LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vorinostat | 180703_BG_11 | 20563 | 0.0347 | 105 | 613 | 11 | 3 | Vorinostat | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_6 | 718 | 0.0337 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00194 | 0.9761 |
| Vorinostat | 180703_BG_12 | 20897 | 0.0383 | 84 | 719 | 3 | 4 | Vorinostat | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_7 | 803 | 0.0370 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00521 | 0.9842 |
| Vorinostat | 180703_BG_12 | 20428 | 0.0395 | 72 | 737 | 6 | 15 | Vorinostat | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_8 | 809 | 0.0381 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00629 | 0.9728 |
| Vorinostat | 180703_BG_12 | 20374 | 0.0288 | 37 | 551 | 12 | 15 | Vorinostat | 0.316033316 | treatment | 72 | 3 | MCF10A-GM_9 | 588 | 0.0281 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00375 | 0.9715 |
| Vorinostat | 180703_BG_10 | 11873 | 0.0259 | 73 | 236 | 5 | 5 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_1 | 309 | 0.0254 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00643 | 0.7201 |
| Vorinostat | 180703_BG_10 | 11794 | 0.0179 | 43 | 169 | 7 | 10 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_2 | 212 | 0.0177 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01414 | 0.7172 |
| Vorinostat | 180703_BG_10 | 12049 | 0.0194 | 52 | 183 | 8 | 8 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_3 | 235 | 0.0191 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01267 | 0.7265 |
| Vorinostat | 180703_BG_11 | 14601 | 0.0294 | 138 | 296 | 6 | 20 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_4 | 434 | 0.0289 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00293 | 0.8123 |
| Vorinostat | 180703_BG_11 | 14992 | 0.0253 | 120 | 262 | 12 | 17 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_5 | 382 | 0.0248 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00695 | 0.8245 |
| Vorinostat | 180703_BG_11 | 15624 | 0.0244 | 139 | 245 | 14 | 21 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_6 | 384 | 0.0240 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00781 | 0.8436 |
| Vorinostat | 180703_BG_12 | 17269 | 0.0256 | 82 | 362 | 3 | 9 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_7 | 444 | 0.0251 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00673 | 0.8908 |
| Vorinostat | 180703_BG_12 | 15968 | 0.0212 | 48 | 291 | 6 | 18 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_8 | 339 | 0.0208 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01101 | 0.8538 |
| Vorinostat | 180703_BG_12 | 15683 | 0.0175 | 32 | 243 | 10 | 8 | Vorinostat | 0.997999808 | treatment | 72 | 3 | MCF10A-GM_9 | 275 | 0.0172 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.01457 | 0.8454 |
| Vorinostat | 180703_BG_10 | 3180 | 0.0409 | 51 | 81 | 6 | 20 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_1 | 132 | 0.0399 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00806 | 0.2331 |
| Vorinostat | 180703_BG_10 | 3468 | 0.0387 | 69 | 68 | 7 | 8 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_2 | 137 | 0.0380 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00620 | 0.2604 |
| Vorinostat | 180703_BG_10 | 3533 | 0.0350 | 72 | 54 | 11 | 12 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_3 | 126 | 0.0344 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.00264 | 0.2663 |
| Vorinostat | 180703_BG_11 | 4447 | 0.0628 | 189 | 102 | 7 | 13 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_4 | 291 | 0.0614 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.02962 | 0.3421 |
| Vorinostat | 180703_BG_11 | 4990 | 0.0515 | 194 | 73 | 9 | 11 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_5 | 267 | 0.0508 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01899 | 0.3817 |
| Vorinostat | 180703_BG_11 | 4939 | 0.0469 | 135 | 103 | 12 | 10 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_6 | 238 | 0.0460 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.01417 | 0.3781 |
| Vorinostat | 180703_BG_12 | 5619 | 0.0245 | 63 | 76 | 6 | 6 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_7 | 139 | 0.0241 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00766 | 0.4238 |
| Vorinostat | 180703_BG_12 | 5682 | 0.0302 | 85 | 89 | 9 | 17 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_8 | 174 | 0.0297 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00209 | 0.4278 |
| Vorinostat | 180703_BG_12 | 7024 | 0.0242 | 78 | 94 | 10 | 17 | Vorinostat | 3.193598006 | treatment | 72 | 3 | MCF10A-GM_9 | 172 | 0.0239 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | -0.00790 | 0.5064 |
| Vorinostat | 180703_BG_10 | 1946 | 0.0651 | 81 | 51 | 10 | 16 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_1 | 132 | 0.0635 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.03172 | 0.0892 |
| Vorinostat | 180703_BG_10 | 1669 | 0.0905 | 87 | 72 | 11 | 5 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_2 | 159 | 0.0870 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.05518 | 0.0477 |
| Vorinostat | 180703_BG_10 | 1832 | 0.1014 | 121 | 77 | 13 | 5 | Vorinostat | 9.98 | treatment | 72 | 3 | MCF10A-GM_3 | 198 | 0.0975 | 1387.8 | 74.9 | 21564 | 711.9 | 0.0318 | 0.06574 | 0.0727 |