LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
Download: Excel (XLSX), Comma-separated (CSV)
| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Palbociclib | 180622_BG_6 | 3314 | 0.0437 | 96 | 53 | 6 | 15 | Palbociclib | 3.160329361 | treatment | 72 | 2 | MCF10A-GM_2 | 149 | 0.0430 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.01690 | 0.3515 |
| Palbociclib | 180622_BG_6 | 3476 | 0.0558 | 143 | 59 | 11 | 4 | Palbociclib | 3.160329361 | treatment | 72 | 2 | MCF10A-GM_3 | 202 | 0.0549 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.02880 | 0.3656 |
| Palbociclib | 180622_BG_7 | 3865 | 0.0280 | 64 | 46 | 6 | 18 | Palbociclib | 3.160329361 | treatment | 72 | 2 | MCF10A-GM_4 | 110 | 0.0277 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.00155 | 0.3976 |
| Palbociclib | 180622_BG_7 | 5106 | 0.0161 | 40 | 43 | 10 | 16 | Palbociclib | 3.160329361 | treatment | 72 | 2 | MCF10A-GM_5 | 83 | 0.0160 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.01013 | 0.4850 |
| Palbociclib | 180622_BG_7 | 4664 | 0.0223 | 55 | 50 | 11 | 18 | Palbociclib | 3.160329361 | treatment | 72 | 2 | MCF10A-GM_6 | 105 | 0.0220 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00411 | 0.4560 |
| Palbociclib | 180622_BG_8 | 5568 | 0.0180 | 42 | 59 | 4 | 13 | Palbociclib | 3.160329361 | treatment | 72 | 2 | MCF10A-GM_7 | 101 | 0.0178 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00831 | 0.5133 |
| Palbociclib | 180622_BG_8 | 6092 | 0.0220 | 53 | 82 | 9 | 18 | Palbociclib | 3.160329361 | treatment | 72 | 2 | MCF10A-GM_8 | 135 | 0.0217 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00445 | 0.5433 |
| Palbociclib | 180622_BG_8 | 4876 | 0.0205 | 57 | 44 | 11 | 20 | Palbociclib | 3.160329361 | treatment | 72 | 2 | MCF10A-GM_9 | 101 | 0.0203 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00583 | 0.4702 |
| Trametinib | 180622_BG_6 | 16950 | 0.0173 | 68 | 227 | 9 | 20 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_1 | 295 | 0.0171 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00902 | 0.9288 |
| Trametinib | 180622_BG_6 | 17616 | 0.0230 | 87 | 320 | 10 | 4 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_2 | 407 | 0.0226 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00354 | 0.9451 |
| Trametinib | 180622_BG_6 | 18309 | 0.0249 | 95 | 363 | 11 | 11 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_3 | 458 | 0.0244 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00172 | 0.9615 |
| Trametinib | 180622_BG_7 | 16892 | 0.0233 | 60 | 335 | 3 | 19 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_4 | 395 | 0.0228 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00328 | 0.9274 |
| Trametinib | 180622_BG_7 | 14574 | 0.0236 | 66 | 280 | 4 | 17 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_5 | 346 | 0.0232 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00293 | 0.8664 |
| Trametinib | 180622_BG_7 | 18351 | 0.0235 | 57 | 376 | 14 | 19 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_6 | 433 | 0.0231 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00307 | 0.9625 |
| Trametinib | 180622_BG_8 | 18514 | 0.0264 | 56 | 434 | 5 | 16 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_7 | 490 | 0.0258 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00034 | 0.9663 |
| Trametinib | 180622_BG_8 | 18055 | 0.0259 | 57 | 412 | 7 | 11 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_8 | 469 | 0.0253 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00081 | 0.9556 |
| Trametinib | 180622_BG_8 | 20574 | 0.0235 | 48 | 437 | 12 | 19 | Trametinib | 0.000332667 | treatment | 72 | 2 | MCF10A-GM_9 | 485 | 0.0230 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00309 | 1.0120 |
| Trametinib | 180622_BG_6 | 9730 | 0.0184 | 106 | 75 | 6 | 8 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_1 | 181 | 0.0183 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00786 | 0.7091 |
| Trametinib | 180622_BG_6 | 14842 | 0.0175 | 74 | 187 | 10 | 19 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_2 | 261 | 0.0173 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00884 | 0.8738 |
| Trametinib | 180622_BG_6 | 13564 | 0.0248 | 117 | 222 | 14 | 21 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_3 | 339 | 0.0244 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00174 | 0.8374 |
| Trametinib | 180622_BG_7 | 13884 | 0.0281 | 87 | 305 | 5 | 5 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_4 | 392 | 0.0275 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | 0.00133 | 0.8467 |
| Trametinib | 180622_BG_7 | 13214 | 0.0204 | 90 | 182 | 7 | 15 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_5 | 272 | 0.0202 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00596 | 0.8269 |
| Trametinib | 180622_BG_7 | 12505 | 0.0234 | 77 | 218 | 7 | 21 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_6 | 295 | 0.0230 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00308 | 0.8051 |
| Trametinib | 180622_BG_8 | 15536 | 0.0211 | 52 | 277 | 4 | 18 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_7 | 329 | 0.0207 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00539 | 0.8925 |
| Trametinib | 180622_BG_8 | 15486 | 0.0234 | 50 | 314 | 9 | 19 | Trametinib | 0.000998 | treatment | 72 | 2 | MCF10A-GM_8 | 364 | 0.0230 | 832.0 | 168.3 | 20016 | 537.9 | 0.0261 | -0.00316 | 0.8912 |