LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset - HMS LINCS Database

LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)

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Small Molecule	barcode	cell_count	frac_dead	corpse_count	cell_count_dead	row	column	agent	concentration	role	timepoint	replicate	cell_line	dead_count	fraction_dead	cell_count__time0	dead_count__time0	cell_count__ctrl	dead_count__ctrl	fraction_dead__ctrl	increase_fraction_dead	GRvalue
Taxol	180622_BG_8	322	1.2092	328	458	10	22	Paclitaxel	0.312706472	treatment	72	2	MCF10A-GM_8	786	0.7094	832.0	168.3	20016	537.9	0.0261	0.68326	-0.1869
Taxol	180622_BG_8	298	1.2594	338	463	14	15	Paclitaxel	0.312706472	treatment	72	2	MCF10A-GM_9	801	0.7288	832.0	168.3	20016	537.9	0.0261	0.70272	-0.2005
Palbociclib	180622_BG_6	18289	0.0217	75	323	10	12	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_1	398	0.0213	832.0	168.3	20016	537.9	0.0261	-0.00483	0.9610
Palbociclib	180622_BG_6	20528	0.0230	114	361	11	9	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_2	475	0.0226	832.0	168.3	20016	537.9	0.0261	-0.00351	1.0110
Palbociclib	180622_BG_6	20042	0.0259	100	421	14	10	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_3	521	0.0253	832.0	168.3	20016	537.9	0.0261	-0.00079	1.0006
Palbociclib	180622_BG_7	18570	0.0253	75	396	6	19	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_4	471	0.0247	832.0	168.3	20016	537.9	0.0261	-0.00139	0.9676
Palbociclib	180622_BG_7	20784	0.0241	36	466	12	14	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_5	502	0.0236	832.0	168.3	20016	537.9	0.0261	-0.00254	1.0165
Palbociclib	180622_BG_7	18103	0.0252	60	397	13	6	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_6	457	0.0246	832.0	168.3	20016	537.9	0.0261	-0.00150	0.9567
Palbociclib	180622_BG_8	19956	0.0210	43	377	8	20	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_7	420	0.0206	832.0	168.3	20016	537.9	0.0261	-0.00551	0.9987
Palbociclib	180622_BG_8	20242	0.0264	39	496	12	6	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_8	535	0.0257	832.0	168.3	20016	537.9	0.0261	-0.00038	1.0049
Palbociclib	180622_BG_8	19516	0.0272	49	484	13	6	Palbociclib	0.001081167	treatment	72	2	MCF10A-GM_9	533	0.0266	832.0	168.3	20016	537.9	0.0261	0.00046	0.9890
Palbociclib	180622_BG_6	16945	0.0198	53	284	12	17	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_1	337	0.0195	832.0	168.3	20016	537.9	0.0261	-0.00662	0.9287
Palbociclib	180622_BG_6	20385	0.0339	137	559	13	8	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_2	696	0.0330	832.0	168.3	20016	537.9	0.0261	0.00689	1.0080
Palbociclib	180622_BG_6	19193	0.0261	123	382	13	10	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_3	505	0.0256	832.0	168.3	20016	537.9	0.0261	-0.00049	0.9818
Palbociclib	180622_BG_7	19140	0.0323	71	550	6	3	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_4	621	0.0314	832.0	168.3	20016	537.9	0.0261	0.00530	0.9806
Palbociclib	180622_BG_7	18913	0.0243	63	398	8	15	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_5	461	0.0238	832.0	168.3	20016	537.9	0.0261	-0.00233	0.9754
Palbociclib	180622_BG_7	19061	0.0285	78	467	13	7	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_6	545	0.0278	832.0	168.3	20016	537.9	0.0261	0.00167	0.9788
Palbociclib	180622_BG_8	21027	0.0285	34	567	4	15	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_7	601	0.0278	832.0	168.3	20016	537.9	0.0261	0.00166	1.0216
Palbociclib	180622_BG_8	19879	0.0296	78	513	7	5	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_8	591	0.0289	832.0	168.3	20016	537.9	0.0261	0.00275	0.9970
Palbociclib	180622_BG_8	20360	0.0264	36	502	8	7	Palbociclib	0.003326667	treatment	72	2	MCF10A-GM_9	538	0.0257	832.0	168.3	20016	537.9	0.0261	-0.00038	1.0074
Palbociclib	180622_BG_6	17818	0.0292	123	401	5	22	Palbociclib	0.00998	treatment	72	2	MCF10A-GM_1	524	0.0286	832.0	168.3	20016	537.9	0.0261	0.00244	0.9499
Palbociclib	180622_BG_6	18022	0.0225	72	336	6	3	Palbociclib	0.00998	treatment	72	2	MCF10A-GM_2	408	0.0221	832.0	168.3	20016	537.9	0.0261	-0.00399	0.9548
Palbociclib	180622_BG_6	18406	0.0258	93	384	14	22	Palbociclib	0.00998	treatment	72	2	MCF10A-GM_3	477	0.0253	832.0	168.3	20016	537.9	0.0261	-0.00086	0.9638
Palbociclib	180622_BG_7	19716	0.0197	45	344	12	22	Palbociclib	0.00998	treatment	72	2	MCF10A-GM_4	389	0.0193	832.0	168.3	20016	537.9	0.0261	-0.00678	0.9934
Palbociclib	180622_BG_7	17831	0.0202	50	311	13	10	Palbociclib	0.00998	treatment	72	2	MCF10A-GM_5	361	0.0198	832.0	168.3	20016	537.9	0.0261	-0.00628	0.9502

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HMS LINCS Project

LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)