LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)

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Small Molecule barcode cell_count frac_dead corpse_count cell_count_dead row column agent concentration role timepoint replicate cell_line dead_count fraction_dead cell_count__time0 dead_count__time0 cell_count__ctrl dead_count__ctrl fraction_dead__ctrl increase_fraction_dead GRvalue
Trametinib
180622_BG_7
 2569 0.0500 72 60 12 3
Trametinib
0.00998
treatment
 72 2
MCF10A-GM_5
 132 0.0489 832.0 168.3 20016 537.9 0.0261 0.02275 0.2785
Palbociclib
180614_BG_04
 3499 0.0383 77 60 9 18
Palbociclib
3.160329361
treatment
 72 1
MCF10A-GM_8
 137 0.0377 889.0 105.5 17054 348.0 0.0200 0.01768 0.3792
Palbociclib
180614_BG_03
 4268 0.0344 90 60 6 6
Palbociclib
0.997999609
treatment
 72 1
MCF10A-GM_4
 150 0.0340 889.0 105.5 17054 348.0 0.0200 0.01396 0.4450
Etoposide
180622_BG_7
 896 0.1452 82 60 14 16
Etoposide
9.98
treatment
 72 2
MCF10A-GM_6
 142 0.1368 832.0 168.3 20016 537.9 0.0261 0.11068 0.0163
Palbociclib
180703_BG_11
 6708 0.0269 124 60 6 18
Palbociclib
3.160329361
treatment
 72 3
MCF10A-GM_4
 184 0.0267 1387.8 74.9 21564 711.9 0.0318 -0.00510 0.4890
Neratinib
180614_BG_03
 1766 0.0627 53 61 9 8
Neratinib
0.997999609
treatment
 72 1
MCF10A-GM_5
 114 0.0606 889.0 105.5 17054 348.0 0.0200 0.04064 0.1748
Trametinib
180703_BG_12
 4419 0.0300 74 61 7 22
Trametinib
0.00998
treatment
 72 3
MCF10A-GM_9
 135 0.0296 1387.8 74.9 21564 711.9 0.0318 -0.00215 0.3400
Etoposide
180622_BG_6
 1052 0.1024 52 61 6 18
Etoposide
0.997999808
treatment
 72 2
MCF10A-GM_3
 113 0.0970 832.0 168.3 20016 537.9 0.0261 0.07087 0.0525
Neratinib
180614_BG_03
 1577 0.0829 76 61 3 12
Neratinib
0.997999609
treatment
 72 1
MCF10A-GM_4
 137 0.0799 889.0 105.5 17054 348.0 0.0200 0.05993 0.1440
Palbociclib
180614_BG_02
 3863 0.0308 60 61 12 13
Palbociclib
0.997999609
treatment
 72 1
MCF10A-GM_3
 121 0.0304 889.0 105.5 17054 348.0 0.0200 0.01038 0.4116
Palbociclib
180622_BG_6
 4949 0.0401 143 61 7 13
Palbociclib
0.997999609
treatment
 72 2
MCF10A-GM_1
 204 0.0396 832.0 168.3 20016 537.9 0.0261 0.01346 0.4749
Vorinostat
180703_BG_12
 2107 0.0563 61 61 12 16
Vorinostat
9.98
treatment
 72 3
MCF10A-GM_9
 122 0.0547 1387.8 74.9 21564 711.9 0.0318 0.02293 0.1113
Neratinib
180622_BG_8
 1764 0.0705 67 62 4 22
Neratinib
3.160329364
treatment
 72 2
MCF10A-GM_7
 129 0.0681 832.0 168.3 20016 537.9 0.0261 0.04202 0.1780
Etoposide
180614_BG_04
 1143 0.1317 102 62 12 4
Etoposide
3.193598006
treatment
 72 1
MCF10A-GM_9
 164 0.1255 889.0 105.5 17054 348.0 0.0200 0.10548 0.0608
Neratinib
180703_BG_11
 2697 0.0692 134 62 9 20
Neratinib
3.160329364
treatment
 72 3
MCF10A-GM_6
 196 0.0677 1387.8 74.9 21564 711.9 0.0318 0.03595 0.1828
Vorinostat
180614_BG_04
 2822 0.0701 146 62 9 17
Vorinostat
3.193598006
treatment
 72 1
MCF10A-GM_8
 208 0.0686 889.0 105.5 17054 348.0 0.0200 0.04865 0.3113
Etoposide
180614_BG_02
 1107 0.0945 47 62 6 18
Etoposide
0.997999808
treatment
 72 1
MCF10A-GM_3
 109 0.0896 889.0 105.5 17054 348.0 0.0200 0.06964 0.0528
Etoposide
180703_BG_11
 2406 0.0829 150 62 8 5
Etoposide
0.997999808
treatment
 72 3
MCF10A-GM_5
 212 0.0810 1387.8 74.9 21564 711.9 0.0318 0.04918 0.1492
Palbociclib
180622_BG_6
 5819 0.0292 111 62 4 21
Palbociclib
0.332666627
treatment
 72 2
MCF10A-GM_2
 173 0.0289 832.0 168.3 20016 537.9 0.0261 0.00275 0.5279
Trametinib
180703_BG_10
 3119 0.0384 60 62 4 3
Trametinib
0.319359801
treatment
 72 3
MCF10A-GM_2
 122 0.0376 1387.8 74.9 21564 711.9 0.0318 0.00584 0.2270
Neratinib
180614_BG_03
 4630 0.0318 88 62 14 9
Neratinib
0.299399965
treatment
 72 1
MCF10A-GM_6
 150 0.0314 889.0 105.5 17054 348.0 0.0200 0.01139 0.4729
Trametinib
180614_BG_02
 1752 0.0570 39 63 6 4
Trametinib
0.031603332
treatment
 72 1
MCF10A-GM_1
 102 0.0550 889.0 105.5 17054 348.0 0.0200 0.03502 0.1726
Palbociclib
180703_BG_12
 6136 0.0238 85 63 7 20
Palbociclib
10.01326667
treatment
 72 3
MCF10A-GM_8
 148 0.0236 1387.8 74.9 21564 711.9 0.0318 -0.00825 0.4558
Etoposide
180622_BG_7
 952 0.1386 80 63 14 17
Etoposide
3.193598006
treatment
 72 2
MCF10A-GM_6
 143 0.1306 832.0 168.3 20016 537.9 0.0261 0.10447 0.0298
Trametinib
180703_BG_11
 3117 0.0571 122 63 8 10
Trametinib
0.998
treatment
 72 3
MCF10A-GM_4
 185 0.0560 1387.8 74.9 21564 711.9 0.0318 0.02423 0.2268