LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Palbociclib | 180703_BG_10 | 10293 | 0.0152 | 46 | 111 | 9 | 18 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_3 | 157 | 0.0150 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01678 | 0.6591 |
| Trametinib | 180703_BG_10 | 18245 | 0.0155 | 45 | 238 | 9 | 20 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_1 | 283 | 0.0153 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01652 | 0.9173 |
| Palbociclib | 180703_BG_11 | 14781 | 0.0155 | 81 | 149 | 12 | 16 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_6 | 230 | 0.0153 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01648 | 0.8179 |
| Palbociclib | 180703_BG_11 | 12185 | 0.0155 | 81 | 109 | 10 | 12 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_4 | 190 | 0.0154 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01645 | 0.7314 |
| Neratinib | 180703_BG_10 | 15469 | 0.0156 | 59 | 184 | 14 | 15 | Neratinib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_2 | 243 | 0.0155 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01633 | 0.8390 |
| Palbociclib | 180703_BG_12 | 8077 | 0.0156 | 40 | 87 | 4 | 13 | Palbociclib | 3.160329361 | treatment | 72 | 3 | MCF10A-GM_7 | 127 | 0.0155 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01632 | 0.5605 |
| Dasatinib | 180703_BG_10 | 20280 | 0.0158 | 43 | 278 | 10 | 17 | Dasatinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 321 | 0.0156 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01622 | 0.9692 |
| Alpelisib | 180703_BG_12 | 13199 | 0.0158 | 49 | 160 | 4 | 12 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_7 | 209 | 0.0156 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01621 | 0.7667 |
| Palbociclib | 180703_BG_10 | 5152 | 0.0158 | 37 | 45 | 11 | 4 | Palbociclib | 3.160329361 | treatment | 72 | 3 | MCF10A-GM_3 | 82 | 0.0157 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01613 | 0.3929 |
| Neratinib | 180703_BG_10 | 5840 | 0.0159 | 22 | 71 | 10 | 8 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_2 | 93 | 0.0157 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01612 | 0.4378 |
| Alpelisib | 180703_BG_10 | 19788 | 0.0159 | 33 | 283 | 10 | 18 | Alpelisib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_3 | 316 | 0.0157 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01608 | 0.9570 |
| Palbociclib | 180703_BG_10 | 7516 | 0.0160 | 55 | 66 | 3 | 11 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_1 | 121 | 0.0158 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01596 | 0.5324 |
| Neratinib | 180703_BG_12 | 14180 | 0.0161 | 69 | 160 | 9 | 16 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_9 | 229 | 0.0159 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01591 | 0.7990 |
| Alpelisib | 180703_BG_12 | 12063 | 0.0162 | 30 | 166 | 10 | 10 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_8 | 196 | 0.0160 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01581 | 0.7270 |
| Alpelisib | 180703_BG_12 | 17630 | 0.0163 | 44 | 244 | 6 | 12 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_8 | 288 | 0.0161 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01573 | 0.9007 |
| Palbociclib | 180703_BG_12 | 11405 | 0.0165 | 55 | 134 | 6 | 14 | Palbociclib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_7 | 189 | 0.0163 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01550 | 0.7027 |
| Palbociclib | 180703_BG_10 | 14219 | 0.0165 | 51 | 185 | 5 | 12 | Palbociclib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_1 | 236 | 0.0163 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01547 | 0.8002 |
| Trametinib | 180703_BG_10 | 14962 | 0.0166 | 56 | 194 | 14 | 21 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_3 | 250 | 0.0164 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01536 | 0.8235 |
| Palbociclib | 180703_BG_10 | 7291 | 0.0166 | 52 | 70 | 9 | 15 | Palbociclib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_2 | 122 | 0.0165 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01534 | 0.5207 |
| Alpelisib | 180703_BG_10 | 11828 | 0.0168 | 39 | 160 | 10 | 5 | Alpelisib | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_3 | 199 | 0.0165 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01525 | 0.7184 |
| Palbociclib | 180703_BG_12 | 8582 | 0.0168 | 55 | 90 | 9 | 18 | Palbociclib | 3.160329361 | treatment | 72 | 3 | MCF10A-GM_8 | 145 | 0.0166 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01518 | 0.5846 |
| Neratinib | 180703_BG_10 | 20112 | 0.0170 | 57 | 285 | 6 | 12 | Neratinib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_2 | 342 | 0.0167 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01508 | 0.9651 |
| Etoposide | 180703_BG_12 | 15839 | 0.0172 | 63 | 211 | 11 | 17 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_9 | 274 | 0.0170 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01479 | 0.8500 |
| Dasatinib | 180703_BG_10 | 11456 | 0.0173 | 42 | 157 | 6 | 16 | Dasatinib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_3 | 199 | 0.0171 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01472 | 0.7046 |
| Alpelisib | 180703_BG_10 | 14480 | 0.0173 | 76 | 176 | 6 | 5 | Alpelisib | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_2 | 252 | 0.0171 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01469 | 0.8085 |