LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vorinostat | 180614_BG_03 | 8633 | 0.0191 | 71 | 95 | 12 | 17 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_5 | 166 | 0.0189 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00113 | 0.7047 |
| Etoposide | 180622_BG_8 | 18660 | 0.0192 | 40 | 319 | 9 | 14 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_9 | 359 | 0.0189 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00725 | 0.9696 |
| Neratinib | 180614_BG_02 | 17844 | 0.0193 | 43 | 303 | 6 | 9 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 346 | 0.0190 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00097 | 1.0214 |
| Alpelisib | 180614_BG_04 | 16458 | 0.0192 | 110 | 208 | 9 | 15 | Alpelisib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_9 | 318 | 0.0190 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00104 | 0.9834 |
| Palbociclib | 180614_BG_04 | 17013 | 0.0193 | 99 | 231 | 12 | 6 | Palbociclib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_8 | 330 | 0.0190 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00097 | 0.9989 |
| Palbociclib | 180614_BG_02 | 7434 | 0.0193 | 45 | 99 | 5 | 12 | Palbociclib | 0.099799997 | treatment | 72 | 1 | MCF10A-GM_1 | 144 | 0.0190 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00099 | 0.6460 |
| Etoposide | 180622_BG_6 | 11688 | 0.0192 | 82 | 144 | 14 | 17 | Etoposide | 0.099799999 | treatment | 72 | 2 | MCF10A-GM_3 | 226 | 0.0190 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00716 | 0.7787 |
| Etoposide | 180622_BG_7 | 17257 | 0.0193 | 66 | 269 | 12 | 7 | Etoposide | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_5 | 335 | 0.0190 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00708 | 0.9364 |
| Trametinib | 180614_BG_02 | 16814 | 0.0194 | 28 | 298 | 9 | 20 | Trametinib | 0.000332667 | treatment | 72 | 1 | MCF10A-GM_1 | 326 | 0.0190 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00098 | 0.9934 |
| Etoposide | 180614_BG_04 | 15294 | 0.0192 | 118 | 178 | 9 | 14 | Etoposide | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_9 | 296 | 0.0190 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00101 | 0.9495 |
| Dasatinib | 180614_BG_02 | 16726 | 0.0193 | 62 | 262 | 12 | 9 | Dasatinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_2 | 324 | 0.0190 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00099 | 0.9909 |
| Etoposide | 180622_BG_7 | 19471 | 0.0193 | 45 | 332 | 12 | 18 | Etoposide | 0.003326667 | treatment | 72 | 2 | MCF10A-GM_6 | 377 | 0.0190 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00713 | 0.9880 |
| Alpelisib | 180622_BG_7 | 19041 | 0.0193 | 56 | 312 | 9 | 4 | Alpelisib | 0.099799999 | treatment | 72 | 2 | MCF10A-GM_5 | 368 | 0.0190 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00716 | 0.9783 |
| Neratinib | 180614_BG_03 | 17086 | 0.0194 | 58 | 275 | 14 | 14 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_6 | 333 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00088 | 1.0009 |
| Dasatinib | 180622_BG_7 | 16614 | 0.0194 | 57 | 267 | 8 | 18 | Dasatinib | 0.033266667 | treatment | 72 | 2 | MCF10A-GM_6 | 324 | 0.0191 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00700 | 0.9204 |
| Neratinib | 180614_BG_02 | 16951 | 0.0194 | 39 | 291 | 14 | 20 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 330 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00090 | 0.9972 |
| Alpelisib | 180614_BG_02 | 16888 | 0.0194 | 31 | 298 | 9 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_2 | 329 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00089 | 0.9954 |
| Alpelisib | 180614_BG_02 | 15804 | 0.0194 | 71 | 237 | 3 | 7 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_1 | 308 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00088 | 0.9646 |
| Alpelisib | 180703_BG_12 | 18572 | 0.0194 | 66 | 296 | 12 | 22 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_9 | 362 | 0.0191 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01268 | 0.9259 |
| Palbociclib | 180703_BG_12 | 10672 | 0.0193 | 78 | 130 | 3 | 6 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_7 | 208 | 0.0191 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01268 | 0.6743 |
| Etoposide | 180614_BG_04 | 10452 | 0.0192 | 99 | 104 | 3 | 22 | Etoposide | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_7 | 203 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00094 | 0.7829 |
| Vorinostat | 180703_BG_10 | 12049 | 0.0194 | 52 | 183 | 8 | 8 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_3 | 235 | 0.0191 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01267 | 0.7265 |
| Trametinib | 180703_BG_12 | 3489 | 0.0192 | 47 | 21 | 10 | 5 | Trametinib | 0.031603332 | treatment | 72 | 3 | MCF10A-GM_8 | 68 | 0.0191 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01268 | 0.2623 |
| Etoposide | 180614_BG_02 | 17281 | 0.0194 | 48 | 289 | 9 | 5 | Etoposide | 0.00998 | treatment | 72 | 1 | MCF10A-GM_1 | 337 | 0.0191 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00087 | 1.0062 |
| Neratinib | 180614_BG_04 | 17963 | 0.0194 | 90 | 261 | 5 | 5 | Neratinib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 351 | 0.0192 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00083 | 1.0245 |