LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Repeat performed by Scientist B in 2019 to assess reproducibility. Dataset 1 of 2: Normalized growth rate inhibition values. - Dataset (ID:20359)
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| Small Molecule | barcode | cell_count | frac_dead | corpse_count | cell_count_dead | row | column | agent | concentration | role | timepoint | replicate | cell_line | dead_count | fraction_dead | cell_count__time0 | dead_count__time0 | cell_count__ctrl | dead_count__ctrl | fraction_dead__ctrl | increase_fraction_dead | GRvalue |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Vorinostat | 180614_BG_02 | 7763 | 0.0210 | 54 | 110 | 7 | 10 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_2 | 164 | 0.0207 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00069 | 0.6628 |
| Vorinostat | 180614_BG_02 | 7231 | 0.0217 | 43 | 115 | 8 | 8 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_3 | 158 | 0.0214 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00139 | 0.6353 |
| Vorinostat | 180614_BG_03 | 8053 | 0.0291 | 95 | 142 | 6 | 20 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_4 | 237 | 0.0286 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00859 | 0.6771 |
| Vorinostat | 180614_BG_03 | 8633 | 0.0191 | 71 | 95 | 12 | 17 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_5 | 166 | 0.0189 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | -0.00113 | 0.7047 |
| Vorinostat | 180614_BG_03 | 8956 | 0.0258 | 79 | 154 | 14 | 21 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_6 | 233 | 0.0254 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00536 | 0.7195 |
| Vorinostat | 180614_BG_04 | 8637 | 0.0359 | 156 | 160 | 3 | 9 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_7 | 316 | 0.0353 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01530 | 0.7049 |
| Vorinostat | 180614_BG_04 | 8646 | 0.0277 | 116 | 127 | 6 | 18 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_8 | 243 | 0.0273 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00734 | 0.7053 |
| Vorinostat | 180614_BG_04 | 9547 | 0.0283 | 111 | 162 | 10 | 8 | Vorinostat | 0.997999808 | treatment | 72 | 1 | MCF10A-GM_9 | 273 | 0.0278 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00780 | 0.7455 |
| Vorinostat | 180614_BG_02 | 2414 | 0.0291 | 25 | 46 | 6 | 20 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_1 | 71 | 0.0286 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.00858 | 0.2642 |
| Vorinostat | 180614_BG_02 | 2488 | 0.0364 | 67 | 26 | 7 | 8 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_2 | 93 | 0.0360 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01604 | 0.2731 |
| Vorinostat | 180614_BG_02 | 2227 | 0.0439 | 49 | 51 | 11 | 12 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_3 | 100 | 0.0430 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02298 | 0.2405 |
| Vorinostat | 180614_BG_03 | 2099 | 0.0586 | 86 | 42 | 7 | 13 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_4 | 128 | 0.0575 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.03748 | 0.2233 |
| Vorinostat | 180614_BG_03 | 2619 | 0.0368 | 68 | 31 | 9 | 11 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_5 | 99 | 0.0364 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01643 | 0.2886 |
| Vorinostat | 180614_BG_03 | 2336 | 0.0392 | 59 | 35 | 12 | 10 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_6 | 94 | 0.0387 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01869 | 0.2544 |
| Vorinostat | 180614_BG_04 | 2599 | 0.0659 | 133 | 47 | 6 | 6 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_7 | 180 | 0.0648 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04478 | 0.2862 |
| Vorinostat | 180614_BG_04 | 2822 | 0.0701 | 146 | 62 | 9 | 17 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_8 | 208 | 0.0686 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04865 | 0.3113 |
| Vorinostat | 180614_BG_04 | 3134 | 0.0361 | 79 | 37 | 10 | 17 | Vorinostat | 3.193598006 | treatment | 72 | 1 | MCF10A-GM_9 | 116 | 0.0357 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.01570 | 0.3440 |
| Vorinostat | 180614_BG_02 | 1234 | 0.0436 | 28 | 27 | 10 | 16 | Vorinostat | 9.98 | treatment | 72 | 1 | MCF10A-GM_1 | 55 | 0.0427 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.02267 | 0.0800 |
| Vorinostat | 180614_BG_02 | 1112 | 0.0876 | 64 | 39 | 11 | 5 | Vorinostat | 9.98 | treatment | 72 | 1 | MCF10A-GM_2 | 103 | 0.0848 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.06478 | 0.0539 |
| Vorinostat | 180614_BG_02 | 1154 | 0.0977 | 84 | 37 | 13 | 5 | Vorinostat | 9.98 | treatment | 72 | 1 | MCF10A-GM_3 | 121 | 0.0949 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.07491 | 0.0631 |
| Vorinostat | 180614_BG_03 | 1320 | 0.1058 | 117 | 35 | 4 | 19 | Vorinostat | 9.98 | treatment | 72 | 1 | MCF10A-GM_4 | 152 | 0.1033 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.08327 | 0.0972 |
| Vorinostat | 180614_BG_03 | 1247 | 0.1071 | 107 | 38 | 5 | 17 | Vorinostat | 9.98 | treatment | 72 | 1 | MCF10A-GM_5 | 145 | 0.1042 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.08417 | 0.0826 |
| Vorinostat | 180614_BG_03 | 1307 | 0.0710 | 60 | 37 | 13 | 13 | Vorinostat | 9.98 | treatment | 72 | 1 | MCF10A-GM_6 | 97 | 0.0691 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.04909 | 0.0947 |
| Vorinostat | 180614_BG_04 | 1287 | 0.0887 | 88 | 34 | 10 | 4 | Vorinostat | 9.98 | treatment | 72 | 1 | MCF10A-GM_7 | 122 | 0.0866 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.06659 | 0.0907 |
| Vorinostat | 180614_BG_04 | 1317 | 0.1244 | 146 | 36 | 11 | 14 | Vorinostat | 9.98 | treatment | 72 | 1 | MCF10A-GM_8 | 182 | 0.1214 | 889.0 | 105.5 | 17054 | 348.0 | 0.0200 | 0.10142 | 0.0966 |