LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Taxol | 180614_BG_03 | 429 | 1.0726 | 287 | 481 | 10 | 22 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_4 | 768 | 0.6416 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.62161 | -0.1571 |
| Taxol | 180622_BG_7 | 429 | 1.0117 | 252 | 437 | 10 | 14 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_6 | 689 | 0.6163 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.59015 | -0.1344 |
| Taxol | 180614_BG_02 | 431 | 0.9606 | 254 | 404 | 4 | 18 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_1 | 658 | 0.6042 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.58423 | -0.1562 |
| Taxol | 180614_BG_04 | 434 | 0.8690 | 253 | 344 | 14 | 5 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_8 | 597 | 0.5790 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.55905 | -0.1548 |
| Taxol | 180622_BG_8 | 438 | 0.9769 | 255 | 422 | 11 | 18 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_9 | 677 | 0.6072 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.58105 | -0.1305 |
| Taxol | 180614_BG_04 | 454 | 0.7472 | 175 | 295 | 14 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_8 | 470 | 0.5087 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.48866 | -0.1459 |
| Taxol | 180614_BG_04 | 455 | 0.9558 | 360 | 419 | 9 | 13 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_7 | 779 | 0.6313 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.61128 | -0.1454 |
| Taxol | 180622_BG_6 | 456 | 0.9322 | 340 | 402 | 12 | 16 | Paclitaxel | 0.031603332 | treatment | 72 | 2 | MCF10A-GM_3 | 742 | 0.6194 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.59324 | -0.1228 |
| Taxol | 180614_BG_02 | 456 | 0.9386 | 212 | 415 | 4 | 14 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_1 | 627 | 0.5789 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.55895 | -0.1450 |
| Taxol | 180614_BG_03 | 457 | 0.9960 | 301 | 454 | 14 | 20 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_6 | 755 | 0.6229 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.60294 | -0.1445 |
| Taxol | 180614_BG_04 | 457 | 0.9737 | 378 | 435 | 3 | 20 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_6 | 813 | 0.6402 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.62016 | -0.1445 |
| Taxol | 180614_BG_02 | 459 | 1.0098 | 254 | 466 | 6 | 7 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_3 | 720 | 0.6107 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.59069 | -0.1437 |
| Taxol | 180614_BG_04 | 477 | 0.9887 | 499 | 466 | 7 | 21 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_4 | 965 | 0.6692 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.64921 | -0.1359 |
| Taxol | 180614_BG_03 | 477 | 1.0317 | 311 | 502 | 4 | 12 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_4 | 813 | 0.6302 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.61024 | -0.1359 |
| Taxol | 180614_BG_02 | 480 | 0.9858 | 295 | 469 | 8 | 3 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_3 | 764 | 0.6141 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.59415 | -0.1346 |
| Taxol | 180614_BG_03 | 491 | 0.8576 | 183 | 395 | 11 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_5 | 578 | 0.5407 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.52070 | -0.1300 |
| Taxol | 180614_BG_02 | 496 | 0.9299 | 260 | 443 | 5 | 14 | Paclitaxel | 0.099799981 | treatment | 72 | 1 | MCF10A-GM_2 | 703 | 0.5863 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.56633 | -0.1280 |
| Taxol | 180614_BG_04 | 509 | 0.9809 | 379 | 492 | 10 | 22 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_7 | 871 | 0.6312 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.61116 | -0.1226 |
| Taxol | 180614_BG_02 | 515 | 0.6846 | 100 | 321 | 7 | 19 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_2 | 421 | 0.4498 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.42979 | -0.1202 |
| Taxol | 180614_BG_03 | 552 | 0.6955 | 141 | 341 | 13 | 9 | Paclitaxel | 0.312706472 | treatment | 72 | 1 | MCF10A-GM_6 | 482 | 0.4662 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.44616 | -0.1058 |
| Etoposide | 180622_BG_6 | 559 | 0.2760 | 162 | 37 | 6 | 22 | Etoposide | 9.98 | treatment | 72 | 2 | MCF10A-GM_2 | 199 | 0.2625 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.23641 | -0.0830 |
| Taxol | 180703_BG_10 | 621 | 0.9095 | 230 | 544 | 4 | 18 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_1 | 774 | 0.5548 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.52304 | -0.1839 |
| Taxol | 180703_BG_10 | 624 | 0.9057 | 224 | 544 | 8 | 3 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_3 | 768 | 0.5517 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.51993 | -0.1829 |
| Taxol | 180703_BG_11 | 649 | 1.0786 | 522 | 741 | 11 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_5 | 1263 | 0.6606 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.62877 | -0.1747 |
| Taxol | 180703_BG_12 | 652 | 0.8599 | 326 | 515 | 14 | 15 | Paclitaxel | 0.312706472 | treatment | 72 | 3 | MCF10A-GM_9 | 841 | 0.5633 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.53150 | -0.1738 |