LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Trametinib | 180703_BG_12 | 19386 | 0.0261 | 96 | 413 | 7 | 11 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_8 | 509 | 0.0256 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00621 | 0.9469 |
| Trametinib | 180703_BG_12 | 19556 | 0.0249 | 47 | 441 | 12 | 19 | Trametinib | 0.000332667 | treatment | 72 | 3 | MCF10A-GM_9 | 488 | 0.0243 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00745 | 0.9512 |
| Vorinostat | 180703_BG_12 | 21761 | 0.0411 | 65 | 833 | 5 | 12 | Vorinostat | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_7 | 898 | 0.0396 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00783 | 1.0046 |
| Trametinib | 180703_BG_12 | 2844 | 0.0338 | 57 | 41 | 6 | 13 | Trametinib | 0.099799981 | treatment | 72 | 3 | MCF10A-GM_7 | 98 | 0.0333 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00151 | 0.1988 |
| Etoposide | 180703_BG_12 | 19425 | 0.0259 | 53 | 451 | 4 | 10 | Etoposide | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_8 | 504 | 0.0253 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00651 | 0.9479 |
| Dasatinib | 180703_BG_12 | 18428 | 0.0240 | 94 | 350 | 3 | 8 | Dasatinib | 0.033266667 | treatment | 72 | 3 | MCF10A-GM_7 | 444 | 0.0235 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00827 | 0.9221 |