LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)

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Small Molecule barcode cell_count frac_dead corpse_count cell_count_dead row column agent concentration role timepoint replicate cell_line dead_count fraction_dead cell_count__time0 dead_count__time0 cell_count__ctrl dead_count__ctrl fraction_dead__ctrl increase_fraction_dead GRvalue
Vorinostat
180614_BG_03
17415 0.0189 54 277 9 3
Vorinostat
0.003326667
treatment
72 1
MCF10A-GM_6
331 0.0187 889.0 105.5 17054 348.0 0.0200 -0.00134 1.0098
Vorinostat
180614_BG_02
16445 0.0225 47 324 6 11
Vorinostat
0.003326667
treatment
72 1
MCF10A-GM_2
371 0.0221 889.0 105.5 17054 348.0 0.0200 0.00207 0.9830
Vorinostat
180614_BG_04
16418 0.0235 129 260 12 18
Vorinostat
0.003326667
treatment
72 1
MCF10A-GM_9
389 0.0231 889.0 105.5 17054 348.0 0.0200 0.00315 0.9822
Palbociclib
180614_BG_02
16577 0.0169 35 245 12 17
Palbociclib
0.003326667
treatment
72 1
MCF10A-GM_1
280 0.0166 889.0 105.5 17054 348.0 0.0200 -0.00339 0.9867
Trametinib
180622_BG_6
7466 0.0381 155 135 13 18
Trametinib
0.003326667
treatment
72 2
MCF10A-GM_3
290 0.0374 832.0 168.3 20016 537.9 0.0261 0.01127 0.6132
Palbociclib
180614_BG_03
16771 0.0236 93 305 13 7
Palbociclib
0.003326667
treatment
72 1
MCF10A-GM_6
398 0.0232 889.0 105.5 17054 348.0 0.0200 0.00319 0.9922
Neratinib
180622_BG_6
18955 0.0266 139 369 13 12
Neratinib
0.003326667
treatment
72 2
MCF10A-GM_3
508 0.0261 832.0 168.3 20016 537.9 0.0261 -0.00002 0.9764
Alpelisib
180622_BG_6
20368 0.0292 92 505 12 14
Alpelisib
0.003326667
treatment
72 2
MCF10A-GM_3
597 0.0285 832.0 168.3 20016 537.9 0.0261 0.00235 1.0076
Alpelisib
180614_BG_03
17461 0.0174 55 249 13 15
Alpelisib
0.003326667
treatment
72 1
MCF10A-GM_6
304 0.0171 889.0 105.5 17054 348.0 0.0200 -0.00288 1.0111
Neratinib
180622_BG_8
19948 0.0250 33 466 6 7
Neratinib
0.003326667
treatment
72 2
MCF10A-GM_9
499 0.0244 832.0 168.3 20016 537.9 0.0261 -0.00172 0.9985
Trametinib
180622_BG_7
7553 0.0334 107 149 7 3
Trametinib
0.003326667
treatment
72 2
MCF10A-GM_4
256 0.0328 832.0 168.3 20016 537.9 0.0261 0.00666 0.6173
Trametinib
180622_BG_7
7891 0.0230 50 133 13 21
Trametinib
0.003326667
treatment
72 2
MCF10A-GM_6
183 0.0227 832.0 168.3 20016 537.9 0.0261 -0.00346 0.6328
Alpelisib
180703_BG_10
21342 0.0259 35 518 12 14
Alpelisib
0.003326667
treatment
72 3
MCF10A-GM_3
553 0.0253 1387.8 74.9 21564 711.9 0.0318 -0.00654 0.9948
Etoposide
180622_BG_7
19471 0.0193 45 332 12 18
Etoposide
0.003326667
treatment
72 2
MCF10A-GM_6
377 0.0190 832.0 168.3 20016 537.9 0.0261 -0.00713 0.9880
Dasatinib
180622_BG_7
19473 0.0158 32 276 10 18
Dasatinib
0.003326667
treatment
72 2
MCF10A-GM_5
308 0.0156 832.0 168.3 20016 537.9 0.0261 -0.01055 0.9880
Etoposide
180622_BG_8
21315 0.0229 52 438 11 4
Etoposide
0.003326667
treatment
72 2
MCF10A-GM_7
490 0.0225 832.0 168.3 20016 537.9 0.0261 -0.00365 1.0276
Etoposide
180622_BG_7
20449 0.0260 53 481 10 3
Etoposide
0.003326667
treatment
72 2
MCF10A-GM_4
534 0.0254 832.0 168.3 20016 537.9 0.0261 -0.00068 1.0093
Dasatinib
180622_BG_7
19050 0.0223 41 385 13 18
Dasatinib
0.003326667
treatment
72 2
MCF10A-GM_6
426 0.0219 832.0 168.3 20016 537.9 0.0261 -0.00425 0.9785
Etoposide
180622_BG_7
19564 0.0203 35 362 10 20
Etoposide
0.003326667
treatment
72 2
MCF10A-GM_5
397 0.0199 832.0 168.3 20016 537.9 0.0261 -0.00624 0.9901
Etoposide
180622_BG_8
19762 0.0243 31 450 11 7
Etoposide
0.003326667
treatment
72 2
MCF10A-GM_8
481 0.0238 832.0 168.3 20016 537.9 0.0261 -0.00236 0.9944
Dasatinib
180622_BG_8
20978 0.0317 59 608 11 19
Dasatinib
0.003326667
treatment
72 2
MCF10A-GM_9
667 0.0308 832.0 168.3 20016 537.9 0.0261 0.00469 1.0206
Dasatinib
180622_BG_6
18449 0.0243 99 351 12 4
Dasatinib
0.003326667
treatment
72 2
MCF10A-GM_3
450 0.0238 832.0 168.3 20016 537.9 0.0261 -0.00231 0.9648
Dasatinib
180622_BG_7
19501 0.0232 68 386 10 17
Dasatinib
0.003326667
treatment
72 2
MCF10A-GM_4
454 0.0228 832.0 168.3 20016 537.9 0.0261 -0.00337 0.9887
Dasatinib
180622_BG_8
17506 0.0248 53 383 6 19
Dasatinib
0.003326667
treatment
72 2
MCF10A-GM_7
436 0.0243 832.0 168.3 20016 537.9 0.0261 -0.00182 0.9424
Etoposide
180622_BG_8
19941 0.0272 49 495 14 8
Etoposide
0.003326667
treatment
72 2
MCF10A-GM_9
544 0.0266 832.0 168.3 20016 537.9 0.0261 0.00043 0.9984