086798 | 0.000002 | 0.163343 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000027 | 0.000416 | 0.127930 | 0.007434 | 0.002229 | 0.000052 | 0.000027 | 0.036628 | 0.000037 | 0.010027 | 0.000037 | 0.000013 | 0.000080 | 0.004200 | 0.001565 | 0.000016 | 0.001249 | 0.000023 | 0.000076 | 0.000116 | 0.000006 | 0.000047 |
MCF7 | 0.001550 | 0.127939 | 0.011460 | 0.023167 | 0.039686 | 0.000015 | 0.006522 | 0.074180 | 0.021787 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.000084 | 0.000158 | 0.013895 | 0.123345 | 0.000002 | 0.262003 | 0.000002 | 0.000018 | 0.000001 | 0.707886 | 0.000027 | 0.000407 | 0.033586 | 0.000014 | 0.002229 | 0.000052 | 0.000027 | 0.043588 | 0.000037 | 0.193246 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000023 | 0.000116 | 0.003922 | 0.002145 |
AU565 | 0.000720 | 0.031863 | 0.058031 | 1.187170 | 0.029048 | 0.000015 | 0.005831 | 0.002778 | 0.022183 | 0.000130 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.077130 | 0.000000 | 0.006655 | 0.074540 | 0.000002 | 0.173121 | 0.000002 | 0.000018 | 0.000001 | 0.271855 | 0.000412 | 0.001843 | 0.273439 | 0.783490 | 1.082973 | 0.075842 | 0.018739 | 0.055730 | 0.011265 | 0.008868 | 0.000037 | 0.000013 | 0.001860 | 0.001745 | 0.000134 | 0.003091 | 0.001249 | 0.000152 | 0.000024 | 0.000116 | 0.000023 | 0.000066 |
SK-BR-3 | 0.001342 | 0.034698 | 0.048976 | 1.435347 | 0.020326 | 0.000015 | 0.006894 | 0.001849 | 0.022520 | 0.000393 | 0.000001 | 0.000193 | 0.000178 | 0.000148 | 0.012486 | 0.000000 | 0.007871 | 0.176013 | 0.000002 | 0.229318 | 0.001439 | 0.000018 | 0.000001 | 0.320775 | 0.000193 | 0.001075 | 0.260260 | 0.369062 | 1.193345 | 0.014139 | 0.050887 | 0.029773 | 0.004110 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.001633 | 0.000134 | 0.003998 | 0.001249 | 0.000023 | 0.000048 | 0.000116 | 0.000030 | 0.000125 |
184B5 | 0.000454 | 0.014484 | 0.199552 | 0.017611 | 0.002111 | 0.000015 | 0.001482 | 0.024421 | 0.024712 | 0.000108 | 0.001064 | 0.000193 | 0.000341 | 0.000006 | 0.421684 | 0.000000 | 0.022577 | 0.728929 | 0.000002 | 0.131405 | 0.000002 | 0.000018 | 0.000001 | 0.043860 | 0.000121 | 0.000989 | 0.064621 | 0.073694 | 0.004421 | 0.000052 | 0.001946 | 0.075541 | 0.018317 | 0.028019 | 0.000037 | 0.000013 | 0.000080 | 0.001258 | 0.000134 | 0.000879 | 0.001249 | 0.000023 | 0.000471 | 0.000430 | 0.000013 | 0.000061 |
MCF 10A | 0.000421 | 0.025576 | 0.132898 | 0.017434 | 0.001298 | 0.000015 | 0.000061 | 0.098369 | 0.025642 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.234945 | 0.000000 | 0.017445 | 0.342839 | 0.000002 | 0.157427 | 0.000002 | 0.000326 | 0.000001 | 0.009659 | 0.000027 | 0.000704 | 0.096342 | 0.020160 | 0.008104 | 0.000052 | 0.009461 | 0.034734 | 0.006760 | 0.035226 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000150 | 0.000116 | 0.000017 | 0.000054 |
UACC-812 | 0.002318 | 0.062712 | 0.003552 | 1.079578 | 0.011629 | 0.000015 | 0.000061 | 0.020988 | 0.030159 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.215155 | 0.000000 | 0.017181 | 1.395831 | 0.000002 | 0.292940 | 0.000132 | 0.000018 | 0.000001 | 0.268856 | 0.001274 | 0.006187 | 0.206463 | 0.016533 | 0.595025 | 0.000052 | 0.015995 | 0.000016 | 0.000037 | 0.109902 | 0.000037 | 0.000013 | 0.002079 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000628 | 0.000116 | 0.000341 | 0.000552 |
MDA-MB-231 | 0.000398 | 0.036028 | 0.083694 | 0.007956 | 0.000596 | 0.000015 | 0.000061 | 0.004737 | 0.031148 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.006061 | 0.080205 | 0.000000 | 0.117453 | 0.225337 | 0.000002 | 0.145332 | 0.000002 | 0.000018 | 0.000001 | 0.011123 | 0.000240 | 0.000712 | 0.006677 | 0.009967 | 0.003507 | 0.000052 | 0.001369 | 0.004480 | 0.000037 | 0.011474 | 0.000037 | 0.000013 | 0.000080 | 0.000578 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000116 | 0.000116 | 0.000025 | 0.000067 |
HCC1419 | 0.002537 | 0.068227 | 0.000084 | 3.032945 | 0.042585 | 0.000015 | 0.000061 | 0.005494 | 0.038255 | 0.000007 | 0.000001 | 0.000193 | 0.000178 | 0.000331 | 0.000084 | 0.000000 | 0.019854 | 0.013025 | 0.000002 | 0.182028 | 0.000002 | 0.000288 | 0.001468 | 0.337559 | 0.000627 | 0.004841 | 0.566139 | 0.086873 | 2.431691 | 0.157330 | 0.273441 | 0.089457 | 0.056446 | 0.001832 | 0.000037 | 0.001134 | 0.005877 | 0.013438 | 0.000134 | 0.005253 | 0.001249 | 0.001041 | 0.000012 | 0.001878 | 0.000192 | 0.000120 |
MDA-MB-436 | 0.000792 | 0.015135 | 0.029664 | 0.002771 | 0.000755 | 0.000015 | 0.000061 | 0.009875 | 0.043402 | 0.000434 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.261698 | 0.000000 | 0.074511 | 0.038248 | 0.000002 | 0.161437 | 0.000002 | 0.000018 | 0.000001 | 0.004527 | 0.000187 | 0.001376 | 0.289644 | 0.001623 | 0.002229 | 0.000052 | 0.000027 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.000009 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000041 | 0.000116 | 0.000006 | 0.000046 |
HCC1500 | 0.001627 | 0.030076 | 0.008530 | 0.028522 | 0.021393 | 0.000533 | 0.013918 | 0.024088 | 0.044645 | 0.000527 | 0.000001 | 0.000193 | 0.000178 | 0.000462 | 0.000084 | 0.000000 | 0.000026 | 0.394097 | 0.000002 | 0.206517 | 0.003372 | 0.000565 | 0.000309 | 0.125318 | 0.000242 | 0.000234 | 0.004047 | 0.007146 | 0.010088 | 0.000052 | 0.002743 | 0.035367 | 0.002356 | 0.038419 | 0.000037 | 0.000013 | 0.000080 | 0.001452 | 0.000134 | 0.009774 | 0.001249 | 0.000023 | 0.000149 | 0.000895 | 0.004777 | 0.001929 |
HCC1187 | 0.001231 | 0.067625 | 0.078729 | 0.041583 | 0.003479 | 0.000015 | 0.011093 | 0.000584 | 0.052908 | 0.000770 | 0.001859 | 0.000193 | 0.000393 | 0.000289 | 0.000084 | 0.018901 | 0.003747 | 0.287014 | 0.000002 | 0.279688 | 0.000459 | 0.000018 | 0.000001 | 0.158536 | 0.000156 | 0.000638 | 0.249109 | 0.010311 | 0.015487 | 0.000052 | 0.001503 | 0.000016 | 0.000037 | 0.001832 | 0.000037 | 0.011705 | 0.000080 | 0.001174 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000065 | 0.000116 | 0.000059 | 0.000147 |
UACC-893 | 0.001192 | 0.071233 | 0.055166 | 3.442462 | 0.021268 | 0.000015 | 0.004520 | 0.000206 | 0.062033 | 0.002080 | 0.000001 | 0.000193 | 0.000178 | 0.000006 | 0.023068 | 0.000000 | 0.010849 | 0.069885 | 0.000431 | 0.082970 | 0.004376 | 0.008224 | 0.002049 | 0.948209 | 0.001689 | 0.003509 | 1.943655 | 0.193576 | 2.123039 | 0.040024 | 0.041467 | 0.049085 | 0.021447 | 0.001832 | 0.000037 | 0.000013 | 0.001774 | 0.007064 | 0.000134 | 0.005683 | 0.001249 | 0.000023 | 0.000079 | 0.002605 | 0.000177 | 0.000433 |
BT-549 | 0.001734 | 0.028424 | 0.139275 | 0.011181 | 0.000070 | 0.000015 | 0.000061 | 0.005810 | 0.076807 | 0.000499 | 0.000001 | 0.000193 | 0.000497 | 0.000150 | 0.302179 | 0.000000 | 0.286646 | 0.294228 | 0.000002 | 0.294733 | 0.000002 | 0.000018 | 0.000001 | 0.000084 | 0.000476 | 0.002044 | 0.303062 | 0.016341 | 0.012222 | 0.000052 | 0.014529 | 0.007478 | 0.005798 | 0.001832 | 0.000037 | 0.000013 | 0.000080 | 0.004543 | 0.000134 | 0.000016 | 0.001249 | 0.000023 | 0.000203 | 0.000116 | 0.000041 | 0.000118 |