XMD-12 KiNativ -- single dose experiment - Dataset (ID:20103)
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| Small Molecule | Cell Line | Protein | Sequence | Labeling Site | % Inhibition | Assay compound conc | Conc unit |
|---|---|---|---|---|---|---|---|
| XMD-12 | PC-3 | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIkGQNVLLTENAEVK | Lys2 | -7.1 | 10 | uM |
| XMD-12 | HeLa | ZC1/HGK,ZC2/TNIK,ZC3/MINK | DIkGQNVLLTENAEVK | Lys2 | 22.4 | 10 | uM |
| XMD-12 | PC-3 | WNK4 | DLkCDNVFITGPTGSVK | Lys2 | -10.1 | 10 | uM |
| XMD-12 | PC-3 | Wnk1,Wnk2,Wnk4 | IGDLGLATLkR | Activation Loop | -11.9 | 10 | uM |
| XMD-12 | HeLa | Wnk1,Wnk2,Wnk3 | DLkCDNIFITGPTGSVK | Lys2 | 2.8 | 10 | uM |
| XMD-12 | HeLa | WEE1 | YIHSMSLVHMDIkPSNIFISR | Lys2 | 10 | uM | |
| XMD-12 | HeLa | ULK3 | EVVAIkCVAK | Lys1 | 34.2 | 10 | uM |
| XMD-12 | HeLa | ULK1 | DLkPQNILLSNPAGR | Lys2 | -9.3 | 10 | uM |
| XMD-12 | PC-3 | TLK2 | YVAVkIHQLNK | Lys1 | -11.7 | 10 | uM |
| XMD-12 | PC-3 | TLK1 | YLNEIKPPIIHYDLkPGNILLVDGTACGEIK | Lys2 | -7.5 | 10 | uM |
| XMD-12 | PC-3 | TLK1 | YAAVkIHQLNK | Lys1 | -47.5 | 10 | uM |
| XMD-12 | HeLa | TLK1 | YLNEIKPPIIHYDLkPGNILLVDGTACGEIK | Lys2 | -20.1 | 10 | uM |
| XMD-12 | HeLa | TLK1 | YAAVkIHQLNK | Lys1 | -23.8 | 10 | uM |
| XMD-12 | HeLa | TEC | YVLDDQYTSSSGAkFPVK | Activation Loop | 11.2 | 10 | uM |
| XMD-12 | HeLa | TBK1 | TGDLFAIkVFNNISFLRPVDVQMR | Lys1 | 10 | uM | |
| XMD-12 | PC-3 | TAOK2 | DVkAGNILLSEPGLVK | Lys2 | 91.3 | 10 | uM |
| XMD-12 | PC-3 | TAO1,TAOK3 | DIkAGNILLTEPGQVK | Lys2 | 52.3 | 10 | uM |
| XMD-12 | HeLa | TAO1,TAOK3 | DIkAGNILLTEPGQVK | Lys2 | 28.9 | 10 | uM |
| XMD-12 | HeLa | SYK | ISDFGLSkALR | Activation Loop | 2.1 | 10 | uM |
| XMD-12 | HeLa | STLK5 | YSVkVLPWLSPEVLQQNLQGYDAK | Activation Loop | 10 | uM | |
| XMD-12 | PC-3 | SRPK1/2 | FVAMkVVK | Lys1 | 44.7 | 10 | uM |
| XMD-12 | PC-3 | SRPK1 | IIHTDIkPENILLSVNEQYIR | Lys2 | 22.2 | 10 | uM |
| XMD-12 | PC-3 | SRC | VAIkTLKPGTMSPEAFLQEAQVMK | Lys1 | 94.6 | 10 | uM |
| XMD-12 | PC-3 | SNRK | DLkPENVVFFEK | Lys2 | -15.0 | 10 | uM |
| XMD-12 | HeLa | SMG1 | DTVTIHSVGGTITILPTkTKPK | ATP | -5.5 | 10 | uM |