LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Etoposide | 180703_BG_12 | 9932 | 0.0144 | 30 | 113 | 10 | 11 | Etoposide | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_9 | 143 | 0.0142 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01761 | 0.6442 |
| Alpelisib | 180614_BG_03 | 15607 | 0.0144 | 44 | 182 | 12 | 21 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_6 | 226 | 0.0143 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00572 | 0.9588 |
| Trametinib | 180703_BG_12 | 16500 | 0.0145 | 44 | 196 | 12 | 14 | Trametinib | 0.000998 | treatment | 72 | 3 | MCF10A-GM_9 | 240 | 0.0143 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01746 | 0.8692 |
| Dasatinib | 180703_BG_12 | 15475 | 0.0145 | 60 | 166 | 12 | 8 | Dasatinib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_9 | 226 | 0.0144 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01741 | 0.8391 |
| Alpelisib | 180703_BG_10 | 16726 | 0.0145 | 42 | 201 | 5 | 20 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_1 | 243 | 0.0143 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01748 | 0.8756 |
| Trametinib | 180703_BG_12 | 10087 | 0.0145 | 35 | 112 | 10 | 9 | Trametinib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 147 | 0.0144 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01744 | 0.6506 |
| Alpelisib | 180614_BG_02 | 15928 | 0.0147 | 16 | 219 | 10 | 18 | Alpelisib | 0.099799999 | treatment | 72 | 1 | MCF10A-GM_3 | 235 | 0.0145 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00546 | 0.9682 |
| Vorinostat | 180614_BG_03 | 17008 | 0.0147 | 23 | 228 | 9 | 21 | Vorinostat | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_6 | 251 | 0.0145 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00545 | 0.9987 |
| Alpelisib | 180703_BG_10 | 17588 | 0.0147 | 40 | 219 | 12 | 6 | Alpelisib | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_3 | 259 | 0.0145 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01729 | 0.8996 |
| Palbociclib | 180703_BG_10 | 16274 | 0.0147 | 40 | 200 | 11 | 15 | Palbociclib | 0.031603333 | treatment | 72 | 3 | MCF10A-GM_3 | 240 | 0.0145 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01727 | 0.8627 |
| Dasatinib | 180614_BG_02 | 13937 | 0.0147 | 40 | 166 | 8 | 21 | Dasatinib | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_1 | 206 | 0.0146 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00543 | 0.9075 |
| Palbociclib | 180614_BG_03 | 16827 | 0.0148 | 39 | 211 | 12 | 14 | Palbociclib | 0.001081167 | treatment | 72 | 1 | MCF10A-GM_5 | 250 | 0.0146 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00536 | 0.9937 |
| Neratinib | 180703_BG_12 | 14764 | 0.0149 | 46 | 174 | 4 | 6 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_7 | 220 | 0.0147 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01712 | 0.8174 |
| Etoposide | 180614_BG_03 | 16603 | 0.0149 | 22 | 225 | 10 | 20 | Etoposide | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_5 | 247 | 0.0147 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00534 | 0.9875 |
| Etoposide | 180614_BG_03 | 14228 | 0.0150 | 49 | 165 | 12 | 7 | Etoposide | 0.033266667 | treatment | 72 | 1 | MCF10A-GM_5 | 214 | 0.0148 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00518 | 0.9168 |
| Palbociclib | 180614_BG_02 | 13226 | 0.0150 | 24 | 175 | 11 | 15 | Palbociclib | 0.031603333 | treatment | 72 | 1 | MCF10A-GM_3 | 199 | 0.0148 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00517 | 0.8842 |
| Alpelisib | 180614_BG_04 | 16866 | 0.0150 | 64 | 190 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_7 | 254 | 0.0148 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00516 | 0.9948 |
| Alpelisib | 180614_BG_03 | 16550 | 0.0151 | 53 | 198 | 10 | 21 | Alpelisib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_5 | 251 | 0.0149 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00506 | 0.9860 |
| Palbociclib | 180703_BG_10 | 14713 | 0.0151 | 35 | 187 | 14 | 11 | Palbociclib | 0.099799997 | treatment | 72 | 3 | MCF10A-GM_3 | 222 | 0.0149 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01693 | 0.8158 |
| Alpelisib | 180622_BG_8 | 8502 | 0.0151 | 31 | 98 | 9 | 22 | Alpelisib | 9.98 | treatment | 72 | 2 | MCF10A-GM_7 | 129 | 0.0149 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.01118 | 0.6595 |
| Palbociclib | 180703_BG_10 | 10293 | 0.0152 | 46 | 111 | 9 | 18 | Palbociclib | 0.332666627 | treatment | 72 | 3 | MCF10A-GM_3 | 157 | 0.0150 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01678 | 0.6591 |
| Trametinib | 180614_BG_02 | 6020 | 0.0152 | 23 | 69 | 12 | 21 | Trametinib | 0.003326667 | treatment | 72 | 1 | MCF10A-GM_2 | 92 | 0.0151 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00494 | 0.5665 |
| Alpelisib | 180703_BG_10 | 8407 | 0.0152 | 39 | 89 | 8 | 17 | Alpelisib | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 128 | 0.0150 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01680 | 0.5764 |
| Dasatinib | 180703_BG_10 | 17271 | 0.0152 | 49 | 214 | 11 | 16 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_2 | 263 | 0.0150 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01680 | 0.8909 |
| Etoposide | 180622_BG_7 | 12621 | 0.0152 | 40 | 153 | 11 | 20 | Etoposide | 0.099799999 | treatment | 72 | 2 | MCF10A-GM_6 | 193 | 0.0151 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.01106 | 0.8088 |