LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180614_BG_03 | 16626 | 0.0137 | 59 | 170 | 14 | 11 | Neratinib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_6 | 229 | 0.0136 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00641 | 0.9881 |
| Neratinib | 180622_BG_7 | 13618 | 0.0200 | 73 | 201 | 8 | 6 | Neratinib | 0.099799997 | treatment | 72 | 2 | MCF10A-GM_5 | 274 | 0.0197 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00640 | 0.8390 |
| Etoposide | 180703_BG_11 | 19596 | 0.0259 | 102 | 409 | 12 | 7 | Etoposide | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_5 | 511 | 0.0254 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00639 | 0.9522 |
| Dasatinib | 180703_BG_10 | 11350 | 0.0259 | 78 | 218 | 6 | 6 | Dasatinib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_2 | 296 | 0.0254 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00638 | 0.7006 |
| Alpelisib | 180622_BG_7 | 11880 | 0.0201 | 58 | 182 | 11 | 21 | Alpelisib | 3.193598006 | treatment | 72 | 2 | MCF10A-GM_6 | 240 | 0.0198 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00632 | 0.7851 |
| Alpelisib | 180703_BG_10 | 20811 | 0.0261 | 54 | 490 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_3 | 544 | 0.0255 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00632 | 0.9821 |
| Palbociclib | 180622_BG_6 | 15166 | 0.0201 | 77 | 230 | 14 | 11 | Palbociclib | 0.099799997 | treatment | 72 | 2 | MCF10A-GM_3 | 307 | 0.0198 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00628 | 0.8826 |
| Palbociclib | 180622_BG_7 | 17831 | 0.0202 | 50 | 311 | 13 | 10 | Palbociclib | 0.00998 | treatment | 72 | 2 | MCF10A-GM_5 | 361 | 0.0198 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00628 | 0.9502 |
| Taxol | 180703_BG_10 | 20272 | 0.0261 | 78 | 453 | 14 | 5 | Paclitaxel | 0.000998 | treatment | 72 | 3 | MCF10A-GM_3 | 531 | 0.0255 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00627 | 0.9690 |
| Palbociclib | 180622_BG_6 | 9659 | 0.0201 | 90 | 106 | 5 | 12 | Palbociclib | 0.099799997 | treatment | 72 | 2 | MCF10A-GM_1 | 196 | 0.0199 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00624 | 0.7063 |
| Etoposide | 180622_BG_7 | 19564 | 0.0203 | 35 | 362 | 10 | 20 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_5 | 397 | 0.0199 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00624 | 0.9901 |
| Taxol | 180703_BG_10 | 21215 | 0.0262 | 71 | 486 | 13 | 7 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_3 | 557 | 0.0256 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00622 | 0.9918 |
| Trametinib | 180703_BG_12 | 19386 | 0.0261 | 96 | 413 | 7 | 11 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_8 | 509 | 0.0256 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00621 | 0.9469 |
| Palbociclib | 180703_BG_11 | 11433 | 0.0260 | 165 | 136 | 11 | 5 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_5 | 301 | 0.0257 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00615 | 0.7037 |
| Taxol | 180622_BG_7 | 19664 | 0.0204 | 31 | 370 | 13 | 17 | Paclitaxel | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_6 | 401 | 0.0200 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00614 | 0.9923 |
| Alpelisib | 180622_BG_6 | 14801 | 0.0203 | 94 | 208 | 12 | 11 | Alpelisib | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_3 | 302 | 0.0200 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00613 | 0.8727 |
| Palbociclib | 180622_BG_7 | 9756 | 0.0204 | 69 | 131 | 11 | 5 | Palbociclib | 0.332666627 | treatment | 72 | 2 | MCF10A-GM_5 | 200 | 0.0201 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00604 | 0.7101 |
| Palbociclib | 180622_BG_8 | 8441 | 0.0204 | 49 | 124 | 3 | 6 | Palbociclib | 0.332666627 | treatment | 72 | 2 | MCF10A-GM_7 | 173 | 0.0201 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00604 | 0.6569 |
| Palbociclib | 180703_BG_12 | 18751 | 0.0264 | 71 | 425 | 4 | 19 | Palbociclib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_7 | 496 | 0.0258 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00603 | 0.9306 |
| Palbociclib | 180703_BG_11 | 7551 | 0.0261 | 122 | 78 | 10 | 16 | Palbociclib | 3.160329361 | treatment | 72 | 3 | MCF10A-GM_5 | 200 | 0.0258 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00600 | 0.5342 |
| Trametinib | 180622_BG_7 | 13214 | 0.0204 | 90 | 182 | 7 | 15 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_5 | 272 | 0.0202 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00596 | 0.8269 |
| Etoposide | 180622_BG_8 | 20215 | 0.0205 | 39 | 377 | 12 | 17 | Etoposide | 0.00998 | treatment | 72 | 2 | MCF10A-GM_9 | 416 | 0.0202 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00596 | 1.0043 |
| Alpelisib | 180622_BG_6 | 18176 | 0.0205 | 52 | 322 | 10 | 18 | Alpelisib | 0.099799999 | treatment | 72 | 2 | MCF10A-GM_3 | 374 | 0.0202 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00596 | 0.9584 |
| Alpelisib | 180622_BG_7 | 19392 | 0.0205 | 36 | 363 | 10 | 21 | Alpelisib | 0.00998 | treatment | 72 | 2 | MCF10A-GM_5 | 399 | 0.0202 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00596 | 0.9862 |
| Etoposide | 180703_BG_12 | 9420 | 0.0263 | 75 | 175 | 6 | 22 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_7 | 250 | 0.0259 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00595 | 0.6224 |