Metrics other than potency reveal systematic variation in responses to cancer drugs - Dataset (ID:20120)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | Cell Line | log10[max. dose (M)] | R^2 (goodness of fit) | log10[EC50 (M)] | log10[IC50 (M)] | log10[GI50 (M)] | HillSlope | E_inf | E_max | AUC |
|---|---|---|---|---|---|---|---|---|---|---|
| Vinorelbine | HCC202 | -4.3335 | 0.8707 | -5.7985 | -5.7988 | NaN | 0.3858 | 0.0000 | 0.2139 | 6.1447 |
| Vinorelbine | HCC38 | -4.3335 | 0.9214 | -7.7570 | -7.6518 | -7.9162 | 2.5860 | 0.1921 | 0.1922 | 4.5617 |
| Vinorelbine | HCC1954 | -4.3335 | 0.8463 | -8.2095 | -8.1427 | -8.3181 | 2.9650 | 0.1842 | 0.1842 | 3.8895 |
| Vinorelbine | HCC70 | -4.3335 | 0.8579 | -7.6870 | -7.5722 | -7.7966 | 2.8670 | 0.2475 | 0.2475 | 4.9618 |
| Vinorelbine | HCC1569 | -4.3335 | 0.8898 | -6.3490 | -6.3490 | -6.3653 | 0.4765 | 0.0000 | 0.1190 | 5.7630 |
| Vinorelbine | HCC1806 | -4.3335 | 0.9910 | -8.2425 | -8.2240 | -8.2912 | 3.8810 | 0.0763 | 0.0763 | 3.3665 |
| Vinorelbine | Hs 578T | -4.3335 | 0.9828 | -8.4295 | -8.3827 | -8.6943 | 2.6070 | 0.0730 | 0.0730 | 3.0790 |
| Vinorelbine | HCC1937 | -4.3335 | 0.7866 | -5.7920 | -5.7917 | NaN | 0.3574 | 0.0000 | 0.2341 | 6.3165 |
| Vinorelbine | HCC1395 | -4.3335 | 0.9719 | -8.1050 | -8.0457 | -8.3061 | 2.4500 | 0.1351 | 0.1351 | 3.8075 |
| Vinorelbine | HCC1419 | -4.3335 | 0.7958 | -5.3196 | -5.3194 | -7.0980 | 0.4106 | 0.0000 | 0.2709 | 6.4006 |
| Vinorelbine | SUM149PT | -4.3335 | 0.9420 | -7.8895 | -7.8406 | -7.8780 | 3.9990 | 0.1822 | 0.1822 | 4.4555 |
| Vinorelbine | CAMA-1 | -4.3335 | 0.8546 | -7.8915 | -7.7976 | -7.9419 | 3.9990 | 0.2885 | 0.2885 | 5.0736 |
| Vinorelbine | HCC1143 | -4.3335 | 0.7251 | -7.5695 | -7.3296 | -7.5171 | 3.9960 | 0.4451 | 0.4451 | 6.2724 |
| Vinorelbine | HCC1428 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Vinorelbine | MB 157 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |
| Valproic acid | AU565 | -1.8239 | 0.9633 | -2.7437 | -2.7436 | -2.8960 | 1.9410 | 0.0000 | 0.0161 | 7.1314 |
| Valproic acid | BT-20 | -1.8239 | 0.8160 | -2.3127 | -2.0752 | -2.4689 | 3.2920 | 0.2469 | 0.2785 | 7.8380 |
| Valproic acid | BT-474 | -1.8239 | 0.9366 | -2.5820 | -2.5821 | -3.1409 | 1.3030 | 0.0000 | 0.1051 | 7.1024 |
| Valproic acid | BT-483 | -1.8239 | 0.9401 | -2.3275 | -2.3276 | -3.1245 | 1.1890 | 0.0000 | 0.2015 | 7.4905 |
| Valproic acid | 600MPE | -1.8239 | 0.9019 | -2.1659 | -1.8239 | -2.5107 | 0.9830 | 0.3008 | 0.5215 | 8.0931 |
| Valproic acid | HCC2185 | -1.8239 | 0.9298 | -2.4412 | -2.4374 | -2.9673 | 2.8680 | 0.0170 | 0.0587 | 7.6315 |
| Valproic acid | T47DKBLUC | -1.8239 | 0.9707 | -2.4693 | -2.4694 | -2.7858 | 1.6510 | 0.0000 | 0.0792 | 7.4323 |
| Valproic acid | HCC3153 | -1.8239 | 0.9730 | -2.4393 | -2.4161 | -2.5695 | 3.0895 | 0.0747 | 0.1010 | 7.7687 |
| Valproic acid | MX1 | -1.8239 | 0.9515 | -2.9369 | -2.9367 | -3.4290 | 1.4100 | 0.0000 | 0.0266 | 6.5536 |
| Valproic acid | LY2 | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN | NaN |