LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Neratinib | 180703_BG_10 | 5840 | 0.0159 | 22 | 71 | 10 | 8 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_2 | 93 | 0.0157 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01612 | 0.4378 |
| Neratinib | 180703_BG_10 | 6644 | 0.0190 | 42 | 85 | 11 | 19 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_3 | 127 | 0.0188 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01304 | 0.4854 |
| Neratinib | 180703_BG_11 | 10746 | 0.0276 | 142 | 159 | 9 | 16 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_5 | 301 | 0.0272 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00455 | 0.6773 |
| Neratinib | 180703_BG_11 | 11213 | 0.0214 | 121 | 122 | 14 | 9 | Neratinib | 0.299399965 | treatment | 72 | 3 | MCF10A-GM_6 | 243 | 0.0212 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01059 | 0.6954 |
| Alpelisib | 180703_BG_10 | 21555 | 0.0242 | 61 | 463 | 7 | 14 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 524 | 0.0237 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00807 | 0.9998 |
| Alpelisib | 180703_BG_10 | 21511 | 0.0279 | 49 | 552 | 8 | 11 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_2 | 601 | 0.0272 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00462 | 0.9987 |
| Alpelisib | 180703_BG_11 | 21795 | 0.0345 | 187 | 572 | 3 | 13 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_4 | 759 | 0.0337 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00185 | 1.0054 |
| Alpelisib | 180703_BG_11 | 21507 | 0.0339 | 123 | 611 | 8 | 17 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_5 | 734 | 0.0330 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00120 | 0.9986 |
| Alpelisib | 180703_BG_12 | 21706 | 0.0371 | 74 | 734 | 11 | 6 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 808 | 0.0359 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00409 | 1.0033 |
| Alpelisib | 180703_BG_12 | 21437 | 0.0315 | 58 | 619 | 13 | 22 | Alpelisib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_9 | 677 | 0.0306 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00119 | 0.9970 |
| Alpelisib | 180703_BG_10 | 21207 | 0.0284 | 46 | 557 | 13 | 15 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_2 | 603 | 0.0276 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00415 | 0.9916 |
| Alpelisib | 180703_BG_10 | 21490 | 0.0237 | 36 | 474 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_3 | 510 | 0.0232 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00862 | 0.9982 |
| Alpelisib | 180703_BG_12 | 21460 | 0.0306 | 67 | 591 | 13 | 21 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_7 | 658 | 0.0297 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00205 | 0.9975 |
| Alpelisib | 180703_BG_12 | 21518 | 0.0366 | 44 | 745 | 14 | 4 | Alpelisib | 0.00998 | treatment | 72 | 3 | MCF10A-GM_8 | 789 | 0.0354 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00357 | 0.9989 |
| Alpelisib | 180703_BG_10 | 20891 | 0.0207 | 65 | 368 | 13 | 4 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_1 | 433 | 0.0203 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01149 | 0.9840 |
| Alpelisib | 180703_BG_10 | 21247 | 0.0295 | 54 | 575 | 13 | 13 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_2 | 629 | 0.0288 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00305 | 0.9925 |
| Alpelisib | 180703_BG_11 | 20509 | 0.0293 | 99 | 504 | 6 | 7 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_5 | 603 | 0.0286 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00324 | 0.9748 |
| Alpelisib | 180703_BG_11 | 21021 | 0.0297 | 117 | 511 | 14 | 3 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_6 | 628 | 0.0290 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00279 | 0.9871 |
| Alpelisib | 180703_BG_12 | 21075 | 0.0325 | 78 | 609 | 7 | 14 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_8 | 687 | 0.0316 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00023 | 0.9884 |
| Alpelisib | 180703_BG_12 | 22357 | 0.0406 | 76 | 834 | 9 | 15 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_9 | 910 | 0.0391 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00731 | 1.0183 |
| Alpelisib | 180703_BG_11 | 20538 | 0.0297 | 156 | 458 | 9 | 4 | Alpelisib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_5 | 614 | 0.0290 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00277 | 0.9755 |
| Alpelisib | 180703_BG_11 | 19856 | 0.0239 | 119 | 359 | 12 | 21 | Alpelisib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_6 | 478 | 0.0235 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00829 | 0.9587 |
| Alpelisib | 180703_BG_12 | 20218 | 0.0288 | 86 | 499 | 5 | 3 | Alpelisib | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_8 | 585 | 0.0281 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00368 | 0.9677 |
| Neratinib | 180703_BG_11 | 5603 | 0.0372 | 126 | 87 | 9 | 8 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_5 | 213 | 0.0366 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00482 | 0.4228 |
| Neratinib | 180703_BG_11 | 5485 | 0.0430 | 170 | 73 | 3 | 12 | Neratinib | 0.997999609 | treatment | 72 | 3 | MCF10A-GM_4 | 243 | 0.0424 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01062 | 0.4151 |