LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dasatinib | 180622_BG_6 | 4577 | 0.1002 | 132 | 340 | 3 | 22 | Dasatinib | 0.997999808 | treatment | 72 | 2 | MCF10A-GM_1 | 472 | 0.0935 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.06736 | 0.4500 |
Trametinib | 180703_BG_11 | 3257 | 0.0486 | 115 | 49 | 6 | 22 | Trametinib | 0.319359801 | treatment | 72 | 3 | MCF10A-GM_4 | 164 | 0.0479 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01614 | 0.2405 |
Vorinostat | 180614_BG_04 | 16773 | 0.0196 | 91 | 239 | 5 | 22 | Vorinostat | 0.00998 | treatment | 72 | 1 | MCF10A-GM_8 | 330 | 0.0193 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00070 | 0.9922 |
Palbociclib | 180614_BG_02 | 15116 | 0.0159 | 23 | 218 | 14 | 22 | Palbociclib | 0.00998 | treatment | 72 | 1 | MCF10A-GM_3 | 241 | 0.0157 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00430 | 0.9442 |
Etoposide | 180703_BG_12 | 15802 | 0.0229 | 81 | 283 | 3 | 22 | Etoposide | 0.099799999 | treatment | 72 | 3 | MCF10A-GM_7 | 364 | 0.0225 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00928 | 0.8489 |
Taxol | 180703_BG_11 | 762 | 0.8628 | 295 | 617 | 10 | 22 | Paclitaxel | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_4 | 912 | 0.5448 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.51300 | -0.1406 |