LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)

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Small Molecule barcode cell_count frac_dead corpse_count cell_count_dead row column agent concentration role timepoint replicate cell_line dead_count fraction_dead cell_count__time0 dead_count__time0 cell_count__ctrl dead_count__ctrl fraction_dead__ctrl increase_fraction_dead GRvalue
Trametinib
180622_BG_8
 8548 0.0162 68 72 10 9
Trametinib
0.003326667
treatment
 72 2
MCF10A-GM_8
 140 0.0161 832.0 168.3 20016 537.9 0.0261 -0.01001 0.6615
Etoposide
180614_BG_03
 1329 0.1005 74 67 8 5
Etoposide
0.997999808
treatment
 72 1
MCF10A-GM_6
 141 0.0959 889.0 105.5 17054 348.0 0.0200 0.07592 0.0989
Etoposide
180622_BG_7
 896 0.1452 82 60 14 16
Etoposide
9.98
treatment
 72 2
MCF10A-GM_6
 142 0.1368 832.0 168.3 20016 537.9 0.0261 0.11068 0.0163
Neratinib
180614_BG_03
 1371 0.1005 42 100 9 20
Neratinib
3.160329364
treatment
 72 1
MCF10A-GM_6
 142 0.0939 889.0 105.5 17054 348.0 0.0200 0.07386 0.1070
Palbociclib
180622_BG_7
 6275 0.0224 78 64 6 9
Palbociclib
0.997999609
treatment
 72 2
MCF10A-GM_5
 142 0.0221 832.0 168.3 20016 537.9 0.0261 -0.00400 0.5532
Trametinib
180622_BG_6
 1781 0.0755 100 42 9 21
Trametinib
0.998
treatment
 72 2
MCF10A-GM_3
 142 0.0738 832.0 168.3 20016 537.9 0.0261 0.04772 0.1804
Etoposide
180703_BG_10
 2016 0.0675 88 54 3 6
Etoposide
0.997999808
treatment
 72 3
MCF10A-GM_1
 142 0.0658 1387.8 74.9 21564 711.9 0.0318 0.03400 0.0989
Trametinib
180622_BG_6
 1675 0.0810 78 64 4 3
Trametinib
0.319359801
treatment
 72 2
MCF10A-GM_2
 142 0.0782 832.0 168.3 20016 537.9 0.0261 0.05203 0.1647
Palbociclib
180614_BG_03
 4021 0.0349 76 67 6 9
Palbociclib
0.997999609
treatment
 72 1
MCF10A-GM_5
 143 0.0343 889.0 105.5 17054 348.0 0.0200 0.01435 0.4249
Etoposide
180703_BG_12
 9932 0.0144 30 113 10 11
Etoposide
0.316033316
treatment
 72 3
MCF10A-GM_9
 143 0.0142 1387.8 74.9 21564 711.9 0.0318 -0.01761 0.6442
Etoposide
180622_BG_7
 952 0.1386 80 63 14 17
Etoposide
3.193598006
treatment
 72 2
MCF10A-GM_6
 143 0.1306 832.0 168.3 20016 537.9 0.0261 0.10447 0.0298
Etoposide
180703_BG_10
 1651 0.0813 107 36 3 4
Etoposide
3.193598006
treatment
 72 3
MCF10A-GM_1
 143 0.0797 1387.8 74.9 21564 711.9 0.0318 0.04791 0.0449
Etoposide
180622_BG_8
 803 0.1612 84 59 8 10
Etoposide
3.193598006
treatment
 72 2
MCF10A-GM_8
 143 0.1512 832.0 168.3 20016 537.9 0.0261 0.12504 -0.0077
Etoposide
180622_BG_7
 751 0.1729 76 67 14 4
Etoposide
3.193598006
treatment
 72 2
MCF10A-GM_5
 143 0.1600 832.0 168.3 20016 537.9 0.0261 0.13383 -0.0221
Etoposide
180622_BG_8
 1742 0.0793 61 82 10 12
Etoposide
0.997999808
treatment
 72 2
MCF10A-GM_8
 143 0.0759 832.0 168.3 20016 537.9 0.0261 0.04974 0.1747
Etoposide
180622_BG_7
 878 0.1488 90 54 6 8
Etoposide
3.193598006
treatment
 72 2
MCF10A-GM_4
 144 0.1409 832.0 168.3 20016 537.9 0.0261 0.11478 0.0118
Trametinib
180614_BG_04
 2597 0.0543 55 89 5 4
Trametinib
0.00998
treatment
 72 1
MCF10A-GM_8
 144 0.0525 889.0 105.5 17054 348.0 0.0200 0.03254 0.2860
Etoposide
180614_BG_02
 4012 0.0355 46 98 10 6
Etoposide
0.316033316
treatment
 72 1
MCF10A-GM_2
 144 0.0346 889.0 105.5 17054 348.0 0.0200 0.01465 0.4242
Palbociclib
180614_BG_03
 6950 0.0206 48 96 12 16
Palbociclib
0.332666627
treatment
 72 1
MCF10A-GM_6
 144 0.0203 889.0 105.5 17054 348.0 0.0200 0.00030 0.6202
Trametinib
180622_BG_6
 1705 0.0800 96 48 8 5
Trametinib
0.319359801
treatment
 72 2
MCF10A-GM_3
 144 0.0779 832.0 168.3 20016 537.9 0.0261 0.05176 0.1693
Palbociclib
180614_BG_02
 7434 0.0193 45 99 5 12
Palbociclib
0.099799997
treatment
 72 1
MCF10A-GM_1
 144 0.0190 889.0 105.5 17054 348.0 0.0200 -0.00099 0.6460
Etoposide
180703_BG_10
 7714 0.0187 42 103 10 6
Etoposide
0.316033316
treatment
 72 3
MCF10A-GM_2
 145 0.0185 1387.8 74.9 21564 711.9 0.0318 -0.01335 0.5425
Palbociclib
180703_BG_12
 8582 0.0168 55 90 9 18
Palbociclib
3.160329361
treatment
 72 3
MCF10A-GM_8
 145 0.0166 1387.8 74.9 21564 711.9 0.0318 -0.01518 0.5846
Palbociclib
180614_BG_04
 3092 0.0455 96 49 4 13
Palbociclib
3.160329361
treatment
 72 1
MCF10A-GM_7
 145 0.0448 889.0 105.5 17054 348.0 0.0200 0.02480 0.3397
Etoposide
180614_BG_03
 1152 0.1158 100 45 7 16
Etoposide
0.997999808
treatment
 72 1
MCF10A-GM_5
 145 0.1118 889.0 105.5 17054 348.0 0.0200 0.09180 0.0627