LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | 180703_BG_11 | 22225 | 0.0365 | 127 | 689 | 13 | 17 | Paclitaxel | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_6 | 816 | 0.0354 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00362 | 1.0153 |
| Vorinostat | 180703_BG_12 | 22260 | 0.0388 | 76 | 791 | 7 | 17 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_8 | 867 | 0.0375 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00569 | 1.0161 |
| Alpelisib | 180703_BG_12 | 22357 | 0.0406 | 76 | 834 | 9 | 15 | Alpelisib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_9 | 910 | 0.0391 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00731 | 1.0183 |
| Vorinostat | 180703_BG_12 | 22383 | 0.0365 | 63 | 756 | 8 | 12 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_8 | 819 | 0.0353 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00350 | 1.0189 |
| Palbociclib | 180703_BG_10 | 22434 | 0.0331 | 41 | 704 | 13 | 10 | Palbociclib | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_3 | 745 | 0.0321 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00034 | 1.0201 |
| Vorinostat | 180703_BG_10 | 22679 | 0.0345 | 62 | 723 | 5 | 13 | Vorinostat | 0.003326667 | treatment | 72 | 3 | MCF10A-GM_1 | 785 | 0.0335 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00166 | 1.0256 |