LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180622_BG_8 | 21170 | 0.0268 | 56 | 513 | 11 | 22 | Neratinib | 0.001081167 | treatment | 72 | 2 | MCF10A-GM_8 | 569 | 0.0262 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.00005 | 1.0246 |
| Vorinostat | 180703_BG_10 | 22679 | 0.0345 | 62 | 723 | 5 | 13 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 785 | 0.0335 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00166 | 1.0256 |
| Taxol | 180614_BG_04 | 18063 | 0.0199 | 70 | 290 | 9 | 20 | Paclitaxel | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_7 | 360 | 0.0195 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00045 | 1.0272 |
| Etoposide | 180622_BG_8 | 21315 | 0.0229 | 52 | 438 | 11 | 4 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_7 | 490 | 0.0225 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00365 | 1.0276 |
| Neratinib | 180622_BG_8 | 21382 | 0.0280 | 44 | 556 | 9 | 12 | Neratinib | 0.00998 | treatment | 72 | 2 | MCF10A-GM_8 | 600 | 0.0273 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.00117 | 1.0290 |
| Neratinib | 180614_BG_02 | 18291 | 0.0179 | 24 | 304 | 9 | 8 | Neratinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 328 | 0.0176 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00238 | 1.0331 |